Literature DB >> 27045122

Ebola Virus Persistence in Semen of Male Survivors.

Timothy M Uyeki1, Bobbie Rae Erickson1, Shelley Brown1, Anita K McElroy1,2, Deborah Cannon1, Aridth Gibbons1, Tara Sealy1, Markus H Kainulainen1, Amy J Schuh1, Colleen S Kraft2, Aneesh K Mehta2, G Marshall Lyon2, Jay B Varkey2, Bruce S Ribner2, Richard T Ellison3, Ellie Carmody4, Gerard J Nau5, Christina Spiropoulou1, Stuart T Nichol1, Ute Ströher1.   

Abstract

We investigated the duration of Ebola virus (EBOV) RNA and infectious EBOV in semen specimens of 5 Ebola virus disease (EVD) survivors. EBOV RNA and infectious EBOV was detected by real-time RT-PCR and virus culture out to 290 days and 70 days, respectively, after EVD onset. Published by Oxford University Press for the Infectious Diseases Society of America 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Entities:  

Keywords:  Ebola virus; semen; sexual transmission

Mesh:

Year:  2016        PMID: 27045122     DOI: 10.1093/cid/ciw202

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  52 in total

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Journal:  N Engl J Med       Date:  2019-03-07       Impact factor: 91.245

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Journal:  J Infect Dis       Date:  2020-10-01       Impact factor: 5.226

8.  A Case of Human Lassa Virus Infection With Robust Acute T-Cell Activation and Long-Term Virus-Specific T-Cell Responses.

Authors:  Anita K McElroy; Rama S Akondy; Jessica R Harmon; Ali H Ellebedy; Deborah Cannon; John D Klena; John Sidney; Alessandro Sette; Aneesh K Mehta; Colleen S Kraft; Marshall G Lyon; Jay B Varkey; Bruce S Ribner; Stuart T Nichol; Christina F Spiropoulou
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9.  Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.

Authors:  Priya Luthra; Jacinth Naidoo; Colette A Pietzsch; Sampriti De; Sudip Khadka; Manu Anantpadma; Caroline G Williams; Megan R Edwards; Robert A Davey; Alexander Bukreyev; Joseph M Ready; Christopher F Basler
Journal:  Antiviral Res       Date:  2018-08-23       Impact factor: 5.970

10.  Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA.

Authors:  Emily P Thi; Amy C H Lee; Joan B Geisbert; Raul Ursic-Bedoya; Krystle N Agans; Marjorie Robbins; Daniel J Deer; Karla A Fenton; Andrew S Kondratowicz; Ian MacLachlan; Thomas W Geisbert; Chad E Mire
Journal:  Nat Microbiol       Date:  2016-08-22       Impact factor: 17.745

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