Literature DB >> 28965641

Severe Delayed Drug Reactions: Role of Genetics and Viral Infections.

Rebecca Pavlos1, Katie D White2, Celestine Wanjalla2, Simon A Mallal3, Elizabeth J Phillips4.   

Abstract

Adverse drug reactions (ADRs) are a significant source of patient morbidity and mortality and represent a major burden to health care systems and drug development. Up to 50% of such reactions are preventable. Although many ADRs can be predicted based on the on-target pharmacologic activity, ADRs arising from drug interactions with off-target receptors are recognized. Off-target ADRs include the immune-mediated ADRs (IM-ADRs) and pharmacologic drug effects. In this review, we discuss what is known about the immunogenetics and pathogenesis of IM-ADRs and the hypothesized role of heterologous immunity in the development of IM-ADRs.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Adverse drug reaction; Drug reaction with eosinophilia and systemic symptoms; Human herpes virus; Human leukocyte antigen; Pharmacogenomics; Steven Johnson syndrome; T-cell receptor; Toxic epidermal necrolysis

Mesh：

Substances：

Year:  2017        PMID： 28965641      PMCID： PMC5702581          DOI： 10.1016/j.iac.2017.07.007

Source DB:  PubMed          Journal:  Immunol Allergy Clin North Am        ISSN： 0889-8561            Impact factor:   3.479


  210 in total

1.  DRESS syndrome caused by teicoplanin and vancomycin, associated with reactivation of human herpesvirus-6.

Authors:  Risa Tamagawa-Mineoka; Norito Katoh; Takeshi Nara; Yukihide Nishimura; Satoshi Yamamoto; Saburo Kishimoto
Journal:  Int J Dermatol       Date:  2007-06       Impact factor: 2.736

2.  External quality assessment of HLA-B*5701 reporting: an international multicentre survey.

Authors:  Emma Hammond; Coral-Ann Almeida; Cyril Mamotte; David Nolan; Elizabeth Phillips; Tineke Asma Schollaardt; M John Gill; Jonathan B Angel; Doris Neurath; Jianping Li; Tony Giulivi; Cathy McIntyre; Galina Koultchitski; Betty Wong; Marciano Reis; Anita Rachlis; David E Cole; Choo Beng Chew; Stefan Neifer; Richard Lalonde; Michel Roger; Annie Jeanneau; Simon Mallal
Journal:  Antivir Ther       Date:  2007

Review 3.  The phenotype standardization project: improving pharmacogenetic studies of serious adverse drug reactions.

Authors:  M Pirmohamed; G P Aithal; E Behr; A Daly; D Roden
Journal:  Clin Pharmacol Ther       Date:  2011-06       Impact factor: 6.875

4.  Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population.

Authors:  Pär Hallberg; Niclas Eriksson; Luisa Ibañez; Emmanuelle Bondon-Guitton; Reinhold Kreutz; Alfonso Carvajal; M Isabel Lucena; Esther Sancho Ponce; Mariam Molokhia; Javier Martin; Tomas Axelsson; Qun-Ying Yue; Patrik K E Magnusson; Mia Wadelius
Journal:  Lancet Diabetes Endocrinol       Date:  2016-05-03       Impact factor: 32.069

Review 5.  DRESS syndrome in a patient on sulfasalazine for rheumatoid arthritis.

Authors:  Fabrice Michel; Jean-Christophe Navellou; Denis Ferraud; Eric Toussirot; Daniel Wendling
Journal:  Joint Bone Spine       Date:  2005-01       Impact factor: 4.929

6.  Genetic variations in HLA-B region and hypersensitivity reactions to abacavir.

Authors:  Seth Hetherington; Arlene R Hughes; Michael Mosteller; Denise Shortino; Katherine L Baker; William Spreen; Eric Lai; Kirstie Davies; Abigail Handley; David J Dow; Mary E Fling; Michael Stocum; Clive Bowman; Linda M Thurmond; Allen D Roses
Journal:  Lancet       Date:  2002-03-30       Impact factor: 79.321

7.  Positive and negative associations of HLA class I alleles with allopurinol-induced SCARs in Koreans.

Authors:  Hye-Ryun Kang; Young Koo Jee; Yon-Soo Kim; Chang Hwa Lee; Jae-Woo Jung; Sae Hoon Kim; Heung-Woo Park; Yoon-Seok Chang; In-Jin Jang; Sang-Heon Cho; Kyung-Up Min; Sang-Heon Kim; Kyung Wha Lee
Journal:  Pharmacogenet Genomics       Date:  2011-05       Impact factor: 2.089

Review 8.  No one is naive: the significance of heterologous T-cell immunity.

