Literature DB >> 28716647

Earwax: A clue to discover fluoroacetate intoxication in cattle.

Engy Shokry1, Fabrício Carrião Dos Santos2, Paulo Henrique Jorge da Cunha3, Maria Clorinda Soares Fioravanti3, Antônio Dionísio Feitosa Noronha Filho3, Naiara Zedes Pereira4, Nelson Roberto Antoniosi Filho4.   

Abstract

An innovative method was developed to detect fluoroacetate poisoning in cattle by headspace/gas chromatographic analysis of earwax samples of intoxicated cattle. Samples were collected from 2 groups of cattle subjected to induced fluoroacetate intoxication, each group receiving a different dose of acetamide (antidote). Monofluoroacetic acid was detected in samples of intoxicated cattle in concentrations inversely proportional to the dose of acetamide. Thus, earwax analysis represents a successful approach for detection and monitoring of fluoroacetate poisoning.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Bovine; Compound 1080; Earwax; Fluoroacetate poisoning; HS/GC-MS

Mesh：

Substances：

Year:  2017        PMID： 28716647     DOI： 10.1016/j.toxicon.2017.07.014

Source DB:  PubMed          Journal:  Toxicon        ISSN： 0041-0101            Impact factor:   3.033


  3 in total

1.  A cerumenolomic approach to bovine trypanosomosis diagnosis.

Authors:  João Marcos G Barbosa; Débora Ribeiro de Mendonça; Lurian C David; Taynara C E Silva; Danielly A Fortuna Lima; Anselmo E de Oliveira; Welber Daniel Zanetti Lopes; Maria Clorinda S Fioravanti; Paulo H Jorge da Cunha; Nelson R Antoniosi Filho
Journal:  Metabolomics       Date:  2022-06-23       Impact factor: 4.747

2.  Methylene blue and monosodium glutamate improve neurologic signs after fluoroacetate poisoning.

Authors:  Vanessa E DeLey Cox; Matthew A Hartog; Erin Pueblo; Michelle Racine; Laura Jennings; Justin Tressler; Wing Y Tuet; Samuel Stone; Samuel A Pierce; Lily Thompson; Aliyah Dukes; Heidi Hoard-Fruchey; Benjamin Wong; Bryan J McCranor
Journal:  Ann N Y Acad Sci       Date:  2020-04-14       Impact factor: 6.499

3.  Earwax metabolomics: An innovative pilot metabolic profiling study for assessing metabolic changes in ewes during periparturition period.

Authors:  Engy Shokry; Julião Pereira; Jair Gonzalez Marques Júnior; Paulo Henrique Jorge da Cunha; Antônio Dionísio Feitosa Noronha Filho; Jessica Alves da Silva; Maria Clorinda Soares Fioravanti; Anselmo Elcana de Oliveira; Nelson Roberto Antoniosi Filho
Journal:  PLoS One       Date:  2017-08-25       Impact factor: 3.240
  3 in total

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