Literature DB >> 24813298

Guidelines of care for the management of atopic dermatitis: section 3. Management and treatment with phototherapy and systemic agents.

Robert Sidbury1, Dawn M Davis2, David E Cohen3, Kelly M Cordoro4, Timothy G Berger4, James N Bergman5, Sarah L Chamlin6, Kevin D Cooper7, Steven R Feldman8, Jon M Hanifin9, Alfons Krol9, David J Margolis10, Amy S Paller6, Kathryn Schwarzenberger11, Robert A Silverman12, Eric L Simpson9, Wynnis L Tom13, Hywel C Williams14, Craig A Elmets15, Julie Block16, Christopher G Harrod17, Wendy Smith Begolka18, Lawrence F Eichenfield13.   

Abstract

Atopic dermatitis is a chronic, pruritic inflammatory dermatosis that affects up to 25% of children and 2% to 3% of adults. This guideline addresses important clinical questions that arise in atopic dermatitis management and care, providing recommendations based on the available evidence. In this third of 4 sections, treatment of atopic dermatitis with phototherapy and systemic immunomodulators, antimicrobials, and antihistamines is reviewed, including indications for use and the risk-benefit profile of each treatment option.
Copyright © 2014 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

Entities:  

Keywords:  atopic dermatitis; azathioprine; cyclosporin A; interferon gamma; methotrexate; mycophenolate mofetil; oral antihistamines; oral antimicrobials; oral steroids; photochemotherapy; phototherapy; systemic therapy

Mesh:

Substances:

Year:  2014        PMID: 24813298      PMCID: PMC4410179          DOI: 10.1016/j.jaad.2014.03.030

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  67 in total

Review 1.  Relieving the pruritus of atopic dermatitis: a meta-analysis.

Authors:  Lindsay G Sher; Jongwha Chang; Isha B Patel; Rajesh Balkrishnan; Alan B Fleischer
Journal:  Acta Derm Venereol       Date:  2012-09       Impact factor: 4.437

2.  An open-label, dose-ranging study of methotrexate for moderate-to-severe adult atopic eczema.

Authors:  S C Weatherhead; S Wahie; N J Reynolds; S J Meggitt
Journal:  Br J Dermatol       Date:  2007-02       Impact factor: 9.302

3.  Oral azathioprine for recalcitrant pediatric atopic dermatitis: clinical response and thiopurine monitoring.

Authors:  Maura Caufield; Wynnis L Tom
Journal:  J Am Acad Dermatol       Date:  2012-08-11       Impact factor: 11.527

4.  Azathioprine in severe adult atopic dermatitis: a double-blind, placebo-controlled, crossover trial.

Authors:  J Berth-Jones; A Takwale; E Tan; G Barclay; S Agarwal; I Ahmed; K Hotchkiss; R A C Graham-Brown
Journal:  Br J Dermatol       Date:  2002-08       Impact factor: 9.302

5.  Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial.

Authors:  Simon J Meggitt; Janine C Gray; Nick J Reynolds
Journal:  Lancet       Date:  2006-03-11       Impact factor: 79.321

6.  Methotrexate and psoriasis: 2009 National Psoriasis Foundation Consensus Conference.

Authors:  Robert E Kalb; Bruce Strober; Gerald Weinstein; Mark Lebwohl
Journal:  J Am Acad Dermatol       Date:  2009-05       Impact factor: 11.527

Review 7.  Atopic dermatitis: a practice parameter update 2012.

Authors:  Lynda Schneider; Stephen Tilles; Peter Lio; Mark Boguniewicz; Lisa Beck; Jennifer LeBovidge; Natalija Novak; David Bernstein; Joann Blessing-Moore; David Khan; David Lang; Richard Nicklas; John Oppenheimer; Jay Portnoy; Christopher Randolph; Diane Schuller; Sheldon Spector; Stephen Tilles; Dana Wallace
Journal:  J Allergy Clin Immunol       Date:  2013-02       Impact factor: 10.793

8.  Azathioprine treatment photosensitizes human skin to ultraviolet A radiation.

Authors:  C M Perrett; S L Walker; P O'Donovan; J Warwick; C A Harwood; P Karran; J M McGregor
Journal:  Br J Dermatol       Date:  2008-05-16       Impact factor: 9.302

9.  The role of psoralen photochemotherapy (PUVA) in the treatment of severe atopic eczema in adolescents.

Authors:  D J Atherton; F Carabott; M T Glover; J L Hawk
Journal:  Br J Dermatol       Date:  1988-06       Impact factor: 9.302

Review 10.  Antihistamines in the pediatric population: achieving optimal outcomes when treating seasonal allergic rhinitis and chronic urticaria.

Authors:  Christine A Schad; David P Skoner
Journal:  Allergy Asthma Proc       Date:  2008 Jan-Feb       Impact factor: 2.587

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  144 in total

1.  A novel oxidative stress marker of atopic dermatitis in infants: thiol-disulfide balance.

Authors:  Gulin Karacan; Nazli Ercan; Ilknur Bostanci; Murat Alisik; Ozcan Erel
Journal:  Arch Dermatol Res       Date:  2020-03-11       Impact factor: 3.017

Review 2.  Treatment of Eczema: Corticosteroids and Beyond.

Authors:  Melanie Chong; Luz Fonacier
Journal:  Clin Rev Allergy Immunol       Date:  2016-12       Impact factor: 8.667

3.  American academy of dermatology.

Authors:  Peter Sonnenreich
Journal:  P T       Date:  2015-06

Review 4.  Placebo effects on itch: a meta-analysis of clinical trials of patients with dermatological conditions.

Authors:  Antoinette I M van Laarhoven; Ineke M van der Sman-Mauriks; A Rogier T Donders; Mathilde C Pronk; Peter C M van de Kerkhof; Andrea W M Evers
Journal:  J Invest Dermatol       Date:  2014-12-01       Impact factor: 8.551

5.  Association between atopic dermatitis and serious cutaneous, multiorgan and systemic infections in US adults.

Authors:  Shanthi Narla; Jonathan I Silverberg
Journal:  Ann Allergy Asthma Immunol       Date:  2018-01       Impact factor: 6.347

6.  Guidelines for the management of atopic dermatitis (eczema) for pharmacists.

Authors:  Ian T Y Wong; Ross T Tsuyuki; Amanda Cresswell-Melville; Philip Doiron; Aaron M Drucker
Journal:  Can Pharm J (Ott)       Date:  2017-05-30

7.  Is new better than tried and tested? Topical atopic dermatitis treatment in context.

Authors:  K Abuabara; C Flohr
Journal:  Br J Dermatol       Date:  2018-03       Impact factor: 9.302

8.  Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch.

Authors:  Joshua J Emrick; Anubhav Mathur; Jessica Wei; Elena O Gracheva; Karsten Gronert; Michael D Rosenblum; David Julius
Journal:  Proc Natl Acad Sci U S A       Date:  2018-11-21       Impact factor: 11.205

9.  A retrospective review of phototherapy in children, at a tertiary paediatric dermatology unit.

Authors:  Ella Seccombe; Matthew David Wynne; Cornelius Clancy; Keith M Godfrey; Adam Fityan
Journal:  Photodermatol Photoimmunol Photomed       Date:  2020-10-04       Impact factor: 3.135

10.  A 12-year-old girl with eczema not responding to treatment.

Authors:  Alexandra Pennal; Elena Pope
Journal:  CMAJ       Date:  2016-08-08       Impact factor: 8.262

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