Literature DB >> 29077947

Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.

Sreenivasa C Ramaiahgari, Suramya Waidyanatha, Darlene Dixon, Michael J DeVito, Richard S Paules, Stephen S Ferguson.   

Abstract

Entities:  

Year:  2017        PMID： 29077947      PMCID： PMC6790530          DOI： 10.1093/toxsci/kfx194

Source DB:  PubMed          Journal:  Toxicol Sci        ISSN： 1096-0929            Impact factor:   4.849


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  12 in total

1.  Clinostat 3D Cell Culture: Protocols for the Preparation and Functional Analysis of Highly Reproducible, Large, Uniform Spheroids and Organoids.

Authors:  Krzysztof Wrzesinski; Helle Sedighi Frandsen; Carlemi Calitz; Chrisna Gouws; Barbara Korzeniowska; Stephen J Fey
Journal:  Methods Mol Biol       Date:  2021

2.  In silico approaches in organ toxicity hazard assessment: current status and future needs in predicting liver toxicity.

Authors:  Arianna Bassan; Vinicius M Alves; Alexander Amberg; Lennart T Anger; Scott Auerbach; Lisa Beilke; Andreas Bender; Mark T D Cronin; Kevin P Cross; Jui-Hua Hsieh; Nigel Greene; Raymond Kemper; Marlene T Kim; Moiz Mumtaz; Tobias Noeske; Manuela Pavan; Julia Pletz; Daniel P Russo; Yogesh Sabnis; Markus Schaefer; David T Szabo; Jean-Pierre Valentin; Joerg Wichard; Dominic Williams; David Woolley; Craig Zwickl; Glenn J Myatt
Journal:  Comput Toxicol       Date:  2021-09-09

Review 3.  Obesity III: Obesogen assays: Limitations, strengths, and new directions.

Authors:  Christopher D Kassotis; Frederick S Vom Saal; Patrick J Babin; Dominique Lagadic-Gossmann; Helene Le Mentec; Bruce Blumberg; Nicole Mohajer; Antoine Legrand; Vesna Munic Kos; Corinne Martin-Chouly; Normand Podechard; Sophie Langouët; Charbel Touma; Robert Barouki; Min Ji Kim; Karine Audouze; Mahua Choudhury; Nitya Shree; Amita Bansal; Sarah Howard; Jerrold J Heindel
Journal:  Biochem Pharmacol       Date:  2022-04-05       Impact factor: 6.100

4.  Next generation sequencing data for use in risk assessment.

Authors:  B Alex Merrick
Journal:  Curr Opin Toxicol       Date:  2019-03-08

5.  Preparation of Three-dimensional (3-D) Human Liver (HepaRG) Cultures for Histochemical and Immunohistochemical Staining and Light Microscopic Evaluation.

Authors:  Natasha P Clayton; Alanna Burwell; Heather Jensen; Barbara F Williams; Quashana D Brown; Pamela Ovwigho; Sreenivasa Ramaiahgari; Tonia Hermon; Darlene Dixon
Journal:  Toxicol Pathol       Date:  2018-08-08       Impact factor: 1.902

6.  Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization.

Authors:  Katie Paul Friedman; Matthew Gagne; Lit-Hsin Loo; Panagiotis Karamertzanis; Tatiana Netzeva; Tomasz Sobanski; Jill A Franzosa; Ann M Richard; Ryan R Lougee; Andrea Gissi; Jia-Ying Joey Lee; Michelle Angrish; Jean Lou Dorne; Stiven Foster; Kathleen Raffaele; Tina Bahadori; Maureen R Gwinn; Jason Lambert; Maurice Whelan; Mike Rasenberg; Tara Barton-Maclaren; Russell S Thomas
Journal:  Toxicol Sci       Date:  2020-01-01       Impact factor: 4.849

7.  Improving natural product research translation: From source to clinical trial.

Authors:  Barbara C Sorkin; Adam J Kuszak; Gregory Bloss; Naomi K Fukagawa; Freddie Ann Hoffman; Mahtab Jafari; Bruce Barrett; Paula N Brown; Frederic D Bushman; Steven J Casper; Floyd H Chilton; Christopher S Coffey; Mario G Ferruzzi; D Craig Hopp; Mairead Kiely; Daniel Lakens; John B MacMillan; David O Meltzer; Marco Pahor; Jeffrey Paul; Kathleen Pritchett-Corning; Sara K Quinney; Barbara Rehermann; Kenneth D R Setchell; Nisha S Sipes; Jacqueline M Stephens; D Lansing Taylor; Hervé Tiriac; Michael A Walters; Dan Xi; Giovanna Zappalá; Guido F Pauli
Journal:  FASEB J       Date:  2019-12-10       Impact factor: 5.834

8.  Targeting CYP4A attenuates hepatic steatosis in a novel multicellular organotypic liver model.

Authors:  Minji Lee; Seon Ju Mun; Jae-Sung Ryu; Sin-Hyoung Hong; Ho-Joon Lee; Hyo-Suk Ahn; Kyung-Sook Chung; Gun-Hwa Kim; Myung Jin Son
Journal:  J Biol Eng       Date:  2019-08-08       Impact factor: 4.355

Review 9.  The evolution of strategies to minimise the risk of human drug-induced liver injury (DILI) in drug discovery and development.

Authors:  Paul A Walker; Stephanie Ryder; Andrea Lavado; Clive Dilworth; Robert J Riley
Journal:  Arch Toxicol       Date:  2020-05-06       Impact factor: 5.153

10.  Characterization of primary mouse hepatocyte spheroids as a model system to support investigations of drug-induced liver injury.

Authors:  Manisha Nautiyal; Rani J Qasem; John K Fallon; Kristina K Wolf; Jingli Liu; Darlene Dixon; Philip C Smith; Merrie Mosedale
Journal:  Toxicol In Vitro       Date:  2020-10-03       Impact factor: 3.500
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