Literature DB >> 17366764

Study of the buffering capacity, pH and salivary flow rate in type 2 well-controlled and poorly controlled diabetic patients.

Maria José Bernardi1, Alessandra Reis, Alessandro Dourado Loguercio, Ruth Kehrig, Mariana Ferreira Leite, José Nicolau.   

Abstract

PURPOSE: This study measured the flow rate, pH and buffering capacity of saliva from well- and poorly metabolically controlled Type 2 diabetic patients in three cities of the southern part of Brazil, compared with healthy individuals from the same cities.
MATERIALS AND METHODS: Whole saliva was collected by mechanical stimulation and buffering capacity and glucose level were measured. Blood was collected after 12 hours fasting and glucose and glycosylated haemoglobin concentrations were determined. The data were analysed by one-way ANOVA and Student-Newman-Keuls (alpha= 0.05).
RESULTS: The flow rate was lower in the Type 2 diabetic patients, regardless of whether they were well or poorly metabolically controlled, compared with healthy individuals (p < 0.05). Salivary glucose concentration was higher in both diabetic patient groups, i.e. well and poorly metabolically controlled, than in the control (p < 0.05).
CONCLUSION: The metabolic control of hyperglycaemia was not sufficient to improve the salivary flow rate or the salivary glucose concentration.

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Year:  2007        PMID: 17366764

Source DB:  PubMed          Journal:  Oral Health Prev Dent        ISSN: 1602-1622            Impact factor:   1.256


  14 in total

1.  Salivary function impairment in type 2 Diabetes patients associated with concentration and genetic polymorphisms of chromogranin A.

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2.  Reduced salivary amylase activity in metabolic syndrome patients with obesity could be improved by treatment with a dipeptidyl peptidase IV inhibitor.

Authors:  Jitjiroj Ittichaicharoen; Arintaya Phrommintikul; Nipon Chattipakorn; Siriporn Chattipakorn
Journal:  Clin Oral Investig       Date:  2018-03-08       Impact factor: 3.573

3.  Comparison of salivary and serum glucose levels in diabetic patients.

Authors:  Shruti Gupta; Simarpreet Virk Sandhu; Himanta Bansal; Deepti Sharma
Journal:  J Diabetes Sci Technol       Date:  2014-10-07

Review 4.  The mechanism of protracted wound healing on oral mucosa in diabetes. Review.

Authors:  Yoshihiro Abiko; Denis Selimovic
Journal:  Bosn J Basic Med Sci       Date:  2010-08       Impact factor: 3.363

5.  Integrating genomic data from high-throughput studies with computational modeling reveals differences in the molecular basis of hyposalivation between type 1 and type 2 diabetes.

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Journal:  Clin Oral Investig       Date:  2017-03-03       Impact factor: 3.573

6.  Effect of Sugar-Free and Regular Toothpaste on Salivary Glucose and pH among Type 2 Diabetes- A Randomized Crossover Trial.

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Review 7.  Effect of diabetes mellitus type 2 on salivary glucose--a systematic review and meta-analysis of observational studies.

Authors:  Paulo Mascarenhas; Bruno Fatela; Isabel Barahona
Journal:  PLoS One       Date:  2014-07-15       Impact factor: 3.240

8.  Salivary alkaline phosphatase and calcium in caries-active type II diabetes mellitus patients: An in vivo study.

Authors:  Mithra N Hegde; Divya Tahiliani; Shilpa Shetty; Darshana Devadiga
Journal:  Contemp Clin Dent       Date:  2014-10

9.  Periodontal conditions, oral Candida albicans and salivary proteins in type 2 diabetic subjects with emphasis on gender.

Authors:  Fawad Javed; Lena Klingspor; Ulf Sundin; Mohammad Altamash; Björn Klinge; Per-Erik Engström
Journal:  BMC Oral Health       Date:  2009-05-12       Impact factor: 2.757

10.  Salivary gland dysfunction markers in type 2 diabetes mellitus patients.

Authors:  Juan Aitken-Saavedra; Gonzalo Rojas-Alcayaga; Andrea Maturana-Ramírez; Alejandro Escobar-Álvarez; Andrea Cortes-Coloma; Montserrat Reyes-Rojas; Valentina Viera-Sapiain; Claudia Villablanca-Martínez; Irene Morales-Bozo
Journal:  J Clin Exp Dent       Date:  2015-10-01
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