Literature DB >> 28770270

[R1 resection in rectal cancer].

H-R Raab1.   

Abstract

R1 resections in rectal cancer particularly affect the circumferential resection margin (CRM) and lead to increased local recurrence rates, more distant metastases and a poorer prognosis. The proximity of the tumor to the CRM is already sufficient to increases these risks; therefore, according to the guidelines, it is now necessary to distinguish between R0 wide (≥1 mm distance), R0 close (<1 mm) and R1. The surgical technique is decisive for avoiding R1 situations. The preparation follows the boundary layers and envelope fascia in a standardized radical way and if necessary deviates away from these structures and the tumor under en bloc resection of neighboring structures. Neoadjuvant therapy also contributes to the reduction of R1 situations but cannot compensate for inadequate surgical procedures.

Entities:  

Keywords:  Circumferential resection margin; Neoadjuvant therapy; R0 close; R0 wide; Surgical technique

Mesh:

Year:  2017        PMID: 28770270     DOI: 10.1007/s00104-017-0480-6

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  19 in total

1.  The Need for Consensus and Transparency in Assessing Population-Based Rates of Positive Circumferential Radial Margins in Rectal Cancer: Data from Consecutive Cases in a Large Region of Ontario, Canada.

Authors:  Christine Keng; Angela Coates; Vanja Grubac; Peter Lovrics; Franco DeNardi; Lehana Thabane; Marko Simunovic
Journal:  Ann Surg Oncol       Date:  2016-02       Impact factor: 5.344

Review 2.  Pelvic MRI for guiding treatment decisions in rectal cancer.

Authors:  Robert Glynne-Jones; David Tan; Vicky Goh
Journal:  Oncology (Williston Park)       Date:  2014-08       Impact factor: 2.990

3.  Structured pathology reporting improves the macroscopic assessment of rectal tumour resection specimens.

Authors:  Simon King; Margaret Dimech; Susan Johnstone
Journal:  Pathology       Date:  2016-04-21       Impact factor: 5.306

4.  Prognostic significance of circumferential margin involvement in rectal adenocarcinoma treated with preoperative chemoradiotherapy and low anterior resection.

Authors:  Pedro Luna-Pérez; Efraín Bustos-Cholico; Isabel Alvarado; Antonio Maffuz; Saúl Rodríguez-Ramírez; Marcos Gutiérrez de la Barrera; Sonia Labastida
Journal:  J Surg Oncol       Date:  2005-04-01       Impact factor: 3.454

5.  Continuous Effect of Radial Resection Margin on Recurrence and Survival in Rectal Cancer Patients Who Receive Preoperative Chemoradiation and Curative Surgery: A Multicenter Retrospective Analysis.

Authors:  SooYoon Sung; Sung Hwan Kim; Joo Hwan Lee; Taek Keun Nam; Songmi Jeong; Hong Seok Jang; Jin Ho Song; Jeong Won Lee; Jung Min Bae; Jong Hoon Lee
Journal:  Int J Radiat Oncol Biol Phys       Date:  2017-03-14       Impact factor: 7.038

6.  R1 rectal resection: look up and don't look down.

Authors:  Camille Tilly; Jérémie H Lefèvre; Magali Svrcek; Conor Shields; Jean-Francois Fléjou; Emmanuel Tiret; Yann Parc
Journal:  Ann Surg       Date:  2014-11       Impact factor: 12.969

7.  Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.

Authors:  Rolf Sauer; Torsten Liersch; Susanne Merkel; Rainer Fietkau; Werner Hohenberger; Clemens Hess; Heinz Becker; Hans-Rudolf Raab; Marie-Therese Villanueva; Helmut Witzigmann; Christian Wittekind; Tim Beissbarth; Claus Rödel
Journal:  J Clin Oncol       Date:  2012-04-23       Impact factor: 44.544

8.  The Will Rogers phenomenon. Stage migration and new diagnostic techniques as a source of misleading statistics for survival in cancer.

Authors:  A R Feinstein; D M Sosin; C K Wells
Journal:  N Engl J Med       Date:  1985-06-20       Impact factor: 91.245

9.  [R1 resection in the region of the lower gastrointestinal tract: relevance and therapeutic consequences].

Authors:  M Hünerbein; P M Schlag
Journal:  Chirurg       Date:  2007-09       Impact factor: 0.955

10.  Diagnostic Accuracy of MRI for Assessment of T Category and Circumferential Resection Margin Involvement in Patients With Rectal Cancer: A Meta-Analysis.

Authors:  Ge Zhang; Yu-Zhe Cai; Guo-Hui Xu
Journal:  Dis Colon Rectum       Date:  2016-08       Impact factor: 4.585

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  1 in total

Review 1.  Are Colon and Rectal Cancer Two Different Tumor Entities? A Proposal to Abandon the Term Colorectal Cancer.

Authors:  Stephan Paschke; Sakhavat Jafarov; Ludger Staib; Ernst-Dietrich Kreuser; Catharina Maulbecker-Armstrong; Marc Roitman; Torbjörn Holm; Curtis C Harris; Karl-Heinrich Link; Marko Kornmann
Journal:  Int J Mol Sci       Date:  2018-08-30       Impact factor: 5.923

  1 in total

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