Lei Zhao1,2, Aishi Liu2, Youmin Guo3. 1. Department of Radiology, The First Affiliated Hospital Of Xi'an Jiaotong University, No. 277 Yanta West Street, Xi'an, 710061, Shanxi, China. 2. Department of Radiology, The Affiliated Hospital of Inner Mongolia Medical University, No. 1 Tongdao North Street, Hohhot, 010050, Inner Mongolia, China. 3. Department of Radiology, The First Affiliated Hospital Of Xi'an Jiaotong University, No. 277 Yanta West Street, Xi'an, 710061, Shanxi, China. 281005117@qq.com.
Abstract
PURPOSE: To optimize and evaluate an ultra-low-dose (ULD) technique for CT coronary angiography (CTCA). MATERIALS AND METHODS:Eighty-two patients were randomly divided into two groups. ULD and routine CTCA were performed in groups A and B. Image quality, radiation dose and contrast agent were evaluated. RESULTS: The effective dose (ED) was 0.20 ± 0.01 mSv for the ULD technique, a decrease of 87% (t = - 21.182, P < 0.001) compared with the control group. The total iodine content was 8.10 ± 0 g, a decrease of 62% (t = - 73.458, P < 0.001) compared with 21.10 ± 1.15 g for the control group. The assessment rates for both groups were the same (99.26 vs 99.64%, χ 2 = 0.727, P = 0.394). The contrast-to-noise ratio was 19.31 ± 7.95 for group A and 20.73 ± 5.07 for group B: the difference was not statistically significant (t = - 1.678, P = 0.095). CONCLUSION: Using an ultra-low radiation dose and contrast agent technique, while maintaining an assessable image and improving the safety of the medical examination, was a feasible and reliable method for CTCA.
RCT Entities:
PURPOSE: To optimize and evaluate an ultra-low-dose (ULD) technique for CT coronary angiography (CTCA). MATERIALS AND METHODS: Eighty-two patients were randomly divided into two groups. ULD and routine CTCA were performed in groups A and B. Image quality, radiation dose and contrast agent were evaluated. RESULTS: The effective dose (ED) was 0.20 ± 0.01 mSv for the ULD technique, a decrease of 87% (t = - 21.182, P < 0.001) compared with the control group. The total iodine content was 8.10 ± 0 g, a decrease of 62% (t = - 73.458, P < 0.001) compared with 21.10 ± 1.15 g for the control group. The assessment rates for both groups were the same (99.26 vs 99.64%, χ 2 = 0.727, P = 0.394). The contrast-to-noise ratio was 19.31 ± 7.95 for group A and 20.73 ± 5.07 for group B: the difference was not statistically significant (t = - 1.678, P = 0.095). CONCLUSION: Using an ultra-low radiation dose and contrast agent technique, while maintaining an assessable image and improving the safety of the medical examination, was a feasible and reliable method for CTCA.
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