Literature DB >> 29055782

Interest in multipurpose prevention technologies to prevent HIV/STIs and unintended pregnancy among young women in the United States.

Jenna S Hynes1, Jessica M Sales2, Anandi N Sheth3, Eva Lathrop4, Lisa B Haddad5.   

Abstract

OBJECTIVE: High rates of sexually transmitted infections (STIs) and unintended pregnancy suggest a role for multipurpose prevention technologies (MPTs) designed to combine contraception and infection prophylaxis into one unified method. This study aims to determine factors associated with interest in MPTs among US women. STUDY
DESIGN: We administered a national cross-sectional survey via MTurk. Eligibility criteria included female gender, age 18-29 years, residence in the USA, and sexual activity with a male partner in the past three months. In total, 835 surveys were suitable for analysis. Bivariable and multivariable logistic regressions were performed to determine factors associated with interest in MPTs.
RESULTS: Eighty-three percent of women were interested in MPTs. Factors associated with interest included oral sex in the past three months (aOR 1.87, 95% CI 1.07, 3.53), recent use of oral contraceptive pills (OCPs; aOR 1.78, 95% CI 1.08, 2.93), HIV test within one year (aOR 2.10, 95% CI 1.29, 3.40), and increased STI worry score (aOR 1.98, 95% CI 1.36, 2.86). No use of contraception in the past three months was associated with decreased interest in MPTs (aOR 0.31, 95% CI 0.17, 0.58). HIV risk factors including race were not associated with MPT interest.
CONCLUSION: Our data show that young, sexually active, US women are interested in MPTs. Women who used contraception, specifically OCPs, or evidenced concern for infection were most likely to be interested in such a product. Women reporting unsafe sexual habits were less likely to be interested, highlighting the importance of HIV/STI prevention education. IMPLICATIONS: Women in the USA are interested in multipurpose prevention technologies, particularly those women who currently use contraception or are concerned about their risk of infection. Our results emphasize the importance of moving forward with MPT development as well as continued HIV/STI prevention education.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Contraception; HIV prophylaxis; Multipurpose prevention technologies; STIs

Mesh:

Year:  2017        PMID: 29055782      PMCID: PMC5828781          DOI: 10.1016/j.contraception.2017.10.006

Source DB:  PubMed          Journal:  Contraception        ISSN: 0010-7824            Impact factor:   3.375


  18 in total

Review 1.  An update on multipurpose prevention technologies for the prevention of HIV transmission and pregnancy.

Authors:  David R Friend
Journal:  Expert Opin Drug Deliv       Date:  2016-01-22       Impact factor: 6.648

2.  Validation of the worry about sexual outcomes scale for use in STI/HIV prevention interventions for adolescent females.

Authors:  Jessica M Sales; Josh Spitalnick; Robin R Milhausen; Gina M Wingood; Ralph J DiClemente; Laura F Salazar; Richard A Crosby
Journal:  Health Educ Res       Date:  2008-03-18

3.  Use of Dual Methods for Protection from Unintended Pregnancy and Sexually Transmitted Diseases in Adolescent African American Women.

Authors:  Melissa Kottke; Maura K Whiteman; Joan Marie Kraft; Peggy Goedken; Jeffrey Wiener; Athena P Kourtis; Ralph DiClemente
Journal:  J Pediatr Adolesc Gynecol       Date:  2015-04-21       Impact factor: 1.814

4.  Beyond HIV microbicides: multipurpose prevention technology products.

Authors:  R K Malcolm; P Boyd; C F McCoy; D J Murphy
Journal:  BJOG       Date:  2014-10       Impact factor: 6.531

5.  Aligning product development and user perspectives: social-behavioural dimensions of multipurpose prevention technologies.

Authors:  M Brady; E Tolley
Journal:  BJOG       Date:  2014-10       Impact factor: 6.531

Review 6.  Progress and challenges to male and female condom use in South Africa.

Authors:  Mags E Beksinska; Jennifer A Smit; Joanne E Mantell
Journal:  Sex Health       Date:  2012-03       Impact factor: 2.706

7.  Interest in multipurpose prevention of HIV and pregnancy: perspectives of women, men, health professionals and community stakeholders in two vaginal gel studies in southern Africa.

Authors:  C Woodsong; P Musara; A Chandipwisa; E Montgomery; P Alleman; M Chirenje; T Chipato; F Martinson; I Hoffman
Journal:  BJOG       Date:  2014-10       Impact factor: 6.531

8.  Amazon's Mechanical Turk: A New Source of Inexpensive, Yet High-Quality, Data?

Authors:  Michael Buhrmester; Tracy Kwang; Samuel D Gosling
Journal:  Perspect Psychol Sci       Date:  2011-02-03

9.  Young adult women and correlates of potential adoption of pre-exposure prophylaxis (PrEP): results of a national survey.