Authors:  Raymond M Welsh; Liisa K Selin
Journal:  Nat Rev Immunol       Date:  2002-06       Impact factor: 53.106

Review 9.  Hospital admissions associated with adverse drug reactions: a systematic review of prospective observational studies.

Authors:  Chuenjid Kongkaew; Peter R Noyce; Darren M Ashcroft
Journal:  Ann Pharmacother       Date:  2008-07-01       Impact factor: 3.154

10.  Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population.

Authors:  Daniel F Carr; Mas Chaponda; Andrea L Jorgensen; Elena Cornejo Castro; Joep J van Oosterhout; Saye H Khoo; David G Lalloo; Robert S Heyderman; Ana Alfirevic; Munir Pirmohamed
Journal:  Clin Infect Dis       Date:  2013-01-29       Impact factor: 9.079
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  11 in total

Review 1.  Controversies in drug allergy: Testing for delayed reactions.

Authors:  Elizabeth J Phillips; Paul Bigliardi; Andreas J Bircher; Ana Broyles; Yoon-Seok Chang; Wen-Hung Chung; Rannakoe Lehloenya; Maja Mockenhaupt; Jonny Peter; Munir Pirmohamed; Jean-Claude Roujeau; Neil H Shear; Luciana Kase Tanno; Jason Trubiano; Rocco Valluzzi; Annick Barbaud
Journal:  J Allergy Clin Immunol       Date:  2018-12-17       Impact factor: 10.793

2.  An atypical presentation of toxic epidermal necrolysis without mucosal involvement.

Authors:  Vikas Pathania; Sukriti Baveja; Anwita Sinha; J K Bhatia
Journal:  Med J Armed Forces India       Date:  2019-12-16

3.  Drug-Induced Hypersensitivity Syndrome (DIHS)/Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): Clinical Features and Pathogenesis.

Authors:  Natsumi Hama; Riichiro Abe; Andrew Gibson; Elizabeth J Phillips
Journal:  J Allergy Clin Immunol Pract       Date:  2022-02-15

Review 4.  Adaptive immune cells in calcific aortic valve disease.

Authors:  Michael A Raddatz; Meena S Madhur; W David Merryman
Journal:  Am J Physiol Heart Circ Physiol       Date:  2019-05-03       Impact factor: 4.733

5.  NEW STRATEGIES TO PREDICT AND PREVENT SERIOUS IMMUNOLOGICALLY MEDIATED ADVERSE DRUG REACTIONS.

Authors:  Elizabeth J Phillips
Journal:  Trans Am Clin Climatol Assoc       Date:  2018

6.  Delabeling Delayed Drug Hypersensitivity: How Far Can You Safely Go?

Authors:  Rannakoe J Lehloenya; Jonny G Peter; Ana Copascu; Jason A Trubiano; Elizabeth J Phillips
Journal:  J Allergy Clin Immunol Pract       Date:  2020-10

Review 7.  Mechanisms of Severe Cutaneous Adverse Reactions: Recent Advances.

Authors:  Teresa Bellón
Journal:  Drug Saf       Date:  2019-08       Impact factor: 5.228

8.  Clinical features, outcomes and treatment in children with drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis.

Authors:  Lucia Liotti; Silvia Caimmi; Paolo Bottau; Roberto Bernardini; Fabio Cardinale; Francesca Saretta; Francesca Mori; Giuseppe Crisafulli; Fabrizio Franceschini; Carlo Caffarelli
Journal:  Acta Biomed       Date:  2019-01-29

Review 9.  Applications of Immunopharmacogenomics: Predicting, Preventing, and Understanding Immune-Mediated Adverse Drug Reactions.

Authors:  Jason H Karnes; Matthew A Miller; Katie D White; Katherine C Konvinse; Rebecca K Pavlos; Alec J Redwood; Jonathan G Peter; Rannakoe Lehloenya; Simon A Mallal; Elizabeth J Phillips
Journal:  Annu Rev Pharmacol Toxicol       Date:  2018-08-22       Impact factor: 13.820

Review 10.  [Three keys to the appropriate choice of oral antibiotic treatment in the respiratory tract infections].

Authors:  R Menéndez; R Cantón; A García-Caballero; J Barberán
Journal:  Rev Esp Quimioter       Date:  2019-12-04       Impact factor: 1.553
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