Alicia A Heelan Gladden1, Sharon Sams2, Ana Gleisner3, Christina Finlayson4, Nicole Kounalakis5, Patrick Hosokawa6, Regina Brown7, Tae Chong8, David Mathes9, Colleen Murphy10. 1. University of Colorado School of Medicine, Department of Surgery, Aurora, CO, USA. Electronic address: Alicia.heelangladden@ucdenver.edu. 2. University of Colorado School of Medicine, Department of Pathology, Aurora, CO, USA. Electronic address: Sharon.Sams@ucdenver.edu. 3. University of Colorado School of Medicine, Department of Surgery, Aurora, CO, USA. Electronic address: Ana.gleisner@ucdenver.edu. 4. University of Colorado School of Medicine, Department of Surgery, Aurora, CO, USA. Electronic address: Christina.Finlayson@ucdenver.edu. 5. University of Colorado School of Medicine, Department of Surgery, Aurora, CO, USA. Electronic address: Nicole.Kounalakis@ucdenver.edu. 6. Accords, Aurora, CO, USA. Electronic address: Patrick.Hosokawa@ucdenver.edu. 7. University of Colorado School of Medicine, Department of Oncology, Lone Tree, CO, USA. Electronic address: Regina.Brown@ucdenver.edu. 8. University of Colorado School of Medicine, Department of Surgery, Division of Plastic & Reconstructive Surgery, Aurora, CO, USA. Electronic address: Tae.Chong@ucdenver.edu. 9. University of Colorado School of Medicine, Department of Surgery, Division of Plastic & Reconstructive Surgery, Aurora, CO, USA. Electronic address: David.Mathes@ucdenver.edu. 10. University of Colorado School of Medicine, Department of Surgery, Aurora, CO, USA. Electronic address: Colleen.d.murphy@ucdenver.edu.
Abstract
BACKGROUND: In 2014, SSO-ASTRO published guidelines which recommended "no ink on tumor" as adequate margins for patients undergoing breast conservation for invasive breast cancer. In 2016, new SSO-ASTRO-ASCO guidelines recommended 2 mm margins for DCIS. We evaluated whether these guidelines affected re-excision rates at our institution. METHODS: Patients treated with breast conservation surgery from January 1, 2010-March 1, 2016 were identified. Re-excision rates, tumor characteristics, and presence of residual disease were recorded. The 2016 guidelines were retrospectively applied to the same cohort and expected re-excision rates calculated. RESULTS: Re-excision rates did not significantly decline before and after 2014 guideline adoption (11.9% before, 10.9% after; p = 0.65) or when the 2016 guidelines were retrospectively applied (8.4%; p = 0.10). CONCLUSIONS: The 2014 and 2016 guidelines had minimal impact on our re-excision rates, as most re-excisions were done for DCIS and 2016 guidelines supported our prior institutional practices of 2 mm margins for these patients.
BACKGROUND: In 2014, SSO-ASTRO published guidelines which recommended "no ink on tumor" as adequate margins for patients undergoing breast conservation for invasive breast cancer. In 2016, new SSO-ASTRO-ASCO guidelines recommended 2 mm margins for DCIS. We evaluated whether these guidelines affected re-excision rates at our institution. METHODS:Patients treated with breast conservation surgery from January 1, 2010-March 1, 2016 were identified. Re-excision rates, tumor characteristics, and presence of residual disease were recorded. The 2016 guidelines were retrospectively applied to the same cohort and expected re-excision rates calculated. RESULTS: Re-excision rates did not significantly decline before and after 2014 guideline adoption (11.9% before, 10.9% after; p = 0.65) or when the 2016 guidelines were retrospectively applied (8.4%; p = 0.10). CONCLUSIONS: The 2014 and 2016 guidelines had minimal impact on our re-excision rates, as most re-excisions were done for DCIS and 2016 guidelines supported our prior institutional practices of 2 mm margins for these patients.
Authors: Winona L Richey; Jon S Heiselman; Ma Luo; Ingrid M Meszoely; Michael I Miga Journal: Int J Comput Assist Radiol Surg Date: 2021-08-12 Impact factor: 3.421
Authors: Kathryn Ottolino-Perry; Anam Shahid; Stephanie DeLuca; Viktor Son; Mayleen Sukhram; Fannong Meng; Zhihui Amy Liu; Sara Rapic; Nayana Thalanki Anantha; Shirley C Wang; Emilie Chamma; Christopher Gibson; Philip J Medeiros; Safa Majeed; Ashley Chu; Olivia Wignall; Alessandra Pizzolato; Cheryl F Rosen; Liis Lindvere Teene; Danielle Starr-Dunham; Iris Kulbatski; Tony Panzarella; Susan J Done; Alexandra M Easson; Wey L Leong; Ralph S DaCosta Journal: Breast Cancer Res Date: 2021-07-12 Impact factor: 6.466