Authors:  Anna Rubtsova; Gina M Wingood; Kristin Dunkle; Christina Camp; Ralph J DiClemente
Journal:  Curr HIV Res       Date:  2013-10       Impact factor: 1.581

10.  HIV pre-exposure prophylaxis for women.

Authors:  Anandi N Sheth; Charlotte P Rolle; Monica Gandhi
Journal:  J Virus Erad       Date:  2016-07-01
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  12 in total

1.  Preferred Product Attributes of Potential Multipurpose Prevention Technologies for Unintended Pregnancy and Sexually Transmitted Infections or HIV Among U.S. Women.

Authors:  Jenna S Hynes; Anandi N Sheth; Eva Lathrop; Jessica M Sales; Lisa B Haddad
Journal:  J Womens Health (Larchmt)       Date:  2019-01-04       Impact factor: 2.681

2.  Mapping Interests in Event-Driven and Long-Acting Pre-exposure Prophylaxis Formulations onto the HIV Risk Environment of Street-Based Female Sex Workers: A Latent Class Analysis.

Authors:  Joseph G Rosen; Ju Nyeong Park; Kristin E Schneider; Rebecca Hamilton White; S Wilson Beckham; Jennifer L Glick; Katherine H A Footer; Susan G Sherman
Journal:  AIDS Behav       Date:  2022-04-01

3.  Making the Case for Joint Decision-Making in Future Multipurpose Prevention Technology (MPT) Choice: Qualitative Findings on MPT Attribute Preferences from the CUPID Study (MTN-045).

Authors:  Nivedita L Bhushan; Petina Musara; Miriam Hartmann; Marie C D Stoner; Shweta R Shah; Josephine Nabukeera; Ivan Rukundo; Prisca Mutero; Megan A Lewis; Jeanna Piper; Mary Kate Shapley-Quinn; Juliane Etima; Alexandra M Minnis
Journal:  J Int AIDS Soc       Date:  2022-10       Impact factor: 6.707

4.  Reproductive Life Goals: A Systematic Review of Pregnancy Planning Intentions, Needs, and Interventions Among Women Involved in U.S. Criminal Justice Systems.

Authors:  Emily Hoff; Zoe M Adams; Alyssa Grimshaw; Dawn A Goddard-Eckrich; Anindita Dasgupta; Sangini S Sheth; Jaimie P Meyer
Journal:  J Womens Health (Larchmt)       Date:  2020-06-23       Impact factor: 2.681

5.  Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides.

Authors:  Cristina Tintori; Giulia Iovenitti; Elisa Rita Ceresola; Roberto Ferrarese; Claudio Zamperini; Annalaura Brai; Giulio Poli; Elena Dreassi; Valeria Cagno; David Lembo; Filippo Canducci; Maurizio Botta
Journal:  PLoS One       Date:  2018-06-05       Impact factor: 3.240

Review 6.  Recent Advances in Polymer-Based Vaginal Drug Delivery Systems.

Authors:  Tomasz Osmałek; Anna Froelich; Barbara Jadach; Adam Tatarek; Piotr Gadziński; Aleksandra Falana; Kinga Gralińska; Michał Ekert; Vinam Puri; Joanna Wrotyńska-Barczyńska; Bozena Michniak-Kohn
Journal:  Pharmaceutics       Date:  2021-06-15       Impact factor: 6.321

7.  Estimating the market size for a dual prevention pill: adding contraception to pre-exposure prophylaxis (PrEP) to increase uptake.

Authors:  Lorna Begg; Rebecca Brodsky; Barbara Friedland; Sanyukta Mathur; Jim Sailer; George Creasy
Journal:  BMJ Sex Reprod Health       Date:  2020-07-31

8.  Giving voice to the end-user: input on multipurpose prevention technologies from the perspectives of young women in Kenya and South Africa.

Authors:  Alexandra M Minnis; Emily Krogstad; Mary Kate Shapley-Quinn; Kawango Agot; Khatija Ahmed; L Danielle Wagner; Ariane van der Straten
Journal:  Sex Reprod Health Matters       Date:  2021-12

9.  Contraceptive Technologies: Looking Ahead to New Approaches to Increase Options for Family Planning.

Authors:  Lisa B Haddad; John W Townsend; Regine Sitruk-Ware
Journal:  Clin Obstet Gynecol       Date:  2021-09-01       Impact factor: 1.966

Review 10.  Engineering monoclonal antibody-based contraception and multipurpose prevention technologies†.

Authors:  Deborah J Anderson; Joseph A Politch; Richard A Cone; Larry Zeitlin; Samuel K Lai; Philip J Santangelo; Thomas R Moench; Kevin J Whaley
Journal:  Biol Reprod       Date:  2020-08-04       Impact factor: 4.161

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