Literature DB >> 28747755

Hacking DNA copy number for circuit engineering.

Feilun Wu1, Lingchong You1,2.   

Abstract

DNA copy number represents an essential parameter in the dynamics of synthetic gene circuits but typically is not explicitly considered. A new study demonstrates how dynamic control of DNA copy number can serve as an effective strategy to program robust oscillations in gene expression circuits.

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Year:  2017        PMID： 28747755     DOI： 10.1038/ng.3923

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  14 in total

Review 1.  Copy-number control of the Escherichia coli chromosome: a plasmidologist's view.

Authors:  Kurt Nordström; Santanu Dasgupta
Journal:  EMBO Rep       Date:  2006-05       Impact factor: 8.807

Review 2.  Physiological heterogeneity in biofilms.

Authors:  Philip S Stewart; Michael J Franklin
Journal:  Nat Rev Microbiol       Date:  2008-03       Impact factor: 60.633

3.  Elements of biological oscillations in time and space.

Authors:  Yangxiaolu Cao; Allison Lopatkin; Lingchong You
Journal:  Nat Struct Mol Biol       Date:  2016-12-06       Impact factor: 15.369

4.  Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus.

Authors:  David Gresham; Renata Usaite; Susanne Manuela Germann; Michael Lisby; David Botstein; Birgitte Regenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-11       Impact factor: 11.205

5.  Chromosomal Arrangement of Phosphorelay Genes Couples Sporulation and DNA Replication.

Authors:  Jatin Narula; Anna Kuchina; Dong-Yeon D Lee; Masaya Fujita; Gürol M Süel; Oleg A Igoshin
Journal:  Cell       Date:  2015-07-09       Impact factor: 41.582

6.  Large-scale copy number polymorphism in the human genome.

Authors:  Jonathan Sebat; B Lakshmi; Jennifer Troge; Joan Alexander; Janet Young; Pär Lundin; Susanne Månér; Hillary Massa; Megan Walker; Maoyen Chi; Nicholas Navin; Robert Lucito; John Healy; James Hicks; Kenny Ye; Andrew Reiner; T Conrad Gilliam; Barbara Trask; Nick Patterson; Anders Zetterberg; Michael Wigler
Journal:  Science       Date:  2004-07-23       Impact factor: 47.728

7.  Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples.

Authors:  Tal Korem; David Zeevi; Jotham Suez; Adina Weinberger; Tali Avnit-Sagi; Maya Pompan-Lotan; Elad Matot; Ghil Jona; Alon Harmelin; Nadav Cohen; Alexandra Sirota-Madi; Christoph A Thaiss; Meirav Pevsner-Fischer; Rotem Sorek; Ramnik Xavier; Eran Elinav; Eran Segal
Journal:  Science       Date:  2015-07-30       Impact factor: 47.728

Review 8.  Discovery of microbial natural products by activation of silent biosynthetic gene clusters.

Authors:  Peter J Rutledge; Gregory L Challis
Journal:  Nat Rev Microbiol       Date:  2015-06-29       Impact factor: 60.633

9.  Oscillations by minimal bacterial suicide circuits reveal hidden facets of host-circuit physiology.

Authors:  Philippe Marguet; Yu Tanouchi; Eric Spitz; Cameron Smith; Lingchong You
Journal:  PLoS One       Date:  2010-07-30       Impact factor: 3.240

10.  Antibiotic-induced replication stress triggers bacterial competence by increasing gene dosage near the origin.

Authors:  Jelle Slager; Morten Kjos; Laetitia Attaiech; Jan-Willem Veening
Journal:  Cell       Date:  2014-04-10       Impact factor: 41.582
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