Literature DB >> 28974517

What Do We Really Think About Human Germline Genome Editing, and What Does It Mean for Medicine?

Kiran Musunuru1, William R Lagor2, Joseph M Miano2.   

Abstract

Entities:  

Keywords:  American Heart Association; gene editing; genetics; mosaicism; mutation

Mesh：

Year:  2017        PMID： 28974517      PMCID： PMC5658039          DOI： 10.1161/CIRCGENETICS.117.001910

Source DB:  PubMed          Journal:  Circ Cardiovasc Genet        ISSN： 1942-3268


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  6 in total

Review 1.  Human Germline Genome Editing.

Authors:  Kelly E Ormond; Douglas P Mortlock; Derek T Scholes; Yvonne Bombard; Lawrence C Brody; W Andrew Faucett; Nanibaa' A Garrison; Laura Hercher; Rosario Isasi; Anna Middleton; Kiran Musunuru; Daniel Shriner; Alice Virani; Caroline E Young
Journal:  Am J Hum Genet       Date:  2017-08-03       Impact factor: 11.025

Review 2.  A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research.

Authors:  Joseph M Miano; Qiuyu Martin Zhu; Charles J Lowenstein
Journal:  Arterioscler Thromb Vasc Biol       Date:  2016-04-21       Impact factor: 8.311

3.  Correction of a pathogenic gene mutation in human embryos.

Authors:  Hong Ma; Nuria Marti-Gutierrez; Sang-Wook Park; Jun Wu; Yeonmi Lee; Keiichiro Suzuki; Amy Koski; Dongmei Ji; Tomonari Hayama; Riffat Ahmed; Hayley Darby; Crystal Van Dyken; Ying Li; Eunju Kang; A-Reum Park; Daesik Kim; Sang-Tae Kim; Jianhui Gong; Ying Gu; Xun Xu; David Battaglia; Sacha A Krieg; David M Lee; Diana H Wu; Don P Wolf; Stephen B Heitner; Juan Carlos Izpisua Belmonte; Paula Amato; Jin-Soo Kim; Sanjiv Kaul; Shoukhrat Mitalipov
Journal:  Nature       Date:  2017-08-02       Impact factor: 49.962

4.  In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing.

Authors:  Alexandra C Chadwick; Xiao Wang; Kiran Musunuru
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-07-27       Impact factor: 8.311

5.  Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing.

Authors:  Qiurong Ding; Alanna Strong; Kevin M Patel; Sze-Ling Ng; Bridget S Gosis; Stephanie N Regan; Chad A Cowan; Daniel J Rader; Kiran Musunuru
Journal:  Circ Res       Date:  2014-06-10       Impact factor: 17.367

6.  Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease.

Authors:  Kelsey E Jarrett; Ciaran M Lee; Yi-Hsien Yeh; Rachel H Hsu; Rajat Gupta; Min Zhang; Perla J Rodriguez; Chang Seok Lee; Baiba K Gillard; Karl-Dimiter Bissig; Henry J Pownall; James F Martin; Gang Bao; William R Lagor
Journal:  Sci Rep       Date:  2017-03-16       Impact factor: 4.379
  6 in total
  3 in total

1.  Attitudes of clinical geneticists and certified genetic counselors to genome editing and its clinical applications: A nation-wide questionnaire survey in Japan.

Authors:  Iku Taguchi; Takahiro Yamada; Rina Akaishi; Issei Imoto; Kenji Kurosawa; Kaname Nakatani; Fumio Nomura; Haruka Hamanoue; Maki Hyodo; Hiromi Murakami; Hiroshi Yoshihashi; Junko Yotsumoto; Shinji Kosugi
Journal:  J Hum Genet       Date:  2019-07-05       Impact factor: 3.172

Review 2.  Genome Editing: The Recent History and Perspective in Cardiovascular Diseases.

Authors:  Kiran Musunuru
Journal:  J Am Coll Cardiol       Date:  2017-12-05       Impact factor: 24.094

3.  Predicting Public Attitudes Toward Gene Editing of Germlines: The Impact of Moral and Hereditary Concern in Human and Animal Applications.

Authors:  Christine Critchley; Dianne Nicol; Gordana Bruce; Jarrod Walshe; Tamara Treleaven; Bernard Tuch
Journal:  Front Genet       Date:  2019-01-09       Impact factor: 4.599
  3 in total

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