BACKGROUND: Breast cancer is the most common female malignancy worldwide. The aim of this study was to investigate the influence of surgical procedures and quality-of-care (QoC) on quality-of-life (QoL) among breast cancer survivors who underwent breast-conserving therapy (BCT) or mastectomy, and to identify provider- and patient-related factors pertaining to QoL. METHOD: In this cross-sectional study, structured-questionnaires were distributed among breast cancer survivors in 19 hospitals. QoL was evaluated using the European Organization for Research and Treatment of Cancer core questionnaire (EORTC QLQ-C30) and the breast cancer specific module (EORTC QLQ-BR23). QoC is indicated by adherence to the core measures stipulated for the treatment of breast cancer. Multiple regression and hierarchical linear modeling were used for multivariate analysis. RESULTS: A total of 544 female survivors of Stage 0-III breast cancer were included, among whom 217 (39.9%) underwent BCT and 327 (60.1%) underwent mastectomy. Surgical modality does not appear to have a notable impact on any QoL domains except body image; i.e. patients who underwent BCT reported better body image (diff = 11.20, P < 0.001), particularly at 1-5 years after the initial treatment. Independent factors including age, education, employment, marital status, income, chemotherapy, duration since treatment, recurrence status, primary hospital accreditation level and location all appear to be correlated to QoL. CONCLUSION: Patients with breast cancer should be informed of differences in QoL when discussing treatment options. Furthermore, physicians should recognize that the impact of surgical treatment modality on QoL may vary according to patients' sociodemographic and clinical characteristics.
BACKGROUND: Breast cancer is the most common female malignancy worldwide. The aim of this study was to investigate the influence of surgical procedures and quality-of-care (QoC) on quality-of-life (QoL) among breast cancer survivors who underwent breast-conserving therapy (BCT) or mastectomy, and to identify provider- and patient-related factors pertaining to QoL. METHOD: In this cross-sectional study, structured-questionnaires were distributed among breast cancer survivors in 19 hospitals. QoL was evaluated using the European Organization for Research and Treatment of Cancer core questionnaire (EORTC QLQ-C30) and the breast cancer specific module (EORTC QLQ-BR23). QoC is indicated by adherence to the core measures stipulated for the treatment of breast cancer. Multiple regression and hierarchical linear modeling were used for multivariate analysis. RESULTS: A total of 544 female survivors of Stage 0-III breast cancer were included, among whom 217 (39.9%) underwent BCT and 327 (60.1%) underwent mastectomy. Surgical modality does not appear to have a notable impact on any QoL domains except body image; i.e. patients who underwent BCT reported better body image (diff = 11.20, P < 0.001), particularly at 1-5 years after the initial treatment. Independent factors including age, education, employment, marital status, income, chemotherapy, duration since treatment, recurrence status, primary hospital accreditation level and location all appear to be correlated to QoL. CONCLUSION: Patients with breast cancer should be informed of differences in QoL when discussing treatment options. Furthermore, physicians should recognize that the impact of surgical treatment modality on QoL may vary according to patients' sociodemographic and clinical characteristics.
Authors: Mirelle Lagendijk; Elizabeth Mittendorf; Tari A King; Christopher Gibbons; Andrea Pusic; Laura S Dominici Journal: Oncologist Date: 2019-12-17
Authors: Paulina Bajonero-Canonico; Ana S Ferrigno; Jorge A Saldaña-Rodriguez; David E Hinojosa-Gonzalez; Cristel G de la O-Maldonado; Carlos de la Cruz-de la Cruz; Brizio Moreno-Jaime; Mariela Hernandez-Pavon; Jose Moral-de la Rubia; Melina Miaja-Avila; Cynthia Villarreal-Garza Journal: Support Care Cancer Date: 2020-09-25 Impact factor: 3.603
Authors: Delphine Lefeuvre; Nathalie Catajar; Christine Le Bihan Benjamin; Norbert Ifrah; Frédéric De Bels; Jérôme Viguier; Philippe Jean Bousquet Journal: Cancer Med Date: 2019-06-06 Impact factor: 4.452
Authors: Alberto Carmona-Bayonas; Caterina Calderón; Raquel Hernández; Ana Fernández Montes; Beatriz Castelo; Laura Ciria-Suarez; Mónica Antoñanzas; Jacobo Rogado; Vilma Pacheco-Barcia; Elena Asensio Martínez; Alejandra Ivars; Francisco Ayala de la Peña; Paula Jimenez-Fonseca Journal: NPJ Breast Cancer Date: 2021-07-13