Literature DB >> 28890680

Study of flow behaviors of droplet merging and splitting in microchannels using Micro-PIV measurement.

Feng Shen1, Yi Li1, Zhaomiao Liu1, XiuJun Li2,3.   

Abstract

Droplet merging and splitting are important droplet manipulations in droplet-based microfluidics. However, the fundamental flow behaviors of droplets were not systematically studied. Hence, we designed two different microstructures to achieve droplet merging and splitting respectively, and quantitatively compared different flow dynamics in different microstructures for droplet merging and splitting via micro-particle image velocimetry (micro-PIV) experiments. Some flow phenomena of droplets different from previous studies were observed during merging and splitting using a high-speed microscope. It was also found the obtained instantaneous velocity vector fields of droplets have significant influence on the droplets merging and splitting. For droplet merging, the probability of droplets coalescence (η) in a microgroove is higher (50% < η < 92%) than that in a T-junction microchannel (15% < η < 50%), and the highest coalescence efficiency (η = 92%) comes at the two-phase flow ratio e of 0.42 in the microgroove. Moreover, compared with a cylinder obstacle, Y-junction bifurcation can split droplets more effectively and the droplet flow during splitting is steadier. The results can provide better understanding of droplet behaviors and are useful for the design and applications of droplet-based microfluidics.

Entities:  

Keywords:  Droplet merging; Droplet splitting; Droplet-based microfluidics; Micro-particle image velocimetry (Micro-PIV); Velocity vector field

Year:  2017        PMID: 28890680      PMCID: PMC5589143          DOI: 10.1007/s10404-017-1902-y

Source DB:  PubMed          Journal:  Microfluid Nanofluidics        ISSN: 1613-4982            Impact factor:   2.529


  45 in total

1.  Geometrically mediated breakup of drops in microfluidic devices.

Authors:  D R Link; S L Anna; D A Weitz; H A Stone
Journal:  Phys Rev Lett       Date:  2004-02-06       Impact factor: 9.161

2.  High-throughput injection with microfluidics using picoinjectors.

Authors:  Adam R Abate; Tony Hung; Pascaline Mary; Jeremy J Agresti; David A Weitz
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-20       Impact factor: 11.205

Review 3.  Active droplet generation in microfluidics.

Authors:  Zhuang Zhi Chong; Say Hwa Tan; Alfonso M Gañán-Calvo; Shu Beng Tor; Ngiap Hiang Loh; Nam-Trung Nguyen
Journal:  Lab Chip       Date:  2016-01-07       Impact factor: 6.799

4.  Stability of a jet in confined pressure-driven biphasic flows at low Reynolds number in various geometries.

Authors:  Pierre Guillot; Annie Colin; Armand Ajdari
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2008-07-17

5.  Electrically initiated upstream coalescence cascade of droplets in a microfluidic flow.

Authors:  Michele Zagnoni; Charles N Baroud; Jonathan M Cooper
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2009-10-02

Review 6.  Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications.

Authors:  Daniel Mark; Stefan Haeberle; Günter Roth; Felix von Stetten; Roland Zengerle
Journal:  Chem Soc Rev       Date:  2010-01-25       Impact factor: 54.564

Review 7.  Microfluidics for manipulating cells.

Authors:  Xuan Mu; Wenfu Zheng; Jiashu Sun; Wei Zhang; Xingyu Jiang
Journal:  Small       Date:  2012-08-30       Impact factor: 13.281

8.  Microfluidic on-demand droplet merging using surface acoustic waves.

Authors:  Muhsincan Sesen; Tuncay Alan; Adrian Neild
Journal:  Lab Chip       Date:  2014-09-07       Impact factor: 6.799

9.  Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane).

Authors:  D C Duffy; J C McDonald; O J Schueller; G M Whitesides
Journal:  Anal Chem       Date:  1998-12-01       Impact factor: 6.986

10.  Microfluidic systems for single DNA dynamics.

Authors:  Danielle J Mai; Christopher Brockman; Charles M Schroeder
Journal:  Soft Matter       Date:  2012-07-03       Impact factor: 3.679

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  4 in total

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Journal:  Sens Actuators B Chem       Date:  2019-12-02       Impact factor: 7.460

Review 2.  Aptamer-functionalized metal-organic frameworks (MOFs) for biosensing.

Authors:  Mengzhen Lv; Wan Zhou; Hamed Tavakoli; Cynthia Bautista; Jianfei Xia; Zonghua Wang; XiuJun Li
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Journal:  Lab Chip       Date:  2021-07-13       Impact factor: 7.517

4.  Droplet Coalescence by Selective Wettability Enhancement in Microfluidic Devices.

Authors:  Nahla Alamoodi; Anas Alazzam
Journal:  Nanomaterials (Basel)       Date:  2020-04-12       Impact factor: 5.076

  4 in total

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