Literature DB >> 29017278

Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever.

Vanessa N Raabe1, Gerrit Kann2, Bruce S Ribner1, Andres Morales3, Jay B Varkey1, Aneesh K Mehta1, G Marshall Lyon1, Sharon Vanairsdale4, Kelly Faber5, Stephan Becker6, Markus Eickmann6, Thomas Strecker6, Shelley Brown7, Ketan Patel7, Philipp De Leuw2, Gundolf Schuettfort2, Christoph Stephan2, Holger Rabenau8, John D Klena7, Pierre E Rollin7, Anita McElroy7, Ute Ströher7, Stuart Nichol7, Colleen S Kraft1,9, Timo Wolf2.   

Abstract

Two patients with Lassa fever are described who are the first human cases treated with a combination of ribavirin and favipiravir. Both patients survived but developed transaminitis and had prolonged detectable virus RNA in blood and semen, suggesting that the possibility of sexual transmission of Lassa virus should be considered.
© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Lassa; Togo; favipiravir; ribavirin

Mesh：

Substances：

Year:  2017        PMID： 29017278      PMCID： PMC5682919          DOI： 10.1093/cid/cix406

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  13 in total

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2.  RT-PCR assay for detection of Lassa virus and related Old World arenaviruses targeting the L gene.

Authors:  Simon Vieth; Christian Drosten; Oliver Lenz; Martin Vincent; Sunday Omilabu; Meike Hass; Beate Becker-Ziaja; Jan ter Meulen; Stuart T Nichol; Herbert Schmitz; Stephan Günther
Journal:  Trans R Soc Trop Med Hyg       Date:  2007-10-01       Impact factor: 2.184

3.  Absence of CTL responses to early viral antigens facilitates viral persistence.

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Journal:  Microbes Infect       Date:  2002-01       Impact factor: 2.700

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Authors:  Jay B Varkey; Jessica G Shantha; Ian Crozier; Colleen S Kraft; G Marshall Lyon; Aneesh K Mehta; Gokul Kumar; Justine R Smith; Markus H Kainulainen; Shannon Whitmer; Ute Ströher; Timothy M Uyeki; Bruce S Ribner; Steven Yeh
Journal:  N Engl J Med       Date:  2015-05-07       Impact factor: 91.245

6.  Lassa fever. Effective therapy with ribavirin.

Authors:  J B McCormick; I J King; P A Webb; C L Scribner; R B Craven; K M Johnson; L H Elliott; R Belmont-Williams
Journal:  N Engl J Med       Date:  1986-01-02       Impact factor: 91.245

7.  New Evidence of Long-lasting Persistence of Ebola Virus Genetic Material in Semen of Survivors.

Authors:  Mamadou S Sow; Jean-François Etard; Sylvain Baize; N'Fally Magassouba; Ousmane Faye; Philippe Msellati; Abdoulaye Touré; Ibrahima Savane; Moumié Barry; Eric Delaporte
Journal:  J Infect Dis       Date:  2016-05-03       Impact factor: 5.226

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Journal:  PLoS Med       Date:  2016-03-01       Impact factor: 11.069

10.  Efficacy of Favipiravir Alone and in Combination With Ribavirin in a Lethal, Immunocompetent Mouse Model of Lassa Fever.

Authors:  Lisa Oestereich; Toni Rieger; Anja Lüdtke; Paula Ruibal; Stephanie Wurr; Elisa Pallasch; Sabrina Bockholt; Susanne Krasemann; César Muñoz-Fontela; Stephan Günther
Journal:  J Infect Dis       Date:  2015-11-03       Impact factor: 5.226
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Authors:  Judith A Anesi; Fernanda P Silveira
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2.  A Highly Conserved Leucine in Mammarenavirus Matrix Z Protein Is Required for Z Interaction with the Virus L Polymerase and Z Stability in Cells Harboring an Active Viral Ribonucleoprotein.

Authors:  Masaharu Iwasaki; Juan C de la Torre
Journal:  J Virol       Date:  2018-05-14       Impact factor: 5.103

3.  What Pediatricians Should Know About Lassa Virus.

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6.  Effective Treatment of Experimental Lymphocytic Choriomeningitis Virus Infection: Consideration of Favipiravir for Use With Infected Organ Transplant Recipients.

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7.  Favipiravir Does Not Inhibit Chikungunya Virus Replication in Mosquito Cells and Aedes aegypti Mosquitoes.

Authors:  Sofie Jacobs; Lanjiao Wang; Ana Lucia Rosales Rosas; Ria Van Berwaer; Evelien Vanderlinden; Anna-Bella Failloux; Lieve Naesens; Leen Delang
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8.  A Case of Lassa Fever Diagnosed at a Community Hospital-Minnesota 2014.

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10.  Antiviral Efficacy of Ribavirin and Favipiravir against Hantaan Virus.

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