Literature DB >> 25950269

Persistence of Ebola Virus in Ocular Fluid during Convalescence.

Jay B Varkey1, Jessica G Shantha, Ian Crozier, Colleen S Kraft, G Marshall Lyon, Aneesh K Mehta, Gokul Kumar, Justine R Smith, Markus H Kainulainen, Shannon Whitmer, Ute Ströher, Timothy M Uyeki, Bruce S Ribner, Steven Yeh.   

Abstract

Among the survivors of Ebola virus disease (EVD), complications that include uveitis can develop during convalescence, although the incidence and pathogenesis of EVD-associated uveitis are unknown. We describe a patient who recovered from EVD and was subsequently found to have severe unilateral uveitis during convalescence. Viable Zaire ebolavirus (EBOV) was detected in aqueous humor 14 weeks after the onset of EVD and 9 weeks after the clearance of viremia.

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Year:  2015        PMID: 25950269      PMCID: PMC4547451          DOI: 10.1056/NEJMoa1500306

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


  11 in total

1.  Successful delivery of RRT in Ebola virus disease.

Authors:  Michael J Connor; Colleen Kraft; Aneesh K Mehta; Jay B Varkey; G Marshall Lyon; Ian Crozier; Ute Ströher; Bruce S Ribner; Harold A Franch
Journal:  J Am Soc Nephrol       Date:  2014-11-14       Impact factor: 10.121

2.  Laboratory test support for Ebola patients within a high-containment facility.

Authors:  Charles E Hill; Eileen M Burd; Colleen S Kraft; Emily L Ryan; Alexander Duncan; Anne M Winkler; John C Cardella; James C Ritchie; Tristram G Parslow
Journal:  Lab Med       Date:  2014

3.  Uveal involvement in Marburg virus disease.

Authors:  B S Kuming; N Kokoris
Journal:  Br J Ophthalmol       Date:  1977-04       Impact factor: 4.638

4.  Herpes simplex virus in the trabeculum of an eye with corneal endotheliitis.

Authors:  S Amano; T Oshika; Y Kaji; J Numaga; M Matsubara; M Araie
Journal:  Am J Ophthalmol       Date:  1999-06       Impact factor: 5.258

5.  Clinical, virologic, and immunologic follow-up of convalescent Ebola hemorrhagic fever patients and their household contacts, Kikwit, Democratic Republic of the Congo. Commission de Lutte contre les Epidémies à Kikwit.

Authors:  A K Rowe; J Bertolli; A S Khan; R Mukunu; J J Muyembe-Tamfum; D Bressler; A J Williams; C J Peters; L Rodriguez; H Feldmann; S T Nichol; P E Rollin; T G Ksiazek
Journal:  J Infect Dis       Date:  1999-02       Impact factor: 5.226

6.  Late ophthalmologic manifestations in survivors of the 1995 Ebola virus epidemic in Kikwit, Democratic Republic of the Congo.

Authors:  K Kibadi; K Mupapa; K Kuvula; M Massamba; D Ndaberey; J J Muyembe-Tamfum; M A Bwaka; A De Roo; R Colebunders
Journal:  J Infect Dis       Date:  1999-02       Impact factor: 5.226

7.  Outbreake of Marburg virus disease in Johannesburg.

Authors:  J S Gear; G A Cassel; A J Gear; B Trappler; L Clausen; A M Meyers; M C Kew; T H Bothwell; R Sher; G B Miller; J Schneider; H J Koornhof; E D Gomperts; M Isaäcson; J H Gear
Journal:  Br Med J       Date:  1975-11-29

8.  Clinical features of cytomegalovirus anterior uveitis in immunocompetent patients.

Authors:  Soon-Phaik Chee; Kristine Bacsal; Aliza Jap; Su-Yun Se-Thoe; Ching Li Cheng; Ban Hock Tan
Journal:  Am J Ophthalmol       Date:  2008-02-06       Impact factor: 5.258

9.  The Use of TKM-100802 and Convalescent Plasma in 2 Patients With Ebola Virus Disease in the United States.

Authors:  Colleen S Kraft; Angela L Hewlett; Scott Koepsell; Anne M Winkler; Christopher J Kratochvil; LuAnn Larson; Jay B Varkey; Aneesh K Mehta; G Marshall Lyon; Rachel J Friedman-Moraco; Vincent C Marconi; Charles E Hill; James N Sullivan; Daniel W Johnson; Steven J Lisco; Mark J Mulligan; Timothy M Uyeki; Anita K McElroy; Tara Sealy; Shelley Campbell; Christina Spiropoulou; Ute Ströher; Ian Crozier; Richard Sacra; Michael J Connor; Viranuj Sueblinvong; Harold A Franch; Philip W Smith; Bruce S Ribner
Journal:  Clin Infect Dis       Date:  2015-04-22       Impact factor: 9.079

10.  Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak.

