Literature DB >> 25335842

Beyond HIV microbicides: multipurpose prevention technology products.

R K Malcolm1, P Boyd, C F McCoy, D J Murphy.   

Abstract

Multipurpose prevention technologies (MPTs) that aim to simultaneously prevent unintended pregnancy, HIV-1 infection and other sexually transmitted infections are among the most innovative and complex products currently in development within women's sexual and reproductive health care. In this review article, MPTs are placed within the wider context of combination products, combination drug products and multi-indication products. The current MPT product landscape is mapped and assessed with reference to existing products for the corresponding single indications, before identifying the gaps in the current MPT product pipeline and highlighting priority products and challenges moving forward.
© 2014 Royal College of Obstetricians and Gynaecologists.

Entities:  

Keywords:  MPTs; combination products; contraception; microbicide

Mesh：

Substances：

Year:  2014        PMID： 25335842     DOI： 10.1111/1471-0528.12852

Source DB:  PubMed          Journal:  BJOG        ISSN： 1470-0328            Impact factor:   6.531


  8 in total

1.  Preferred Product Attributes of Potential Multipurpose Prevention Technologies for Unintended Pregnancy and Sexually Transmitted Infections or HIV Among U.S. Women.

Authors:  Jenna S Hynes; Anandi N Sheth; Eva Lathrop; Jessica M Sales; Lisa B Haddad
Journal:  J Womens Health (Larchmt)       Date:  2019-01-04       Impact factor: 2.681

2.  MZC Gel Inhibits SHIV-RT and HSV-2 in Macaque Vaginal Mucosa and SHIV-RT in Rectal Mucosa.

Authors:  Giulia Calenda; Guillermo Villegas; Patrick Barnable; Claudia Litterst; Keith Levendosky; Agegnehu Gettie; Michael L Cooney; James Blanchard; José A Fernández-Romero; Thomas M Zydowsky; Natalia Teleshova
Journal:  J Acquir Immune Defic Syndr       Date:  2017-03-01       Impact factor: 3.731

3.  Interest in multipurpose prevention technologies to prevent HIV/STIs and unintended pregnancy among young women in the United States.

Authors:  Jenna S Hynes; Jessica M Sales; Anandi N Sheth; Eva Lathrop; Lisa B Haddad
Journal:  Contraception       Date:  2017-10-18       Impact factor: 3.375

4.  Moving the Message Beyond the Methods: Toward Integration of Unintended Pregnancy and Sexually Transmitted Infection/HIV Prevention.

Authors:  Riley J Steiner; Nicole Liddon; Andrea L Swartzendruber; Karen Pazol; Jessica M Sales
Journal:  Am J Prev Med       Date:  2017-12-26       Impact factor: 6.604

5.  Triple combination MPT vaginal microbicide using curcumin and efavirenz loaded lactoferrin nanoparticles.

Authors:  Yeruva Samrajya Lakshmi; Prashant Kumar; Golla Kishore; C Bhaskar; Anand K Kondapi
Journal:  Sci Rep       Date:  2016-05-06       Impact factor: 4.379

6.  In vitro drug release, mechanical performance and stability testing of a custom silicone elastomer vaginal ring releasing dapivirine and levonorgestrel.

Authors:  Diarmaid J Murphy; Yahya H Dallal Bashi; Clare F McCoy; Peter Boyd; Leeanne Brown; François Martin; Nicole McMullen; Kyle Kleinbeck; Bindi Dangi; Patrick Spence; Bashir Hansraj; Bríd Devlin; R Karl Malcolm
Journal:  Int J Pharm X       Date:  2022-01-25

7.  Silicone elastomer formulations for improved performance of a multipurpose vaginal ring releasing dapivirine and levonorgestrel.

Authors:  Yahya H Dallal Bashi; Diarmaid J Murphy; Clare F McCoy; Peter Boyd; Leeanne Brown; Matthew Kihara; François Martin; Nicole McMullen; Kyle Kleinbeck; Bindi Dangi; Patrick Spence; Bashir Hansraj; Brid Devlin; R Karl Malcolm
Journal:  Int J Pharm X       Date:  2021-07-14

8.  The Tablets, Ring, Injections as Options (TRIO) study: what young African women chose and used for future HIV and pregnancy prevention.

Authors:  Ariane van der Straten; Kawango Agot; Khatija Ahmed; Rachel Weinrib; Erica N Browne; Kgahlisho Manenzhe; Fredrick Owino; Jill Schwartz; Alexandra Minnis
Journal:  J Int AIDS Soc       Date:  2018-03       Impact factor: 5.396
  8 in total

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