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Literature DB >> 2891136

Genetic linkage map of human chromosome 7 with 63 DNA markers.

D Barker¹, P Green, R Knowlton, J Schumm, E Lander, A Oliphant, H Willard, G Akots, V Brown, T Gravius.

Abstract

High-density genetic maps of individual human chromosomes will permit accurate localization of disease-associated genes and provide signposts that will be useful in the construction of physical maps. We have constructed a genetic map of chromosome 7 with 63 polymorphic DNA markers by using segregation data from 23 three-generation families and recently developed multilocus linkage-analysis techniques. The map spans 250 centimorgans in females and 170 centimorgans in males, with much of the difference being concentrated in a few intervals. The density and informativeness of the markers are such that there is a high probability of detecting linkage to any disease gene on this chromosome for which 20 phase-known meioses are available.

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Year: 1987 PMID： 2891136 PMCID： PMC299465 DOI： 10.1073/pnas.84.22.8006

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

29 in total

1. A new method for purifying lambda DNA from phage lysates.

Authors: C Helms; M Y Graham; J E Dutchik; M V Olson
Journal: DNA Date: 1985-02

2. A polymorphic DNA marker linked to cystic fibrosis is located on chromosome 7.

Authors: R G Knowlton; O Cohen-Haguenauer; N Van Cong; J Frézal; V A Brown; D Barker; J C Braman; J W Schumm; L C Tsui; M Buchwald
Journal: Nature Date: 1985 Nov 28-Dec 4 Impact factor: 49.962

3. Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location.

Authors: B Royer-Pokora; L M Kunkel; A P Monaco; S C Goff; P E Newburger; R L Baehner; F S Cole; J T Curnutte; S H Orkin
Journal: Nature Date: 1986 Jul 3-9 Impact factor: 49.962

4. Regional mapping of six cloned DNA sequences on human chromosome 7.

Authors: I Bartels; K H Grzeschik; D N Cooper; J Schmidtke
Journal: Am J Hum Genet Date: 1986-03 Impact factor: 11.025

5. The genetic linkage map of the human X chromosome.

Authors: D Drayna; R White
Journal: Science Date: 1985-11-15 Impact factor: 47.728

6. Molecular cloning of a new transforming gene from a chemically transformed human cell line.

Authors: C S Cooper; M Park; D G Blair; M A Tainsky; K Huebner; C M Croce; G F Vande Woude
Journal: Nature Date: 1984 Sep 6-11 Impact factor: 49.962

7. A closely linked genetic marker for cystic fibrosis.

Authors: R White; S Woodward; M Leppert; P O'Connell; M Hoff; J Herbst; J M Lalouel; M Dean; G Vande Woude
Journal: Nature Date: 1985 Nov 28-Dec 4 Impact factor: 49.962

8. Cystic fibrosis locus defined by a genetically linked polymorphic DNA marker.

Authors: L C Tsui; M Buchwald; D Barker; J C Braman; R Knowlton; J W Schumm; H Eiberg; J Mohr; D Kennedy; N Plavsic
Journal: Science Date: 1985-11-29 Impact factor: 47.728

9. A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16.

Authors: S T Reeders; M H Breuning; K E Davies; R D Nicholls; A P Jarman; D R Higgs; P L Pearson; D J Weatherall
Journal: Nature Date: 1985 Oct 10-16 Impact factor: 49.962

10. Detection of a frequent restriction fragment length polymorphism in the human T cell antigen receptor beta chain locus. A potential diagnostic tool.

Authors: N Berliner; A D Duby; C C Morton; P Leder; J G Seidman
Journal: J Clin Invest Date: 1985-09 Impact factor: 14.808

29 in total

1. Crossover in a Spanish cystic fibrosis family.

Authors: E Fernández; M Villamar; J Benítez
Journal: Hum Genet Date: 1990-11 Impact factor: 4.132

2. Multipoint analysis of human quantitative genetic variation.

Authors: D E Goldgar
Journal: Am J Hum Genet Date: 1990-12 Impact factor: 11.025

3. Statistical methods for multipoint radiation hybrid mapping.

Authors: M Boehnke; K Lange; D R Cox
Journal: Am J Hum Genet Date: 1991-12 Impact factor: 11.025

4. DNA sequence analysis of the KM19 locus linked to cystic fibrosis. Design of new oligonucleotides to remove non-specific PCR products.

Authors: R Anwar; K Murray; P J Hedge; J C Smith; A F Markham
Journal: Hum Genet Date: 1990-08 Impact factor: 4.132

5. Genetic linkage map of 46 DNA markers on human chromosome 16.

Authors: T P Keith; P Green; S T Reeders; V A Brown; P Phipps; A Bricker; K Falls; K S Rediker; J A Powers; C Hogan
Journal: Proc Natl Acad Sci U S A Date: 1990-08 Impact factor: 11.205

6. A clinically homogeneous group of families with facioscapulohumeral (Landouzy-Déjérine) muscular dystrophy: linkage analysis of six autosomes.

Authors: S J Jacobsen; E S Diala; B V Dorsey; M B Rising; R Graveline; K Falls; P Schultz; C Hogan; K Rediker; C D'Amico
Journal: Am J Hum Genet Date: 1990-09 Impact factor: 11.025

7. Identification and regional localization of DNA markers on chromosome 7 for the cloning of the cystic fibrosis gene.

Authors: J M Rommens; S Zengerling; J Burns; G Melmer; B S Kerem; N Plavsic; M Zsiga; D Kennedy; D Markiewicz; R Rozmahel
Journal: Am J Hum Genet Date: 1988-11 Impact factor: 11.025

Review 8. Human QTL linkage mapping.

Authors: Laura Almasy; John Blangero
Journal: Genetica Date: 2008-07-31 Impact factor: 1.082

9. Genetic mapping studies of 40 loci and 23 cosmids in chromosome 11p13-11q13, and exclusion of mu-calpain as the multiple endocrine neoplasia type 1 gene.

Authors: J T Pang; S E Lloyd; C Wooding; B Farren; B Pottinger; B Harding; S E Leigh; M A Pook; F J Benham; G T Gillett; R T Taggart; R V Thakker
Journal: Hum Genet Date: 1996-06 Impact factor: 4.132

10. Cloning human telomeric DNA fragments into Saccharomyces cerevisiae using a yeast-artificial-chromosome vector.

Authors: H C Riethman; R K Moyzis; J Meyne; D T Burke; M V Olson
Journal: Proc Natl Acad Sci U S A Date: 1989-08 Impact factor: 11.205