Literature DB >> 29034128

Antibiotic sensitivity pattern of Klebsiella species in burn wounds at Bai Jerbai Wadia hospital for children, Mumbai, India-a 21 year study.

Shankar Srinivasan1, Jovita Saldanha2, Suhas Abhyankar3, Nikunj Modi4, Aakanksha Patil5, Arvind M Vartak6.   

Abstract

In our study, we attempt to look at the sensitivity pattern of the most commonly found microorganism in the wound swab of pediatric burn patients at our hospital, 'Klebsiella', to a number of commonly used antibiotics and to determine whether there has been a change in the sensitivities in the 21 year period between 1994 to 2014. The sensitivity was tested in vitro and antibiotics were administered to patients based on laboratory findings. Klebsiella shows a significant change in sensitivity pattern over last 21 years. The sensitivity of this organisms to various antibiotics tested has reduced over time. The organism out plays most of the antibiotics that it is subjected to in vitro. Our efforts should now be channelized towards limiting the use of antibiotics or a proper antibiotic policy which exercises control of irrelevant and excessive use of antibiotics.

Entities:  

Keywords:  Klebsiella; antibiotics; resistance

Year:  2017        PMID: 29034128      PMCID: PMC5636913     

Source DB:  PubMed          Journal:  Int J Burns Trauma        ISSN: 2160-2026


  10 in total

1.  Microbiologic aspects of predominant bacteria isolated from the burn patients in Korea.

Authors:  W Song; K M Lee; H J Kang; D H Shin; D K Kim
Journal:  Burns       Date:  2001-03       Impact factor: 2.744

Review 2.  Successful interventions for gram-negative resistance to extended-spectrum beta-lactam antiobiotics.

Authors:  L B Rice
Journal:  Pharmacotherapy       Date:  1999-08       Impact factor: 4.705

3.  Bacteriology of infected burn wounds in the burn wards of a teaching hospital in Southwest Nigeria.

Authors:  Idowu Olusegun Fadeyibi; Muhibat Adeola Raji; Nasiru Akanmu Ibrahim; Andrew Omotayo Ugburo; Samuel Ademiluyi
Journal:  Burns       Date:  2012-03-03       Impact factor: 2.744

4.  Antibiotic susceptibility testing by a standardized single disk method.

Authors:  A W Bauer; W M Kirby; J C Sherris; M Turck
Journal:  Am J Clin Pathol       Date:  1966-04       Impact factor: 2.493

Review 5.  Two decades of imipenem therapy.

Authors:  A C Rodloff; E J C Goldstein; A Torres
Journal:  J Antimicrob Chemother       Date:  2006-09-22       Impact factor: 5.790

6.  Bacteriology of burns at the Queen Elizabeth Central Hospital, Blantyre, Malawi.

Authors:  O O Komolafe; J James; L Kalongolera; M Makoka
Journal:  Burns       Date:  2003-05       Impact factor: 2.744

7.  Association of antibiotic utilization measures and control of multiple-drug resistance in Klebsiella pneumoniae.

Authors:  J E Patterson; T C Hardin; C A Kelly; R C Garcia; J H Jorgensen
Journal:  Infect Control Hosp Epidemiol       Date:  2000-07       Impact factor: 3.254

8.  Correlation of quantitative burn wound biopsy culture and surface swab culture to burn wound sepsis.

Authors:  R N Tahlan; R K Keswani; S Saini; O P Miglani
Journal:  Burns Incl Therm Inj       Date:  1984-02

9.  Bacteriology of the burn wound at the Bai Jerbai Wadia Hospital for children, Mumbai, India-A 13-year study, Part I-Bacteriological profile.

Authors:  Shankar Srinivasan; Arvind M Vartak; Aakanksha Patil; Jovita Saldanha
Journal:  Indian J Plast Surg       Date:  2009-07

10.  Class restriction of cephalosporin use to control total cephalosporin resistance in nosocomial Klebsiella.

Authors:  J J Rahal; C Urban; D Horn; K Freeman; S Segal-Maurer; J Maurer; N Mariano; S Marks; J M Burns; D Dominick; M Lim
Journal:  JAMA       Date:  1998-10-14       Impact factor: 56.272

  10 in total
  1 in total

1.  In vitro Antimicrobial Synergy Testing of Extensively Drug-Resistant Clinical Isolates at an Organ Transplant Center in Nepal.

Authors:  Rashmi Karki; Samir Lamichhane; Shyam Kumar Mishra; Buddha Bahadur Basnet; Anuja Dahal; Bal Krishna Awal
Journal:  Infect Drug Resist       Date:  2021-04-30       Impact factor: 4.003

  1 in total

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