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Literature DB >> 28778681

On the Origin of lncRNAs: Missing Link Found.

Abstract

Non-coding (nc)RNAs known as enhancer-derived RNAs (eRNAs) and as long ncRNAs (lncRNAs) have received much attention, but their true functional specialization and evolutionary origins remain obscure. The recent characterization of Bloodlinc, an eRNA derived from a super-enhancer that also functions as a lncRNA, suggests that lncRNAs can evolve from eRNAs.

Entities: Chemical Gene Species

Keywords: CTCF; chromatin loop; eRNA; lncRNA; noncoding RNA; superenhancer; topological activation domain

Mesh：

Substances：
RNA, Long Noncoding

Year: 2017 PMID： 28778681 PMCID： PMC5610073 DOI： 10.1016/j.tig.2017.07.005

Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639

10 in total

1. Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation.

Authors: Juan R Alvarez-Dominguez; Wenqian Hu; Bingbing Yuan; Jiahai Shi; Staphany S Park; Austin A Gromatzky; Alexander van Oudenaarden; Harvey F Lodish
Journal: Blood Date: 2013-11-07 Impact factor: 22.113

Review 2. The noncoding RNA revolution-trashing old rules to forge new ones.

Authors: Thomas R Cech; Joan A Steitz
Journal: Cell Date: 2014-03-27 Impact factor: 41.582

3. Revisiting lncRNAs: How Do You Know Yours Is Not an eRNA?

Authors: Joaquín M Espinosa
Journal: Mol Cell Date: 2016-04-07 Impact factor: 17.970

4. In Vivo Characterization of Linc-p21 Reveals Functional cis-Regulatory DNA Elements.

Authors: Abigail F Groff; Diana B Sanchez-Gomez; Marcela M L Soruco; Chiara Gerhardinger; A Rasim Barutcu; Eric Li; Lara Elcavage; Olivia Plana; Lluvia V Sanchez; James C Lee; Martin Sauvageau; John L Rinn
Journal: Cell Rep Date: 2016-08-11 Impact factor: 9.423

5. Local regulation of gene expression by lncRNA promoters, transcription and splicing.

Authors: Jesse M Engreitz; Jenna E Haines; Elizabeth M Perez; Glen Munson; Jenny Chen; Michael Kane; Patrick E McDonel; Mitchell Guttman; Eric S Lander
Journal: Nature Date: 2016-10-26 Impact factor: 49.962

6. Master transcription factors and mediator establish super-enhancers at key cell identity genes.

Authors: Warren A Whyte; David A Orlando; Denes Hnisz; Brian J Abraham; Charles Y Lin; Michael H Kagey; Peter B Rahl; Tong Ihn Lee; Richard A Young
Journal: Cell Date: 2013-04-11 Impact factor: 41.582

7. Unlinking an lncRNA from Its Associated cis Element.

Authors: Vikram R Paralkar; Cristian C Taborda; Peng Huang; Yu Yao; Andrew V Kossenkov; Rishi Prasad; Jing Luan; James O J Davies; Jim R Hughes; Ross C Hardison; Gerd A Blobel; Mitchell J Weiss
Journal: Mol Cell Date: 2016-03-31 Impact factor: 17.970

8. The Super-Enhancer-Derived alncRNA-EC7/Bloodlinc Potentiates Red Blood Cell Development in trans.

Authors: Juan R Alvarez-Dominguez; Marko Knoll; Austin A Gromatzky; Harvey F Lodish
Journal: Cell Rep Date: 2017-06-20 Impact factor: 9.995

9. Enhancers compete with a long non-coding RNA for regulation of the Kcnq1 domain.

Authors: Bryant M Schultz; Gwendolyn A Gallicio; Matteo Cesaroni; Lena N Lupey; Nora Engel
Journal: Nucleic Acids Res Date: 2014-12-24 Impact factor: 16.971

Review 10. Minor Loops in Major Folds: Enhancer-Promoter Looping, Chromatin Restructuring, and Their Association with Transcriptional Regulation and Disease.

Authors: Navneet Matharu; Nadav Ahituv
Journal: PLoS Genet Date: 2015-12-03 Impact factor: 5.917

10 in total

14 in total

1. Enhancer RNAs in cancer: regulation, mechanisms and therapeutic potential.

Authors: Joo-Hyung Lee; Feng Xiong; Wenbo Li
Journal: RNA Biol Date: 2020-01-19 Impact factor: 4.652

Review 2. Enhancer RNAs are an important regulatory layer of the epigenome.

Authors: Vittorio Sartorelli; Shannon M Lauberth
Journal: Nat Struct Mol Biol Date: 2020-06-08 Impact factor: 15.369

3. Noncoding RNA Ginir functions as an oncogene by associating with centrosomal proteins.

Authors: Suchismita Panda; Meenakshi Setia; Navjot Kaur; Varsha Shepal; Vivek Arora; Divya Kumari Singh; Abir Mondal; Abhishek Teli; Madhura Tathode; Rajendra Gajula; L C Padhy; Anjali Shiras
Journal: PLoS Biol Date: 2018-10-08 Impact factor: 8.029

4. Dissecting super-enhancer hierarchy based on chromatin interactions.

Authors: Jialiang Huang; Kailong Li; Wenqing Cai; Xin Liu; Yuannyu Zhang; Stuart H Orkin; Jian Xu; Guo-Cheng Yuan
Journal: Nat Commun Date: 2018-03-05 Impact factor: 14.919

5. A family of long intergenic non-coding RNA genes in human chromosomal region 22q11.2 carry a DNA translocation breakpoint/AT-rich sequence.

Authors: Nicholas Delihas
Journal: PLoS One Date: 2018-04-18 Impact factor: 3.240

6. A novel long non-coding RNA, AC012456.4, as a valuable and independent prognostic biomarker of survival in oral squamous cell carcinoma.

Authors: Xuegang Hu; Zailing Qiu; Jianchai Zeng; Tingting Xiao; Zhihong Ke; Hongbing Lyu
Journal: PeerJ Date: 2018-08-13 Impact factor: 2.984

7. Urothelial carcinoma associated 1 promotes trophoblast invasion by regulating MMP9.

Authors: Hongfang Shao; Feng Jin; Jiangshan Hu; Zhangying Zhu; Fuju Tian; Minfang Tao; Yincheng Teng
Journal: Cell Biosci Date: 2019-09-23 Impact factor: 7.133

8. Prognostic significance of LncRNA GHET1 expression in various cancers: a systematic review and meta-analysis.

Authors: Jing Ye; Haiyan Sun; Zhengquan Feng; Qiqin Zhang; Yongliang Xia; Yunxi Ji; Qiqing Zhang
Journal: Biosci Rep Date: 2019-10-30 Impact factor: 3.840

9. Formation of a Family of Long Intergenic Noncoding RNA Genes with an Embedded Translocation Breakpoint Motif in Human Chromosomal Low Copy Repeats of 22q11.2-Some Surprises and Questions.

Authors: Nicholas Delihas
Journal: Noncoding RNA Date: 2018-07-20

10. Transcriptional control by enhancers and enhancer RNAs.

Authors: Michael W Lewis; Shen Li; Hector L Franco
Journal: Transcription Date: 2019-12-02