| Literature DB >> 29104964 |
Erin Gustafson1, Jennifer Pacheco1, Firas Wehbe1, Jonathan Silverberg1, William Thompson1.
Abstract
The current work aims to identify patients with atopic dermatitis for inclusion in genome-wide association studies (GWAS). Here we describe a machine learning-based phenotype algorithm. Using the electronic health record (EHR), we combined coded information with information extracted from encounter notes as features in a lasso logistic regression. Our algorithm achieves high positive predictive value (PPV) and sensitivity, improving on previous algorithms with low sensitivity. These results demonstrate the utility of natural language processing (NLP) and machine learning for EHR-based phenotyping.Entities:
Year: 2017 PMID: 29104964 PMCID: PMC5664951 DOI: 10.1109/ICHI.2017.31
Source DB: PubMed Journal: IEEE Int Conf Healthc Inform