Miho Watanabe Nemoto1, Yuma Iwai2, Gentaro Togasaki2, Marie Kurokawa2, Rintarou Harada2, Hiroki Kobayashi2, Takashi Uno2. 1. Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan. mwatanabe@hospital.chiba-u.jp. 2. Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.
Abstract
PURPOSE: We propose a method of image-guided brachytherapy (IGBT) that combines MRI-based target volume delineation for the first fraction with CT datasets of subsequent fractions, using an automatic, applicator-based co-registration, and report our preliminary experience. MATERIALS AND METHODS: The MRI of the first fraction was used for the first brachytherapy planning. For each subsequent brachytherapy fraction, after the same applicator insertion, a new CT scan with the applicator in place was obtained. The MR image set was registered to the subsequent brachytherapy treatment planning CT using the applicator for rigid body registration. To demonstrate the registration quality, we used here the Dice index as a measurement of tandem delineation overlap between CT and MRI. RESULTS: The median Dice index was 0.879 (range 0.610-0.932), which indicated that the contours on CT and MRI fitted well. With this combination method, the median D90 of HR CTV and the calculated D2 cm3 of the bladder, rectum, and sigmoid in each fraction were 7.2 (4.0-10.4), 5.9 (2.3-7.7), 4.0 (1.9-6.7), and 3.8 (0.6-7.2) Gy, respectively. CONCLUSION: Our described method of MRI-guided IGBT offers a practical option for the benefits of target delineation.
PURPOSE: We propose a method of image-guided brachytherapy (IGBT) that combines MRI-based target volume delineation for the first fraction with CT datasets of subsequent fractions, using an automatic, applicator-based co-registration, and report our preliminary experience. MATERIALS AND METHODS: The MRI of the first fraction was used for the first brachytherapy planning. For each subsequent brachytherapy fraction, after the same applicator insertion, a new CT scan with the applicator in place was obtained. The MR image set was registered to the subsequent brachytherapy treatment planning CT using the applicator for rigid body registration. To demonstrate the registration quality, we used here the Dice index as a measurement of tandem delineation overlap between CT and MRI. RESULTS: The median Dice index was 0.879 (range 0.610-0.932), which indicated that the contours on CT and MRI fitted well. With this combination method, the median D90 of HR CTV and the calculated D2 cm3 of the bladder, rectum, and sigmoid in each fraction were 7.2 (4.0-10.4), 5.9 (2.3-7.7), 4.0 (1.9-6.7), and 3.8 (0.6-7.2) Gy, respectively. CONCLUSION: Our described method of MRI-guided IGBT offers a practical option for the benefits of target delineation.
Authors: Richard Pötter; Christine Haie-Meder; Erik Van Limbergen; Isabelle Barillot; Marisol De Brabandere; Johannes Dimopoulos; Isabelle Dumas; Beth Erickson; Stefan Lang; An Nulens; Peter Petrow; Jason Rownd; Christian Kirisits Journal: Radiother Oncol Date: 2006-01-05 Impact factor: 6.280
Authors: Simon Pavamani; David P D'Souza; Lorraine Portelance; Peter S Craighead; Andrew G Pearce; Laurel L Traptow; Corinne M Doll Journal: Brachytherapy Date: 2011-02-23 Impact factor: 2.362
Authors: Christine Haie-Meder; Richard Pötter; Erik Van Limbergen; Edith Briot; Marisol De Brabandere; Johannes Dimopoulos; Isabelle Dumas; Taran Paulsen Hellebust; Christian Kirisits; Stefan Lang; Sabine Muschitz; Juliana Nevinson; An Nulens; Peter Petrow; Natascha Wachter-Gerstner Journal: Radiother Oncol Date: 2005-03 Impact factor: 6.280
Authors: Akila N Viswanathan; Johannes Dimopoulos; Christian Kirisits; Daniel Berger; Richard Pötter Journal: Int J Radiat Oncol Biol Phys Date: 2007-02-27 Impact factor: 7.038
Authors: Johannes C A Dimopoulos; Peter Petrow; Kari Tanderup; Primoz Petric; Daniel Berger; Christian Kirisits; Erik M Pedersen; Erik van Limbergen; Christine Haie-Meder; Richard Pötter Journal: Radiother Oncol Date: 2012-01-30 Impact factor: 6.280
Authors: Arun George Paul; Adrian Nalichowski; Judith Abrams; Peter Paximadis; Ling Zhuang; Steven Miller Journal: J Contemp Brachytherapy Date: 2018-06-28