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Literature DB >> 29063959

Update on investigations pertaining to the pathogenesis of biliary atresia.

Abstract

Biliary atresia is a devastating biliary disease of neonates that results in liver transplantation for the vast majority. The etiology of biliary atresia is unknown and is likely multifactorial, with components of genetic predisposition, environmental trigger and autoimmunity contributing to disease pathogenesis. This review highlights recent work related to investigations of disease pathogenesis in biliary atresia.

Entities: Chemical Disease Gene Mutation Species

Keywords: Autoimmunity; Genetic predisposition; Neonatal cholestasis

Mesh：

Year: 2017 PMID： 29063959 PMCID： PMC5894874 DOI： 10.1007/s00383-017-4172-6

Source DB: PubMed Journal: Pediatr Surg Int ISSN： 0179-0358 Impact factor: 1.827

98 in total

1. Toll-like receptor mRNA expression in liver tissue from patients with biliary atresia.

Authors: Takeshi Saito; Tomoro Hishiki; Keita Terui; Tetsuya Mitsunaga; Elena Terui; Mitsuyuki Nakata; Hideo Yoshida
Journal: J Pediatr Gastroenterol Nutr Date: 2011-12 Impact factor: 2.839

2. Cytomegalovirus infection is associated with increased inflammation and severe bile duct damage in rat liver allografts.

Authors: T Martelius; L Krogerus; K Höckerstedt; C Bruggeman; I Lautenschlager
Journal: Hepatology Date: 1998-04 Impact factor: 17.425

3. Regulatory T cells inhibit Th1 cell-mediated bile duct injury in murine biliary atresia.

Authors: Rebecca M Tucker; Amy G Feldman; Erika K Fenner; Cara L Mack
Journal: J Hepatol Date: 2013-05-14 Impact factor: 25.083

4. Impact of age at Kasai operation on its results in late childhood and adolescence: a rational basis for biliary atresia screening.

Authors: Marie-Odile Serinet; Barbara E Wildhaber; Pierre Broué; Alain Lachaux; Jacques Sarles; Emmanuel Jacquemin; Frédéric Gauthier; Christophe Chardot
Journal: Pediatrics Date: 2009-05 Impact factor: 7.124

5. Risk factors for isolated biliary atresia, National Birth Defects Prevention Study, 1997-2002.

Authors: Natalie S The; Margaret A Honein; Alissa R Caton; Cynthia A Moore; Anna Maria Siega-Riz; Charlotte M Druschel
Journal: Am J Med Genet A Date: 2007-10-01 Impact factor: 2.802

6. Innate immune response to double-stranded RNA in biliary epithelial cells is associated with the pathogenesis of biliary atresia.

Authors: Kenichi Harada; Yasunori Sato; Keita Itatsu; Kumiko Isse; Hiroko Ikeda; Mitsue Yasoshima; Yoh Zen; Akira Matsui; Yasuni Nakanuma
Journal: Hepatology Date: 2007-10 Impact factor: 17.425

7. Comparative studies of biliary atresia in the human newborn and reovirus-induced cholangitis in weanling mice.

Authors: B Bangaru; R Morecki; J H Glaser; L M Gartner; M S Horwitz
Journal: Lab Invest Date: 1980-11 Impact factor: 5.662

8. Incidence of biliary atresia associated congenital malformations: A retrospective multicenter study in China.

Authors: Jianghua Zhan; Jiexiong Feng; Yajun Chen; Juncheng Liu; Bin Wang
Journal: Asian J Surg Date: 2016-07-07 Impact factor: 2.767

9. Congenital cytomegalovirus infection: three autopsy case reports.

Authors: H M Ko; K S Kim; J W Park; Y J Lee; M Y Lee; M C Lee; C S Park; S W Juhng; C Choi
Journal: J Korean Med Sci Date: 2000-06 Impact factor: 2.153

10. Cholangiopathy with respect to biliary innate immunity.

Authors: Kenichi Harada; Yasuni Nakanuma
Journal: Int J Hepatol Date: 2011-08-11

17 in total

1. Impaired Redox and Protein Homeostasis as Risk Factors and Therapeutic Targets in Toxin-Induced Biliary Atresia.

Authors: Xiao Zhao; Kristin Lorent; Diana Escobar-Zarate; Ramakrishnan Rajagopalan; Kathleen M Loomes; Kevin Gillespie; Clementina Mesaros; Michelle A Estrada; Ian A Blair; Jeffrey D Winkler; Nancy B Spinner; Marcella Devoto; Michael Pack
Journal: Gastroenterology Date: 2020-06-04 Impact factor: 22.682

Review 2. Biliary Atresia in Children: Update on Disease Mechanism, Therapies, and Patient Outcomes.

Authors: Swati Antala; Sarah A Taylor
Journal: Clin Liver Dis Date: 2022-06-25 Impact factor: 6.265

3. MicroRNA-499 rs3746444 polymorphism in Egyptian children with biliary atresia.

Authors: Eman Gawish; Elhamy Abd El-Monem; Mona El-Abd; Gihan Ahmed Sobhy; Heba Ghanem
Journal: Clin Exp Hepatol Date: 2020-09-30

4. Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation Syndrome.

Authors: John-Paul Berauer; Anya I Mezina; David T Okou; Aniko Sabo; Donna M Muzny; Richard A Gibbs; Madhuri R Hegde; Pankaj Chopra; David J Cutler; David H Perlmutter; Laura N Bull; Richard J Thompson; Kathleen M Loomes; Nancy B Spinner; Ramakrishnan Rajagopalan; Stephen L Guthery; Barry Moore; Mark Yandell; Sanjiv Harpavat; John C Magee; Binita M Kamath; Jean P Molleston; Jorge A Bezerra; Karen F Murray; Estella M Alonso; Philip Rosenthal; Robert H Squires; Kasper S Wang; Milton J Finegold; Pierre Russo; Averell H Sherker; Ronald J Sokol; Saul J Karpen
Journal: Hepatology Date: 2019-03-21 Impact factor: 17.425

5. Gene Expression Signatures Associated With Survival Times of Pediatric Patients With Biliary Atresia Identify Potential Therapeutic Agents.

Authors: Zhenhua Luo; Pranavkumar Shivakumar; Reena Mourya; Sridevi Gutta; Jorge A Bezerra
Journal: Gastroenterology Date: 2019-06-19 Impact factor: 33.883

Review 6. Recent advances in understanding biliary atresia.

Authors: Andrew Wehrman; Orith Waisbourd-Zinman; Rebecca G Wells
Journal: F1000Res Date: 2019-02-25

7. Transcriptional profiling of pediatric cholestatic livers identifies three distinct macrophage populations.

Authors: Sarah A Taylor; Shang-Yang Chen; Gaurav Gadhvi; Liang Feng; Kyle D Gromer; Hiam Abdala-Valencia; Kiwon Nam; Salina T Dominguez; Anna B Montgomery; Paul A Reyfman; Lorena Ostilla; Joshua B Wechsler; Carla M Cuda; Richard M Green; Harris Perlman; Deborah R Winter
Journal: PLoS One Date: 2021-01-07 Impact factor: 3.240