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Literature DB >> 2889183

A mouse homeobox containing gene on chromosome 11: sequence and tissue-specific expression.

F Meijlink¹, R de Laaf, P Verrijzer, O Destrée, V Kroezen, J Hilkens, J Deschamps.

Abstract

We have molecularly cloned a mouse homeobox containing gene by isolating cDNA and genomic clones. The gene is located in a previously described cluster on chromosome 11 (Hart et al. (1985) Cell 43, 9-18) and was identified as the Hox2.3 gene. We present the complete mRNA sequence of this gene and describe similarities to other homeobox containing genes, among which its human homologue, the cl gene. High expression of the Hox2.3 gene was found in kidney, testis, and spinal cord of adult mice, in the spinal cord of 12.5-17.5 day embryos and in differentiating EC cells depending on their treatment. Three different treatments of the pluripotent EC cell line P19, each leading to the induction of a specific differentiation pathway, resulted in all cases in induction of Hox2.3; however, major quantitative differences in this response were observed.

Entities: Gene Species

Mesh：

Substances：

Year: 1987 PMID： 2889183 PMCID： PMC306174 DOI： 10.1093/nar/15.17.6773

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

50 in total

1. Supercoil sequencing: a fast and simple method for sequencing plasmid DNA.

Authors: E Y Chen; P H Seeburg
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2. Human beta-nerve growth factor gene sequence highly homologous to that of mouse.

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3. Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins.

Authors: A Laughon; M P Scott
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4. The murine Hox-2 cluster of homeo box containing genes maps distal on chromosome 11 near the tail-short (Ts) locus.

Authors: M Münke; D R Cox; I J Jackson; B L Hogan; U Francke
Journal: Cytogenet Cell Genet Date: 1986

5. The homeo domain of a murine protein binds 5' to its own homeo box.

Authors: A Fainsod; L D Bogarad; T Ruusala; M Lubin; D M Crothers; F H Ruddle
Journal: Proc Natl Acad Sci U S A Date: 1986-12 Impact factor: 11.205

6. Expression of homologous homeo-box-containing genes in differentiated human teratocarcinoma cells and mouse embryos.

Authors: C A Hauser; A L Joyner; R D Klein; T K Learned; G R Martin; R Tjian
Journal: Cell Date: 1985-11 Impact factor: 41.582

7. Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1.

Authors: R Krumlauf; P W Holland; J H McVey; B L Hogan
Journal: Development Date: 1987-04 Impact factor: 6.868

8. Isolation of a mouse cDNA coding for a developmentally regulated, testis-specific transcript containing homeo box homology.

Authors: D J Wolgemuth; E Engelmyer; R N Duggal; E Gizang-Ginsberg; G L Mutter; C Ponzetto; C Viviano; Z F Zakeri
Journal: EMBO J Date: 1986-06 Impact factor: 11.598

9. Association of the H-Y male antigen with beta2-microglobulin on human lymphoid and differentiated mouse teratocarcinoma cell lines.

Authors: M Fellous; E Günther; R Kemler; J Wiels; R Berger; J L Guenet; H Jakob; F Jacob
Journal: J Exp Med Date: 1978-07-01 Impact factor: 14.307

10. Sequential expression of murine homeo box genes during F9 EC cell differentiation.

Authors: G Breier; M Bućan; U Francke; A M Colberg-Poley; P Gruss
Journal: EMBO J Date: 1986-09 Impact factor: 11.598

15 in total

1. A strategy for rapid production and screening of yeast artificial chromosome libraries.

Authors: W M Strauss; E Jaenisch; R Jaenisch
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

2. Primary structure, developmentally regulated expression and potential duplication of the zebrafish homeobox gene ZF-21.

Authors: P R Njølstad; A Molven; I Hordvik; J Apold; A Fjose
Journal: Nucleic Acids Res Date: 1988-10-11 Impact factor: 16.971

A mouse homeobox containing gene on chromosome 11: sequence and tissue-specific expression.

1. Supercoil sequencing: a fast and simple method for sequencing plasmid DNA.

2. Human beta-nerve growth factor gene sequence highly homologous to that of mouse.

3. Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins.

4. The murine Hox-2 cluster of homeo box containing genes maps distal on chromosome 11 near the tail-short (Ts) locus.

5. The homeo domain of a murine protein binds 5' to its own homeo box.

6. Expression of homologous homeo-box-containing genes in differentiated human teratocarcinoma cells and mouse embryos.

7. Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1.

8. Isolation of a mouse cDNA coding for a developmentally regulated, testis-specific transcript containing homeo box homology.

9. Association of the H-Y male antigen with beta2-microglobulin on human lymphoid and differentiated mouse teratocarcinoma cell lines.

10. Sequential expression of murine homeo box genes during F9 EC cell differentiation.

1. A strategy for rapid production and screening of yeast artificial chromosome libraries.

2. Primary structure, developmentally regulated expression and potential duplication of the zebrafish homeobox gene ZF-21.

3. Expression of Hox-2.4 homeobox gene directed by proviral insertion in a myeloid leukemia.

4. Stage- and tissue-specific expression of two homeo box genes in sea urchin embryos and adults.

5. Nucleotide sequence of the Hox2.3 gene region.

6. The murine Hox-2.4 promoter contains a functional octamer motif.

Review 7. Homeobox genes and male reproductive development.

8. Xenopus homeobox-containing cDNAs expressed in early development.

9. Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.

10. Structure and expression of Hox-2.2, a murine homeobox-containing gene.