| Literature DB >> 28993338 |
Romney M Humphries1, Janet A Hindler2, Annie Wong-Beringer3,4, Shelley A Miller2.
Abstract
Ceftolozane-tazobactam (C/T) and ceftazidime-avibactam (CZA) MICs were evaluated for a collection of 309 beta-lactam-resistant isolates of Pseudomonas aeruginosa recovered from three institutions in the area of Los Angeles, CA. Overall, 12.0% of isolates were susceptible to imipenem, 15.9% were susceptible to meropenem, 20.7% were susceptible to piperacillin-tazobactam, 24.6% were susceptible to ceftazidime, 25.9% were susceptible to cefepime, 72.5% were susceptible to C/T, and 61.8% were susceptible to CZA. Among C/T-resistant isolates, 9.1% were CZA susceptible, whereas 36.4% of CZA-resistant isolates were susceptible to C/T.Entities:
Keywords: MIC; Pseudomonas aeruginosa; ceftazidime-avibactam; ceftolozane-tazobactam; susceptibility testing
Mesh:
Substances:
Year: 2017 PMID: 28993338 PMCID: PMC5700315 DOI: 10.1128/AAC.01858-17
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191