Literature DB >> 28831689

Balancing the Need for Personalization of QT Correction and Generalization of Study Results: Going Beyond Thorough QT Studies.

Igor Diemberger1, Emanuel Raschi2, Gianluca Trifirò3.   

Abstract

Mesh：

Year:  2017        PMID： 28831689     DOI： 10.1007/s40261-017-0563-7

Source DB:  PubMed          Journal:  Clin Drug Investig        ISSN： 1173-2563            Impact factor:   2.859


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  29 in total

1.  The thorough QT study - do we need more of the same?

Authors:  Yoon K Loke
Journal:  Br J Clin Pharmacol       Date:  2016-02-17       Impact factor: 4.335

2.  Replacing the thorough QT study: reflections of a baby in the bath water.

Authors:  Robert B Kleiman; Rashmi R Shah; Joel Morganroth
Journal:  Br J Clin Pharmacol       Date:  2014-08       Impact factor: 4.335

3.  Modulators of normal electrocardiographic intervals identified in a large electronic medical record.

Authors:  Andrea H Ramirez; Jonathan S Schildcrout; Dana L Blakemore; Dan R Masys; Jill M Pulley; Melissa A Basford; Dan M Roden; Joshua C Denny
Journal:  Heart Rhythm       Date:  2010-10-29       Impact factor: 6.343

4.  Relation between QT and RR intervals is highly individual among healthy subjects: implications for heart rate correction of the QT interval.

Authors:  M Malik; P Färbom; V Batchvarov; K Hnatkova; A J Camm
Journal:  Heart       Date:  2002-03       Impact factor: 5.994

Review 5.  Evolution of strategies to improve preclinical cardiac safety testing.

Authors:  Gary Gintant; Philip T Sager; Norman Stockbridge
Journal:  Nat Rev Drug Discov       Date:  2016-02-19       Impact factor: 84.694

6.  A Randomized Trial to Assess the Effect of Doravirine on the QTc Interval Using a Single Supratherapeutic Dose in Healthy Adult Volunteers.

Authors:  Sauzanne G Khalilieh; Ka Lai Yee; Li Fan; Rachael Liu; Walter Heber; Elise Dunzo; Ilias Triantafyllou; Azra Hussaini; Marian Iwamoto
Journal:  Clin Drug Investig       Date:  2017-10       Impact factor: 2.859

Review 7.  The effects of gender on electrical therapies for the heart: physiology, epidemiology, and access to therapies.

Authors:  Giuseppe Boriani; Stefano Lorenzetti; Elisabetta Cerbai; Giuseppe Oreto; Gabriele Bronzetti; Vincenzo Livio Malavasi; Alessandro Biffi; Luigi Padeletti; Gianluca Botto; Igor Diemberger
Journal:  Europace       Date:  2017-09-01       Impact factor: 5.214

8.  Assessment of the sensitivity of detecting drug-induced QTc changes using subject-specific rate correction.

Authors:  Raymundo Cassani González; Elien B Engels; Bruno Dubé; Réginald Nadeau; Alain Vinet; A Robert LeBlanc; Marcio Sturmer; Giuliano Becker; Teresa Kus; Vincent Jacquemet
Journal:  J Electrocardiol       Date:  2012-09-07       Impact factor: 1.438

Review 9.  Potential of non-antiarrhythmic drugs to provide an innovative upstream approach to the pharmacological prevention of sudden cardiac death.

Authors:  Giuseppe Boriani; Cinzia Valzania; Igor Diemberger; Mauro Biffi; Cristian Martignani; Matteo Bertini; Matteo Ziacchi; Giulia Domenichini; Davide Saporito; Claudio Rapezzi; Angelo Branzi
Journal:  Expert Opin Investig Drugs       Date:  2007-05       Impact factor: 6.206

10.  QTc changes after meal intake: sex differences and correlates.

Authors:  Katerina Hnatkova; Donna Kowalski; James J Keirns; E Marcel van Gelderen; Marek Malik
Journal:  J Electrocardiol       Date:  2014-08-02       Impact factor: 1.438
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  2 in total

1.  GWAS of the electrocardiographic QT interval in Hispanics/Latinos generalizes previously identified loci and identifies population-specific signals.

Authors:  Raúl Méndez-Giráldez; Stephanie M Gogarten; Jennifer E Below; Jie Yao; Amanda A Seyerle; Heather M Highland; Charles Kooperberg; Elsayed Z Soliman; Jerome I Rotter; Kathleen F Kerr; Kelli K Ryckman; Kent D Taylor; Lauren E Petty; Sanjiv J Shah; Matthew P Conomos; Nona Sotoodehnia; Susan Cheng; Susan R Heckbert; Tamar Sofer; Xiuqing Guo; Eric A Whitsel; Henry J Lin; Craig L Hanis; Cathy C Laurie; Christy L Avery
Journal:  Sci Rep       Date:  2017-12-06       Impact factor: 4.379

Review 2.  The Complex Management of Atrial Fibrillation and Cancer in the COVID-19 Era: Drug Interactions, Thromboembolic Risk, and Proarrhythmia.

Authors:  Milo Gatti; Emanuel Raschi; Elisabetta Poluzzi; Cristian Martignani; Stefania Salvagni; Andrea Ardizzoni; Igor Diemberger
Journal:  Curr Heart Fail Rep       Date:  2020-12
  2 in total

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