Literature DB >> 28841416

High-Definition Medicine.

Ali Torkamani1, Kristian G Andersen2, Steven R Steinhubl3, Eric J Topol3.   

Abstract

The foundation for a new era of data-driven medicine has been set by recent technological advances that enable the assessment and management of human health at an unprecedented level of resolution-what we refer to as high-definition medicine. Our ability to assess human health in high definition is enabled, in part, by advances in DNA sequencing, physiological and environmental monitoring, advanced imaging, and behavioral tracking. Our ability to understand and act upon these observations at equally high precision is driven by advances in genome editing, cellular reprogramming, tissue engineering, and information technologies, especially artificial intelligence. In this review, we will examine the core disciplines that enable high-definition medicine and project how these technologies will alter the future of medicine.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 28841416      PMCID: PMC5714316          DOI: 10.1016/j.cell.2017.08.007

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  118 in total

1.  Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial.

Authors:  Francis K L Chan; K F To; Justin C Y Wu; M Y Yung; W K Leung; Timothy Kwok; Y Hui; Henry L Y Chan; Cynthia S Y Chan; Elsie Hui; Jean Woo; Joseph J Y Sung
Journal:  Lancet       Date:  2002-01-05       Impact factor: 79.321

Review 2.  Normal oral, rectal, tympanic and axillary body temperature in adult men and women: a systematic literature review.

Authors:  Märtha Sund-Levander; Christina Forsberg; Lis Karin Wahren
Journal:  Scand J Caring Sci       Date:  2002-06

3.  First-trimester or second-trimester screening, or both, for Down's syndrome.

Authors:  Fergal D Malone; Jacob A Canick; Robert H Ball; David A Nyberg; Christine H Comstock; Radek Bukowski; Richard L Berkowitz; Susan J Gross; Lorraine Dugoff; Sabrina D Craigo; Ilan E Timor-Tritsch; Stephen R Carr; Honor M Wolfe; Kimberly Dukes; Diana W Bianchi; Alicja R Rudnicka; Allan K Hackshaw; Geralyn Lambert-Messerlian; Nicholas J Wald; Mary E D'Alton
Journal:  N Engl J Med       Date:  2005-11-10       Impact factor: 91.245

4.  MGMT gene silencing and benefit from temozolomide in glioblastoma.

Authors:  Monika E Hegi; Annie-Claire Diserens; Thierry Gorlia; Marie-France Hamou; Nicolas de Tribolet; Michael Weller; Johan M Kros; Johannes A Hainfellner; Warren Mason; Luigi Mariani; Jacoline E C Bromberg; Peter Hau; René O Mirimanoff; J Gregory Cairncross; Robert C Janzer; Roger Stupp
Journal:  N Engl J Med       Date:  2005-03-10       Impact factor: 91.245

5.  Development of autoantibodies before the clinical onset of systemic lupus erythematosus.

Authors:  Melissa R Arbuckle; Micah T McClain; Mark V Rubertone; R Hal Scofield; Gregory J Dennis; Judith A James; John B Harley
Journal:  N Engl J Med       Date:  2003-10-16       Impact factor: 91.245

6.  Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies.

Authors:  Sarah Lewington; Robert Clarke; Nawab Qizilbash; Richard Peto; Rory Collins
Journal:  Lancet       Date:  2002-12-14       Impact factor: 79.321

7.  The evolution of disability in Parkinson disease.

Authors:  Lisa M Shulman; Ann L Gruber-Baldini; Karen E Anderson; Christopher G Vaughan; Stephen G Reich; Paul S Fishman; William J Weiner
Journal:  Mov Disord       Date:  2008-04-30       Impact factor: 10.338

8.  Years of life lost due to obesity.

Authors:  Kevin R Fontaine; David T Redden; Chenxi Wang; Andrew O Westfall; David B Allison
Journal:  JAMA       Date:  2003-01-08       Impact factor: 56.272

9.  Can family history be used as a tool for public health and preventive medicine?

Authors:  Paula W Yoon; Maren T Scheuner; Kris L Peterson-Oehlke; Marta Gwinn; Andrew Faucett; Muin J Khoury
Journal:  Genet Med       Date:  2002 Jul-Aug       Impact factor: 8.822

10.  Human disease classification in the postgenomic era: a complex systems approach to human pathobiology.

Authors:  Joseph Loscalzo; Isaac Kohane; Albert-Laszlo Barabasi
Journal:  Mol Syst Biol       Date:  2007-07-10       Impact factor: 11.429

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  59 in total

Review 1.  An Individualized, Data-Driven Digital Approach for Precision Behavior Change.

Authors:  Shannon Wongvibulsin; Seth S Martin; Suchi Saria; Scott L Zeger; Susan A Murphy
Journal:  Am J Lifestyle Med       Date:  2019-04-25

Review 2.  Artificial Intelligence Transforms the Future of Health Care.

Authors:  Nariman Noorbakhsh-Sabet; Ramin Zand; Yanfei Zhang; Vida Abedi
Journal:  Am J Med       Date:  2019-01-31       Impact factor: 4.965

3.  Performance Status in Cancer: Not Broken, But Time for an Upgrade?

Authors:  Jessica M Scott; Guro Stene; Elisabeth Edvardsen; Lee W Jones
Journal:  J Clin Oncol       Date:  2020-06-25       Impact factor: 44.544

4.  New omic and network paradigms for deep understanding of therapeutic mechanisms for Fangji of traditional Chinese medicine.

Authors:  Dayue Darrel Duan; Zhong Wang; Yong-Yan Wang
Journal:  Acta Pharmacol Sin       Date:  2018-06       Impact factor: 6.150

Review 5.  [Rational use of genetic tests in internal medicine : Possibilities and limitations of next generation sequencing diagnostics].

Authors:  M Elbracht; R Meyer; T Eggermann; I Kurth
Journal:  Internist (Berl)       Date:  2018-08       Impact factor: 0.743

6.  The "Virtual Digital Twins" Concept in Precision Nutrition.

Authors:  Kalliopi Gkouskou; Ioannis Vlastos; Petros Karkalousos; Dimitrios Chaniotis; Despina Sanoudou; Aristides G Eliopoulos
Journal:  Adv Nutr       Date:  2020-11-16       Impact factor: 8.701

7.  A Proteomic Variant Approach (ProVarA) for Personalized Medicine of Inherited and Somatic Disease.

Authors:  Darren M Hutt; Salvatore Loguercio; Alexandre Rosa Campos; William E Balch
Journal:  J Mol Biol       Date:  2018-06-18       Impact factor: 5.469

Review 8.  Toward Electrophysiology-Based Intelligent Adaptive Deep Brain Stimulation for Movement Disorders.

Authors:  Andrea A Kühn; R Mark Richardson; Wolf-Julian Neumann; Robert S Turner; Benjamin Blankertz; Tom Mitchell
Journal:  Neurotherapeutics       Date:  2019-01       Impact factor: 7.620

9.  Visible Machine Learning for Biomedicine.

Authors:  Michael K Yu; Jianzhu Ma; Jasmin Fisher; Jason F Kreisberg; Benjamin J Raphael; Trey Ideker
Journal:  Cell       Date:  2018-06-14       Impact factor: 41.582

Review 10.  The Cholinergic System as a Treatment Target for Opioid Use Disorder.

Authors:  Kevin P Jensen; Elise E DeVito; Sarah Yip; Kathleen M Carroll; Mehmet Sofuoglu
Journal:  CNS Drugs       Date:  2018-11       Impact factor: 5.749

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