Authors:  Stephen K Gire; Augustine Goba; Kristian G Andersen; Rachel S G Sealfon; Daniel J Park; Lansana Kanneh; Simbirie Jalloh; Mambu Momoh; Mohamed Fullah; Gytis Dudas; Shirlee Wohl; Lina M Moses; Nathan L Yozwiak; Sarah Winnicki; Christian B Matranga; Christine M Malboeuf; James Qu; Adrianne D Gladden; Stephen F Schaffner; Xiao Yang; Pan-Pan Jiang; Mahan Nekoui; Andres Colubri; Moinya Ruth Coomber; Mbalu Fonnie; Alex Moigboi; Michael Gbakie; Fatima K Kamara; Veronica Tucker; Edwin Konuwa; Sidiki Saffa; Josephine Sellu; Abdul Azziz Jalloh; Alice Kovoma; James Koninga; Ibrahim Mustapha; Kandeh Kargbo; Momoh Foday; Mohamed Yillah; Franklyn Kanneh; Willie Robert; James L B Massally; Sinéad B Chapman; James Bochicchio; Cheryl Murphy; Chad Nusbaum; Sarah Young; Bruce W Birren; Donald S Grant; John S Scheiffelin; Eric S Lander; Christian Happi; Sahr M Gevao; Andreas Gnirke; Andrew Rambaut; Robert F Garry; S Humarr Khan; Pardis C Sabeti
Journal:  Science       Date:  2014-08-28       Impact factor: 47.728

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  170 in total

Review 1.  Clinical development of Ebola vaccines.

Authors:  Saranya Sridhar
Journal:  Ther Adv Vaccines       Date:  2015-09

2.  Apheresis for collection of Ebola convalescent plasma in Liberia.

Authors:  Jerry F Brown; Kathleen Rowe; Peter Zacharias; James van Hasselt; John M Dye; David A Wohl; William A Fischer; Coleen K Cunningham; Nathan M Thielman; David L Hoover
Journal:  J Clin Apher       Date:  2016-07-08       Impact factor: 2.821

3.  Longitudinal peripheral blood transcriptional analysis of a patient with severe Ebola virus disease.

Authors:  John C Kash; Kathie-Anne Walters; Jason Kindrachuk; David Baxter; Kelsey Scherler; Krisztina B Janosko; Rick D Adams; Andrew S Herbert; Rebekah M James; Spencer W Stonier; Matthew J Memoli; John M Dye; Richard T Davey; Daniel S Chertow; Jeffery K Taubenberger
Journal:  Sci Transl Med       Date:  2017-04-12       Impact factor: 17.956

4.  Identification and pathological characterization of persistent asymptomatic Ebola virus infection in rhesus monkeys.

Authors:  Xiankun Zeng; Candace D Blancett; Keith A Koistinen; Christopher W Schellhase; Jeremy J Bearss; Sheli R Radoshitzky; Shelley P Honnold; Taylor B Chance; Travis K Warren; Jeffrey W Froude; Kathleen A Cashman; John M Dye; Sina Bavari; Gustavo Palacios; Jens H Kuhn; Mei G Sun
Journal:  Nat Microbiol       Date:  2017-07-17       Impact factor: 17.745

5.  Cataract management in Ebola virus disease survivors: clinical and scientific implications.

Authors:  Alexa L Li; Duncan E Berry; Jessica G Shantha; Steven Yeh
Journal:  Future Virol       Date:  2019-01-21       Impact factor: 1.831

Review 6.  Insights from clinical research completed during the west Africa Ebola virus disease epidemic.

Authors:  Amanda Rojek; Peter Horby; Jake Dunning
Journal:  Lancet Infect Dis       Date:  2017-04-28       Impact factor: 25.071

Review 7.  The Eyes Have it: A Rheumatologist's View of Uveitis.

Authors:  James T Rosenbaum; Andrew D Dick
Journal:  Arthritis Rheumatol       Date:  2018-08-23       Impact factor: 10.995

8.  Ebola virus and persistent chronic infection: when does replication cease?

Authors:  John V Forrester
Journal:  Ann Transl Med       Date:  2018-11

9.  Infectious Uveitis.

Authors:  Phoebe Lin
Journal:  Curr Ophthalmol Rep       Date:  2015-06-13

10.  Necrotizing Scleritis, Conjunctivitis, and Other Pathologic Findings in the Left Eye and Brain of an Ebola Virus-Infected Rhesus Macaque (Macaca mulatta) With Apparent Recovery and a Delayed Time of Death.

Authors:  Derron A Alves; Anna N Honko; Mark G Kortepeter; Mei Sun; Joshua C Johnson; Luis A Lugo-Roman; Lisa E Hensley
Journal:  J Infect Dis       Date:  2015-07-07       Impact factor: 5.226

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