Sang-Yong Eom1, Eun-Bi Cho2, Moo-Kyung Oh2, Sun-Seog Kweon3, Hae-Sung Nam4, Yong-Dae Kim1, Heon Kim5,6. 1. Department of Preventive Medicine and Medical Research Institute, College of Medicine, Chungbuk National University, 1 Chungdae-ro, Seowon-gu, Cheongju, 28644, Korea. 2. Gangwon Regional Cancer Center, Chuncheon, Korea. 3. Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, Korea. 4. Department of Preventive Medicine, College of Medicine, Chungnam National University, Daejeon, Korea. 5. Department of Preventive Medicine and Medical Research Institute, College of Medicine, Chungbuk National University, 1 Chungdae-ro, Seowon-gu, Cheongju, 28644, Korea. kimheon@cbu.ac.kr. 6. Chungbuk Regional Cancer Center, Cheongju, Korea. kimheon@cbu.ac.kr.
Abstract
PURPOSE: Portland cement contains carcinogens such as chromium and free silica, and hence, inhalation of cement dust can cause respiratory tract cancers. The purpose of this study was to determine whether living near a cement plant increases the risk of respiratory tract cancers. METHODS: The study population consisted of 341,793 people, all of whom lived in administrative districts within 3-km radius of ten cement plants in Korea. The respiratory tract cancer incidence data (International Classification of Diseases, ten revision code C00-C14 and C30-C34) for 2008-2012 were obtained from regional cancer registries. Standardized incidence ratios (SIRs) for each cancer site in the respiratory tract were calculated using an indirect standardization method. RESULTS: Compared with the general Korean population, the incidence of lung and bronchus cancer (C33-C34) was significantly higher in all subjects [SIR 1.15, 95% confidence interval (CI) 1.02-1.29] and especially in the men subjects (SIR 1.47, 95% CI 1.29-1.68) in our study population. In addition, the incidence of larynx cancer in men (SIR 1.64, 95% CI 0.97-2.59) and salivary gland cancer in women (SIR 3.03, 95% CI 0.98-7.07) living near cement plants was marginally increased. CONCLUSIONS: These results suggest that environmental exposure to Portland cement dust is a risk factor for respiratory tract cancers.
PURPOSE: Portland cement contains carcinogens such as chromium and free silica, and hence, inhalation of cement dust can cause respiratory tract cancers. The purpose of this study was to determine whether living near a cement plant increases the risk of respiratory tract cancers. METHODS: The study population consisted of 341,793 people, all of whom lived in administrative districts within 3-km radius of ten cement plants in Korea. The respiratory tract cancer incidence data (International Classification of Diseases, ten revision code C00-C14 and C30-C34) for 2008-2012 were obtained from regional cancer registries. Standardized incidence ratios (SIRs) for each cancer site in the respiratory tract were calculated using an indirect standardization method. RESULTS: Compared with the general Korean population, the incidence of lung and bronchus cancer (C33-C34) was significantly higher in all subjects [SIR 1.15, 95% confidence interval (CI) 1.02-1.29] and especially in the men subjects (SIR 1.47, 95% CI 1.29-1.68) in our study population. In addition, the incidence of larynx cancer in men (SIR 1.64, 95% CI 0.97-2.59) and salivary gland cancer in women (SIR 3.03, 95% CI 0.98-7.07) living near cement plants was marginally increased. CONCLUSIONS: These results suggest that environmental exposure to Portland cement dust is a risk factor for respiratory tract cancers.
Entities:
Keywords:
Cement; Environmental exposure; Respiratory tract cancer; Standardized incidence ratio
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