Literature DB >> 28761495

Development and Validation of a HPLC-UV Method for the Evaluation of Ellagic Acid in Liquid Extracts of Eugenia uniflora L. (Myrtaceae) Leaves and Its Ultrasound-Assisted Extraction Optimization.

Paulo Isaac Dias Assunção1, Edemilson Cardoso da Conceição2, Leonardo Luiz Borges1, Joelma Abadia Marciano de Paula1.   

Abstract

A simple HPLC-UV method has been developed and validated for the quantification of ellagic acid (EA) in ethanol extracts of Eugenia uniflora L. (Myrtaceae) leaves. The ultrasound-assisted extraction (UAE) optimization was performed using a Box Behnken design (33) combined with response surface methodology to study the effects of the ethanol concentration (%, w/w), extraction time (minutes), and temperature (°C) on the EA concentration. The optimized results showed that the highest extraction yield of EA by UAE was 26.0 μg mL-1 when using 44% (w/w) ethanol as the solvent, 22 minutes as the extraction time, and 59°C as the extraction temperature. The concentration of EA in relation to the predicted value was 93.7%  ±  0.4. UAE showed a strong potential for EA extraction.

Entities:  

Year:  2017        PMID： 28761495      PMCID： PMC5518513          DOI： 10.1155/2017/1501038

Source DB:  PubMed          Journal:  Evid Based Complement Alternat Med        ISSN： 1741-427X            Impact factor:   2.629


  29 in total

1.  Improving effects of the extracts from Eugenia uniflora on hyperglycemia and hypertriglyceridemia in mice.

Authors:  I Arai; S Amagaya; Y Komatsu; M Okada; T Hayashi; M Kasai; M Arisawa; Y Momose
Journal:  J Ethnopharmacol       Date:  1999-12-15       Impact factor: 4.360

2.  Screening of plants used in south Brazilian folk medicine.

Authors:  C B Alice; V M Vargas; G A Silva; N C de Siqueira; E E Schapoval; J Gleye; J A Henriques; A T Henriques
Journal:  J Ethnopharmacol       Date:  1991-12       Impact factor: 4.360

3.  Isolation by pressurised fluid extraction (PFE) and identification using CPC and HPLC/ESI/MS of phenolic compounds from Brazilian cherry seeds (Eugenia uniflora L.).

Authors:  Alessandra L Oliveira; Emilie Destandau; Laëtitia Fougère; Michel Lafosse
Journal:  Food Chem       Date:  2013-08-29       Impact factor: 7.514

4.  In vitro anti-proliferative activities of ellagic acid.

Authors:  Jack N Losso; Rishipal R Bansode; Alfred Trappey; Hiba A Bawadi; Robert Truax
Journal:  J Nutr Biochem       Date:  2004-11       Impact factor: 6.048

5.  EBV DNA polymerase inhibition of tannins from Eugenia uniflora.

Authors:  M H Lee; J F Chiou; K Y Yen; L L Yang
Journal:  Cancer Lett       Date:  2000-06-30       Impact factor: 8.679

6.  Strong antioxidant activity of ellagic acid in mammalian cells in vitro revealed by the comet assay.

Authors:  F Festa; T Aglitti; G Duranti; R Ricordy; P Perticone; R Cozzi
Journal:  Anticancer Res       Date:  2001 Nov-Dec       Impact factor: 2.480

7.  Ultrasound-assisted extraction of azadirachtin from dried entire fruits of Azadirachta indica A. Juss. (Meliaceae) and its determination by a validated HPLC-PDA method.

Authors:  Joelma Abadia Marciano de Paula; Lucas Ferreira Brito; Karen Lorena Ferreira Neves Caetano; Mariana Cristina de Morais Rodrigues; Leonardo Luiz Borges; Edemilson Cardoso da Conceição
Journal:  Talanta       Date:  2015-11-03       Impact factor: 6.057

8.  Optimization of ultrasound assisted extraction of antioxidant compounds from marjoram (Origanum majorana L.) using response surface methodology.

Authors:  Mohammad B Hossain; Nigel P Brunton; Ankit Patras; Brijesh Tiwari; C P O'Donnell; Ana B Martin-Diana; Catherine Barry-Ryan
Journal:  Ultrason Sonochem       Date:  2011-11-23       Impact factor: 7.491

9.  Acid hydrolysis of crude tannins from infructescence of Platycarya strobilacea Sieb. et Zucc to produce ellagic acid.

Authors:  Liangliang Zhang; Yongmei Wang; Man Xu
Journal:  Nat Prod Res       Date:  2014-06-09       Impact factor: 2.861

10.  Simultaneous Determination of Gallic Acid, Ellagic Acid, and Eugenol in Syzygium aromaticum and Verification of Chemical Antagonistic Effect by the Combination with Curcuma aromatica Using Regression Analysis.

Authors:  Jung-Hoon Kim; Chang-Seob Seo; Seong-Sil Kim; Hyekyung Ha
Journal:  J Anal Methods Chem       Date:  2013-06-25       Impact factor: 2.193
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  3 in total

1.  Microwave-Assisted Improved Extraction and Purification of Anticancer Nimbolide from Azadirachta indica (Neem) Leaves.

Authors:  Panawan Suttiarporn; Vachira Choommongkol
Journal:  Molecules       Date:  2020-06-24       Impact factor: 4.411

2.  Gallic Acid as a Non-Selective Inhibitor of α/β-Hydrolase Fold Enzymes Involved in the Inflammatory Process: The Two Sides of the Same Coin.

Authors:  Marcos Hikari Toyama; Airam Rogero; Laila Lucyane Ferreira de Moraes; Gustavo Antônio Fernandes; Caroline Ramos da Cruz Costa; Mariana Novo Belchor; Agatha Manzi De Carli; Marcos Antônio de Oliveira
Journal:  Pharmaceutics       Date:  2022-02-06       Impact factor: 6.321

3.  Polyester-releasing sesamin by electrospinning technique for the application of bone tissue engineering.

Authors:  Vachira Choommongkol; Jetsada Ruangsuriya; Panawan Suttiarporn; Winita Punyodom; Boontharika Thapsukhon
Journal:  Des Monomers Polym       Date:  2022-08-12       Impact factor: 3.718
  3 in total

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