Literature DB >> 2892784

Analysis of crossover type in the alpha -3.7 haplotype among sickle cell anemia patients from various parts of Africa.

C Dodé1, A Berth, J Rochette, R Girot, D Labie.   

Abstract

The frequency of alpha+-thalassemia has been determined in African populations carrying beta S-chromosomes of different origins. All these alpha+ thalassemias result from a right-ward deletion. Restriction mapping of the alpha -3.7/haplotype with the enzyme ApaI only showed the presence of a type I crossover. RsaI polymorphism at the 5' end of Z alpha 2 is largely represented in the normal population (gene frequency 23%) but, in our series, never associated with the alpha -3.7/haplotype.

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Mesh：

Year:  1988        PMID： 2892784     DOI： 10.1007/bf00278197

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  13 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Alpha-thalassemia haplotypes in the Algerian population.

Authors:  T Henni; F Morlé; B Lopez; P Colonna; J Godet
Journal:  Hum Genet       Date:  1987-03       Impact factor: 4.132

3.  Frequency and types of deletional alpha+-thalassemia in northern Sardinia.

Authors:  A Di Rienzo; L Felicetti; A Novelletto; G Forteleoni; B Colombo
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

4.  Analysis of the human alpha-globin gene cluster reveals a highly informative genetic locus.

Authors:  D R Higgs; J S Wainscoat; J Flint; A V Hill; S L Thein; R D Nicholls; H Teal; H Ayyub; T E Peto; A G Falusi
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

5.  alpha-Thalassemia among sickle cell anemia patients in various African populations.

Authors:  J Pagnier; O Dunda-Belkhodja; I Zohoun; J Teyssier; H Baya; G Jaeger; R L Nagel; D Labie
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

6.  Independent recombination events between the duplicated human alpha globin genes; implications for their concerted evolution.

Authors:  D R Higgs; A V Hill; D K Bowden; D J Weatherall; J B Clegg
Journal:  Nucleic Acids Res       Date:  1984-09-25       Impact factor: 16.971

7.  Boundaries of gene conversion within the duplicated human alpha-globin genes. Concerted evolution by segmental recombination.

Authors:  A M Michelson; S H Orkin
Journal:  J Biol Chem       Date:  1983-12-25       Impact factor: 5.157

8.  Triplicated alpha-globin loci in humans.

Authors:  M Goossens; A M Dozy; S H Embury; Z Zachariades; M G Hadjiminas; G Stamatoyannopoulos; Y W Kan
Journal:  Proc Natl Acad Sci U S A       Date:  1980-01       Impact factor: 11.205

9.  Evidence for the multicentric origin of the sickle cell hemoglobin gene in Africa.

Authors:  J Pagnier; J G Mears; O Dunda-Belkhodja; K E Schaefer-Rego; C Beldjord; R L Nagel; D Labie
Journal:  Proc Natl Acad Sci U S A       Date:  1984-03       Impact factor: 11.205

10.  Alpha-thalassemia is related to prolonged survival in sickle cell anemia.

Authors:  J G Mears; H M Lachman; D Labie; R L Nagel
Journal:  Blood       Date:  1983-08       Impact factor: 22.113
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