Literature DB >> 35035053

An atypical presentation of toxic epidermal necrolysis without mucosal involvement.

Vikas Pathania1, Sukriti Baveja2, Anwita Sinha3, J K Bhatia4.   

Abstract

Toxic epidermal necrolysis (TEN) is a severe adverse cutaneous drug reaction with ubiquitous involvement of mucosa. Drugs are identified as the main etiology in most cases. Cutaneous involvement in TEN occurs in the form of widespread painful erythematous macules, targetoid lesions, full-thickness or focal epidermal necrosis, whereas mucosal involvement involves oral, genital, and ocular mucous membranes along with preceding prodromal flu-like symptoms. Atypical presentations include involvement of only mucosa without involvement of skin. We report a rare case of TEN without any mucosal involvement.
© 2019 Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd.

Entities:  

Keywords:  Itraconazole; Mucosal involvement; Toxic epidermal necrolysis

Year:  2019        PMID: 35035053      PMCID: PMC8737111          DOI: 10.1016/j.mjafi.2019.10.003

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  12 in total

1.  Toxic epidermal necrolysis: an eruption resembling scalding of the skin.

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Journal:  Br J Dermatol       Date:  1956-11       Impact factor: 9.302

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Journal:  J Am Acad Dermatol       Date:  2007-02       Impact factor: 11.527

4.  ALDEN, an algorithm for assessment of drug causality in Stevens-Johnson Syndrome and toxic epidermal necrolysis: comparison with case-control analysis.

Authors:  B Sassolas; C Haddad; M Mockenhaupt; A Dunant; Y Liss; K Bork; U F Haustein; D Vieluf; J C Roujeau; H Le Louet
Journal:  Clin Pharmacol Ther       Date:  2010-04-07       Impact factor: 6.875

Review 5.  Severe cutaneous adverse drug reactions.

Authors:  Wen-Hung Chung; Chuang-Wei Wang; Ro-Lan Dao
Journal:  J Dermatol       Date:  2016-05-06       Impact factor: 4.005

6.  Mycoplasma pneumoniae and atypical Stevens-Johnson syndrome: a case series.

Authors:  Karen A Ravin; Lara D Rappaport; Noel S Zuckerbraun; Robert M Wadowsky; Ellen R Wald; Marian M Michaels
Journal:  Pediatrics       Date:  2007-03-12       Impact factor: 7.124

7.  Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme.

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Review 8.  Toxic epidermal necrolysis and Stevens-Johnson syndrome.

Authors:  Thomas Harr; Lars E French
Journal:  Orphanet J Rare Dis       Date:  2010-12-16       Impact factor: 4.123

9.  Risk of serious skin disorders among users of oral antifungals: a population-based study.

Authors:  Jordi Castellsague; Luís-Alberto García-Rodríguez; Alberto Duque; Susana Pérez
Journal:  BMC Dermatol       Date:  2002-11-28

Review 10.  Severe Delayed Drug Reactions: Role of Genetics and Viral Infections.

Authors:  Rebecca Pavlos; Katie D White; Celestine Wanjalla; Simon A Mallal; Elizabeth J Phillips
Journal:  Immunol Allergy Clin North Am       Date:  2017-11       Impact factor: 3.479

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