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Literature DB >> 28757069

Structural Foundations of RNA Silencing by Argonaute.

Jessica Sheu-Gruttadauria¹, Ian J MacRae².

Abstract

Nearly every cell in the human body contains a set of programmable gene-silencing proteins named Argonaute. Argonaute proteins mediate gene regulation by small RNAs and thereby contribute to cellular homeostasis during diverse physiological process, such as stem cell maintenance, fertilization, and heart development. Over the last decade, remarkable progress has been made toward understanding Argonaute proteins, small RNAs, and their roles in eukaryotic biology. Here, we review current understanding of Argonaute proteins from a structural prospective and discuss unanswered questions surrounding this fascinating class of enzymes.

Entities: CellLine Chemical Disease Gene Species

Keywords: Argonaute; RNA silencing; RNA-induced silencing complex; microRNA

Mesh：

Substances：
Argonaute Proteins

Year: 2017 PMID： 28757069 PMCID： PMC5576611 DOI： 10.1016/j.jmb.2017.07.018

Source DB: PubMed Journal: J Mol Biol ISSN： 0022-2836 Impact factor: 5.469

243 in total

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Authors: Ana Eulalio; Isabelle Behm-Ansmant; Daniel Schweizer; Elisa Izaurralde
Journal: Mol Cell Biol Date: 2007-04-02 Impact factor: 4.272

2. Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.

Authors: Gang Sheng; Hongtu Zhao; Jiuyu Wang; Yu Rao; Wenwen Tian; Daan C Swarts; John van der Oost; Dinshaw J Patel; Yanli Wang
Journal: Proc Natl Acad Sci U S A Date: 2013-12-27 Impact factor: 11.205

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Journal: RNA Date: 2006-06-14 Impact factor: 4.942

4. Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers.

Authors: Alireza Heravi-Moussavi; Michael S Anglesio; S-W Grace Cheng; Janine Senz; Winnie Yang; Leah Prentice; Anthony P Fejes; Christine Chow; Alicia Tone; Steve E Kalloger; Nancy Hamel; Andrew Roth; Gavin Ha; Adrian N C Wan; Sarah Maines-Bandiera; Clara Salamanca; Barbara Pasini; Blaise A Clarke; Anna F Lee; Cheng-Han Lee; Chengquan Zhao; Robert H Young; Samuel A Aparicio; Poul H B Sorensen; Michelle M M Woo; Niki Boyd; Steven J M Jones; Martin Hirst; Marco A Marra; Blake Gilks; Sohrab P Shah; William D Foulkes; Gregg B Morin; David G Huntsman
Journal: N Engl J Med Date: 2011-12-21 Impact factor: 91.245

5. Structural features of Argonaute-GW182 protein interactions.

Authors: Janina Pfaff; Janosch Hennig; Franz Herzog; Ruedi Aebersold; Michael Sattler; Dierk Niessing; Gunter Meister
Journal: Proc Natl Acad Sci U S A Date: 2013-09-16 Impact factor: 11.205

6. An endogenous small interfering RNA pathway in Drosophila.

Authors: Benjamin Czech; Colin D Malone; Rui Zhou; Alexander Stark; Catherine Schlingeheyde; Monica Dus; Norbert Perrimon; Manolis Kellis; James A Wohlschlegel; Ravi Sachidanandam; Gregory J Hannon; Julius Brennecke
Journal: Nature Date: 2008-05-07 Impact factor: 49.962

7. Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.

Authors: Aleksandra Helwak; Grzegorz Kudla; Tatiana Dudnakova; David Tollervey
Journal: Cell Date: 2013-04-25 Impact factor: 41.582

8. Degradation of cellular mir-27 by a novel, highly abundant viral transcript is important for efficient virus replication in vivo.

Authors: Lisa Marcinowski; Mélanie Tanguy; Astrid Krmpotic; Bernd Rädle; Vanda J Lisnić; Lee Tuddenham; Béatrice Chane-Woon-Ming; Zsolt Ruzsics; Florian Erhard; Corinna Benkartek; Marina Babic; Ralf Zimmer; Joanne Trgovcich; Ulrich H Koszinowski; Stipan Jonjic; Sébastien Pfeffer; Lars Dölken
Journal: PLoS Pathog Date: 2012-02-09 Impact factor: 6.823

9. piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis.

Authors: Wee Siong Sho Goh; Ilaria Falciatori; Oliver H Tam; Ralph Burgess; Oliver Meikar; Noora Kotaja; Molly Hammell; Gregory J Hannon
Journal: Genes Dev Date: 2015-05-15 Impact factor: 11.361

10. Structure of yeast Argonaute with guide RNA.

Authors: Kotaro Nakanishi; David E Weinberg; David P Bartel; Dinshaw J Patel
Journal: Nature Date: 2012-06-20 Impact factor: 49.962

41 in total

1. mRNA structural dynamics shape Argonaute-target interactions.

Authors: Suzan Ruijtenberg; Stijn Sonneveld; Tao Ju Cui; Ive Logister; Dion de Steenwinkel; Yao Xiao; Ian J MacRae; Chirlmin Joo; Marvin E Tanenbaum
Journal: Nat Struct Mol Biol Date: 2020-07-13 Impact factor: 15.369

2. Label-Free Electrophoretic Mobility Shift Assay (EMSA) for Measuring Dissociation Constants of Protein-RNA Complexes.

Authors: Minguk Seo; Li Lei; Martin Egli
Journal: Curr Protoc Nucleic Acid Chem Date: 2018-11-21

Review 3. Mechanistic Insights into MicroRNA-Mediated Gene Silencing.

Authors: Thomas F Duchaine; Marc R Fabian
Journal: Cold Spring Harb Perspect Biol Date: 2019-03-01 Impact factor: 10.005

Review 4. Double-Stranded RNA Sensors and Modulators in Innate Immunity.

Authors: Sun Hur
Journal: Annu Rev Immunol Date: 2019-01-23 Impact factor: 28.527

5. Regulation of MicroRNAs.

Authors: Kemal Ergin; Rahmi Çetinkaya
Journal: Methods Mol Biol Date: 2022

6. Short prokaryotic Argonautes provide defence against incoming mobile genetic elements through NAD⁺ depletion.

Authors: Mindaugas Zaremba; Donata Dakineviciene; Edvardas Golovinas; Evelina Zagorskaitė; Edvinas Stankunas; Anna Lopatina; Rotem Sorek; Elena Manakova; Audrone Ruksenaite; Arunas Silanskas; Simonas Asmontas; Algirdas Grybauskas; Ugne Tylenyte; Edvinas Jurgelaitis; Rokas Grigaitis; Kęstutis Timinskas; Česlovas Venclovas; Virginijus Siksnys
Journal: Nat Microbiol Date: 2022-10-03 Impact factor: 30.964