Literature DB >> 30615569

Preferred Product Attributes of Potential Multipurpose Prevention Technologies for Unintended Pregnancy and Sexually Transmitted Infections or HIV Among U.S. Women.

Jenna S Hynes1, Anandi N Sheth2, Eva Lathrop3, Jessica M Sales4, Lisa B Haddad3.   

Abstract

Background: Multipurpose prevention technologies (MPTs) are being developed to simultaneously protect women from unintended pregnancy and sexually transmitted infections (STIs) or human immunodeficiency virus. This study aims to determine MPT characteristics desired by young women in the United States (U.S.). Materials and
Methods: This is a cross-sectional national survey administered online by MTurk. Eligibility criteria included female sex, age 18-29 years, U.S. residence, and sexual activity with a male partner in the past 3 months. MPT characteristics were rated for importance. Odds ratios were generated to explore associations between demographics, sexual behaviors, and prior contraceptive use and likelihood of using various MPT formulations.
Results: Of 835 women, the largest proportion reported being likely to use MPTs in the form of injectables (45.6%), followed by vaginal gels (33.7%), vaginal rings (26.3%) and diaphragms (17.3%). Women with prior experience using a specific method of contraception appeared more likely to try an MPT of the same form. Women concerned about STIs and unwanted pregnancy, or with a history of such undesirable outcomes, expressed higher likelihood of use for a broad range of products. Women indicated that safety and efficacy at preventing pregnancy were the most important product characteristics when choosing an MPT. Conclusions: MPTs in the form of injectables are most highly desired, but many women would use vaginal methods, highlighting the importance of developing different delivery methods. Women desire safety and emphasize contraceptive efficacy over infection prevention. MPT preferences must be considered during product development to promote future acceptance among young women in the U.S.

Entities:  

Keywords:  HIV; STIs; contraception; multipurpose prevention technology; unintended pregnancy

Mesh:

Year:  2019        PMID: 30615569      PMCID: PMC6537110          DOI: 10.1089/jwh.2018.7001

Source DB:  PubMed          Journal:  J Womens Health (Larchmt)        ISSN: 1540-9996            Impact factor:   2.681


  26 in total

Review 1.  An update on multipurpose prevention technologies for the prevention of HIV transmission and pregnancy.

Authors:  David R Friend
Journal:  Expert Opin Drug Deliv       Date:  2016-01-22       Impact factor: 6.648

2.  Aligning product development and user perspectives: social-behavioural dimensions of multipurpose prevention technologies.

Authors:  M Brady; E Tolley
Journal:  BJOG       Date:  2014-10       Impact factor: 6.531

3.  Attitudes and program preferences of African-American urban young adults about pre-exposure prophylaxis (PrEP).

Authors:  Dawn K Smith; Lauren Toledo; Donna Jo Smith; Mary Anne Adams; Richard Rothenberg
Journal:  AIDS Educ Prev       Date:  2012-10

4.  Tenofovir-based preexposure prophylaxis for HIV infection among African women.

Authors:  Jeanne M Marrazzo; Gita Ramjee; Barbra A Richardson; Kailazarid Gomez; Nyaradzo Mgodi; Gonasagrie Nair; Thesla Palanee; Clemensia Nakabiito; Ariane van der Straten; Lisa Noguchi; Craig W Hendrix; James Y Dai; Shayhana Ganesh; Baningi Mkhize; Marthinette Taljaard; Urvi M Parikh; Jeanna Piper; Benoît Mâsse; Cynthia Grossman; James Rooney; Jill L Schwartz; Heather Watts; Mark A Marzinke; Sharon L Hillier; Ian M McGowan; Z Mike Chirenje
Journal:  N Engl J Med       Date:  2015-02-05       Impact factor: 91.245

5.  Racial differences and correlates of potential adoption of preexposure prophylaxis: results of a national survey.

Authors:  Gina M Wingood; Kristin Dunkle; Christina Camp; Shilpa Patel; Julia E Painter; Anna Rubtsova; Ralph J DiClemente
Journal:  J Acquir Immune Defic Syndr       Date:  2013-06-01       Impact factor: 3.731

Review 6.  Multipurpose prevention technologies: products in development.

Authors:  David R Friend; Justin T Clark; Patrick F Kiser; Meredith R Clark
Journal:  Antiviral Res       Date:  2013-11-01       Impact factor: 5.970

7.  Preexposure prophylaxis for HIV infection among African women.

Authors:  Lut Van Damme; Amy Corneli; Khatija Ahmed; Kawango Agot; Johan Lombaard; Saidi Kapiga; Mookho Malahleha; Fredrick Owino; Rachel Manongi; Jacob Onyango; Lucky Temu; Modie Constance Monedi; Paul Mak'Oketch; Mankalimeng Makanda; Ilse Reblin; Shumani Elsie Makatu; Lisa Saylor; Haddie Kiernan; Stella Kirkendale; Christina Wong; Robert Grant; Angela Kashuba; Kavita Nanda; Justin Mandala; Katrien Fransen; Jennifer Deese; Tania Crucitti; Timothy D Mastro; Douglas Taylor
Journal:  N Engl J Med       Date:  2012-07-11       Impact factor: 91.245

8.  Women want Pre-Exposure Prophylaxis but are Advised Against it by Their HIV-positive Counterparts.

Authors:  Lakshmi Goparaju; Laure S Experton; Nathan C Praschan; Lari Warren-Jeanpiere; Mary A Young; Seble Kassaye
Journal:  J AIDS Clin Res       Date:  2015-11

9.  HIV pre-exposure prophylaxis for women.

Authors:  Anandi N Sheth; Charlotte P Rolle; Monica Gandhi
Journal:  J Virus Erad       Date:  2016-07-01

Review 10.  Contraception for the HIV-positive woman: a review of interactions between hormonal contraception and antiretroviral therapy.

Authors:  Jennifer A Robinson; Roxanne Jamshidi; Anne E Burke
Journal:  Infect Dis Obstet Gynecol       Date:  2012-08-14
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  3 in total

1.  The Dose Response: Perceptions of People Living with HIV in the United States on Alternatives to Oral Daily Antiretroviral Therapy.

Authors:  Karine Dubé; Shadi Eskaf; David Evans; John Sauceda; Parya Saberi; Brandon Brown; Dawn Averitt; Krista Martel; Maria Meija; Danielle Campbell; Liz Barr; John Kanazawa; Kelly Perry; Hursch Patel; Stuart Luter; Tonia Poteat; Judith D Auerbach; David A Wohl
Journal:  AIDS Res Hum Retroviruses       Date:  2019-12-04       Impact factor: 2.205

2.  Vaginal ring acceptability: A systematic review and meta-analysis of vaginal ring experiences from around the world.

Authors:  Kathleen Ridgeway; Elizabeth T Montgomery; Kevin Smith; Kristine Torjesen; Ariane van der Straten; Sharon L Achilles; Jennifer B Griffin
Journal:  Contraception       Date:  2021-10-10       Impact factor: 3.051

3.  Contraception as a Potential Gateway to Pre-Exposure Prophylaxis: US Women's Pre-Exposure Prophylaxis Modality Preferences Align with Their Birth Control Practices.

Authors:  Sarah K Calabrese; Rachel W Galvao; John F Dovidio; Tiara C Willie; Cara B Safon; Clair Kaplan; Abigail Caldwell; Oni Blackstock; Nicole J Phillips; Trace S Kershaw
Journal:  AIDS Patient Care STDS       Date:  2020-03       Impact factor: 5.078

  3 in total

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