Literature DB >> 29034036

Intervention for Varicose Veins of Lower Extremities Lowers the Brain Natriuretic Peptide Values in Varicose Vein Patients.

Kiyoshi Tamura1.   

Abstract

Objective: To evaluate the relationship between varicose veins and heart failure, both of which cause edema of lower extremities. Materials and
Methods: We enrolled 150 patients who underwent intervention for varicose veins of lower extremities between December 2012 and October 2015, and perioperative data were retrospectively investigated.
Results: Of the 150 patients, 104 (69.3%) were females. The mean age was 66.8±10.6 years (27-85 years). Eighty (53.3%) patients had varicose veins in both legs. In all patients, the postoperative (brain natriuretic peptide (BNP) value was significantly lower than the preoperative BNP value (pre : post=39.3 : 30.5 pg/dl, P<0.0001). In patients with higher BNP values (>100 pg/dl), the postoperative BNP values were significantly lower than the preoperative BNP values (pre : post=192.7 : 166.1 pg/dl, P<0.0001). Body weights of the patients decreased differently between pre- and post-operation (pre : post=61.3 : 59.4 kg, P=0.0008).
Conclusion: Intervention for varicose veins of lower extremities might be considered clinically useful for the improvement of cardiac function.

Entities:  

Keywords:  brain natriuretic peptide; heart failure; varicose vein

Year:  2017        PMID: 29034036      PMCID: PMC5579778          DOI: 10.3400/avd.oa.16-00102

Source DB:  PubMed          Journal:  Ann Vasc Dis        ISSN: 1881-641X


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1.  Log-transformed B-type natriuretic peptide as a prognostic predictor in patients undergoing cardiovascular surgery.

Authors:  Sho Takagi; Yuichiro Machida; Takashi Kobata; Daisuke Sakamoto; Shigeru Sakamoto; Tsugiyasu Kanda
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