Literature DB >> 2906044

A primary map of ten DNA markers and two serological markers for human chromosome 19.

Y Nakamura1, M Lathrop, P O'Connell, M Leppert, J M Lalouel, R White.   

Abstract

We have constructed a primary map of 10 DNA and 2 protein markers for chromosome 19. Three of the markers define loci with a variable number of tandem repeats (VNTRs); 3 define genes--insulin receptor, low-density lipoprotein (LDL) receptor, and apolipoprotein CII; and 2 are classical markers for blood group antigens (Lewis and Secretor). The estimated genetic distance covered by the map is 137 cM in males and 189 cM in females. In some regions of the chromosome we found significant differences in recombination frequencies according to sex. This set of markers will be efficient for linkage studies in families segregating genetic defects and will provide anchor points for a high-resolution map of chromosome 19.

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Year:  1988        PMID： 2906044     DOI： 10.1016/0888-7543(88)90161-9

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  17 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Assignment of the gene for central core disease to chromosome 19.

Authors:  E A Haan; C J Freemantle; J A McCure; K L Friend; J C Mulley
Journal:  Hum Genet       Date:  1990-12       Impact factor: 4.132

3.  The physical map of chromosome arm 19q: some new assignments, confirmations and re-assessments.

Authors:  J D Brook; S J Knight; S H Roberts; H G Harley; K V Walsh; S A Rundle; K Freyne; M C Koch; N D Epstein; B Wieringa
Journal:  Hum Genet       Date:  1991-05       Impact factor: 4.132

Review 4.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 5.  Mouse chromosome 8.

Authors:  J D Ceci
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

6.  Genetic linkage map of 46 DNA markers on human chromosome 16.

Authors:  T P Keith; P Green; S T Reeders; V A Brown; P Phipps; A Bricker; K Falls; K S Rediker; J A Powers; C Hogan
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

7.  Use of variable simple sequence motifs as genetic markers: application to study of myotonic dystrophy.

Authors:  H J Smeets; H G Brunner; H H Ropers; B Wieringa
Journal:  Hum Genet       Date:  1989-10       Impact factor: 4.132

8.  Long-range restriction map of a region of human chromosome 19 containing the apolipoprotein genes, a CLL-associated translocation breakpoint, and two polymorphic MluI sites.

Authors:  D J Shaw; H G Harley; J D Brook; T W McKeithan
Journal:  Hum Genet       Date:  1989-08       Impact factor: 4.132

9.  Sequences flanking the repeat arrays of human minisatellites: association with tandem and dispersed repeat elements.

Authors:  J A Armour; Z Wong; V Wilson; N J Royle; A J Jeffreys
Journal:  Nucleic Acids Res       Date:  1989-07-11       Impact factor: 16.971

10.  The 1.5-Mb region spanning the myotonic dystrophy locus shows uniform recombination frequency.

Authors:  G G Shutler; A E MacKenzie; R G Korneluk
Journal:  Am J Hum Genet       Date:  1994-01       Impact factor: 11.025
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