Literature DB >> 28893048

Effect of Sugar-Free and Regular Toothpaste on Salivary Glucose and pH among Type 2 Diabetes- A Randomized Crossover Trial.

Junaid Kapadia1, Arun Dodamani2, Priya Baviskar3, G N Karibasappa4, Parag Pathak5, Abhishek Bezalwar6.   

Abstract

INTRODUCTION: Diabetes is one of the most prevalent diseases of mankind having general as well as oral health manifestations. Also, there is an increase of salivary glucose level in diabetic, inducing saccharolytic bacteria in saliva which can have adverse effects on oral tissue. AIM: To assess and compare the effect of sugar-free toothpaste on salivary glucose and pH among Type 2 diabetic and non-diabetic individuals.
MATERIALS AND METHODS: A randomized controlled-crossover study was carried out on 30 Type 2 diabetic (Group A) and 45 non-diabetic (Group B) subjects. In first half of study, subjects in Group A and Group B were intervened with sugar-free and regular toothpaste respectively. Salivary glucose and pH was assessed before and after brushing at interval of one week for a period of four weeks. In second half, toothpastes were switched over between the groups, after sufficient washout period. Salivary glucose and pH were assessed again in the same manner for both the groups. The data was subjected to paired t-test and unpaired t-test for intragroup and intergroup comparison respectively.
RESULTS: Salivary glucose level was significantly reduced and salivary pH was increased significantly (p<0.001) in both groups with sugar free toothpaste when compared to regular toothpaste.
CONCLUSION: Sugar free toothpaste showed beneficial effect on salivary glucose level and salivary pH level on diabetes and non-diabetes population.

Entities:  

Keywords:  Brushing; Non-diabetics; Oral microbial flora; Vicco toothpaste

Year:  2017        PMID: 28893048      PMCID: PMC5583924          DOI: 10.7860/JCDR/2017/25580.10250

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  21 in total

1.  Salivary glucose concentrations in patients with diabetes mellitus--a minimally invasive technique for monitoring blood glucose levels.

Authors:  S Amer; M Yousuf; P Q Siddqiui; J Alam
Journal:  Pak J Pharm Sci       Date:  2001-01       Impact factor: 0.684

2.  Comparative study of the concentration of salivary and blood glucose in type 2 diabetic patients.

Authors:  Ana Carolina U Vasconcelos; Maria Sueli M Soares; Paulo C Almeida; Teresa C Soares
Journal:  J Oral Sci       Date:  2010-06       Impact factor: 1.556

3.  Estimation of salivary glucose, salivary amylase, salivary total protein and salivary flow rate in diabetics in India.

Authors:  Arati S Panchbhai; Shirish S Degwekar; Rahul R Bhowte
Journal:  J Oral Sci       Date:  2010-09       Impact factor: 1.556

4.  A comparison of triclosan and stannous fluoride toothpastes for inhibition of plaque regrowth. A crossover study designed to assess carry over.

Authors:  A Binney; M Addy; J Owens; J Faulkner
Journal:  J Clin Periodontol       Date:  1997-03       Impact factor: 8.728

Review 5.  Update on diabetes mellitus and related oral diseases.

Authors:  M Manfredi; M J McCullough; P Vescovi; Z M Al-Kaarawi; S R Porter
Journal:  Oral Dis       Date:  2004-07       Impact factor: 3.511

6.  Study of the buffering capacity, pH and salivary flow rate in type 2 well-controlled and poorly controlled diabetic patients.

Authors:  Maria José Bernardi; Alessandra Reis; Alessandro Dourado Loguercio; Ruth Kehrig; Mariana Ferreira Leite; José Nicolau
Journal:  Oral Health Prev Dent       Date:  2007       Impact factor: 1.256

Review 7.  An overview on antidiabetic medicinal plants having insulin mimetic property.

Authors:  D K Patel; S K Prasad; R Kumar; S Hemalatha
Journal:  Asian Pac J Trop Biomed       Date:  2012-04

8.  Salivary characteristics of diabetic children.

Authors:  María Elena López; María Eugenia Colloca; Rafael Gustavo Páez; Judit Nora Schallmach; Myriam Adriana Koss; Amalia Chervonagura
Journal:  Braz Dent J       Date:  2003-07-31

9.  Hypoglycemic effect of triphala on selected non insulin dependent Diabetes mellitus subjects.

Authors:  Sowmya S Rajan; Seema Antony
Journal:  Anc Sci Life       Date:  2008-01

10.  Salivary glucose concentration and excretion in normal and diabetic subjects.

Authors:  Cedric Jurysta; Nurdan Bulur; Berrin Oguzhan; Ilhan Satman; Temel M Yilmaz; Willy J Malaisse; Abdullah Sener
Journal:  J Biomed Biotechnol       Date:  2009-05-26
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