| Literature DB >> 28700736 |
Jordan B Strom1, Daniel B Kramer1, Yun Wang2, Changyu Shen1, Jason H Wasfy3, Bruce E Landon4, Elissa H Wilker1, Robert W Yeh1.
Abstract
Few studies have examined rates and causes of short-term readmissions among adults across age and insurance types. We compared rates, characteristics, and costs of 30-day readmission after all-cause hospitalizations across insurance types in the US. We retrospectively evaluated alive patients ≥18 years old, discharged for any cause, 1/1/13-11/31/13, 2006 non-federal hospitals in 21 states in the Nationwide Readmissions Database. The primary stratification variable of interest was primary insurance. Comorbid conditions were assessed based on Elixhauser comorbidities, as defined by administrative billing codes. Additional measures included diagnoses for index hospitalizations leading to rehospitalization. Hierarchical multivariable logistic regression models, with hospital site as a random effect, were used to calculate the adjusted odds of 30-day readmissions by age group and insurance categories. Cost and discharge estimates were weighted per NRD procedures to reflect a nationally representative sample. Diagnoses for index hospitalizations leading to rehospitalization were determined. Among 12,533,551 discharges, 1,818,093 (14.5%) resulted in readmission within 30 days. Medicaid insurance was associated with the highest adjusted odds ratio (AOR) for readmission both in those ≥65 years old (AOR 1.12, 95%CI 1.10-1.14; p <0.001), and 45-64 (AOR 1.67, 95% CI 1.66-1.69; p < 0.001), and Medicare in the 18-44 group (Medicare vs. private insurance: AOR 1.99, 95% CI 1.96-2.01; p <0.001). Discharges for psychiatric or substance abuse disorders, septicemia, and heart failure accounted for the largest numbers of readmissions, with readmission rates of 24.0%, 17.9%, 22.9% respectively. Total costs for readmissions were 50.7 billion USD, highest for Medicare (29.6 billion USD), with non-Medicare costs exceeding 21 billion USD. While Medicare readmissions account for more than half of the total burden of readmissions, costs of non-Medicare readmissions are nonetheless substantial. Medicaid patients have the highest odds of readmission in individuals older than age 44, commonly due to hospitalizations for psychiatric illness and substance abuse disorders. Medicaid patients represent a population at uniquely high risk for readmission.Entities:
Mesh:
Year: 2017 PMID: 28700736 PMCID: PMC5507267 DOI: 10.1371/journal.pone.0180767
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Baseline characteristics among readmitted and non-readmitted patients by age category.
| Total | Age | |||||||
|---|---|---|---|---|---|---|---|---|
| 18–44, y | 45–64, y | 65+, y | ||||||
| Variable Name | Readmitted (N = 1 818 093) | Not readmitted (N = 10 715 458) | Readmitted (N = 393 191) | Not Readmitted (N = 3 371 155) | Readmitted (N = 590 885) | Not readmitted (N = 3 067 274) | Readmitted (N = 834 017) | Not Readmitted (N = 4 227 029) |
| 60.4 (19.1) | 56.3 (20.8) | 32.2 (7.5) | 30.7 (7.2) | 55.2 (5.6) | 55.2 (5.6) | 79.0 (2.6) | 78.9 (2.6) | |
| 950666 (52.3) | 6504940 (60.7) | 233396 (59.4) | 2579990 (76.5) | 273178 (46.2) | 273178 (46.2) | 444092 (53.2) | 1481304 (35.0) | |
| 346486 (19.1) | 1203372 (11.2) | 14511 (3.7) | 41601 (1.2) | 88176 (14.9) | 275799 (9.0) | 243799 (29.2) | 885972 (21.0) | |
| 23206 (1.3) | 86383 (0.8) | 719 (0.2) | 2965 (0.1) | 5853 (1.0) | 21722 (0.7) | 16634 (2.0) | 61696 (1.5) | |
| 221583 (12.2) | 1159687 (10.8) | 17930 (4.6) | 119331 (3.5) | 57364 (9.7) | 295271 (9.6) | 146289 (17.5) | 745085 (17.6) | |
| 166046 (9.1) | 722003 (6.7) | 26406 (6.7) | 100732 (3.0) | 50779 (8.6) | 196512 (6.4) | 88861 (10.7) | 424759 (10.0) | |
| 77610 (4.3) | 342413 (3.2) | 4249 (1.1) | 19204 (0.6) | 14533 (2.5) | 61594 (2.0) | 58828 (7.1) | 261615 (6.2) | |
| 1001183 (55.1) | 5058609 (47.2) | 86431 (22.0) | 380769 (11.3) | 329103 (55.7) | 1649495 (53.8) | 585649 (70.2) | 3028345 (71.6) | |
| 28425 (1.6) | 136452 (1.3) | 632 (0.2) | 3171 (0.1) | 5802 (1.0) | 27731 (0.9) | 21991 (2.6) | 105550 (2.5) | |
| 116577 (6.4) | 458340 (4.3) | 15116 (3.8) | 81029 (2.4) | 44163 (7.5) | 149826 (4.9) | 57298 (6.9) | 227485 (5.4) | |
| 338792 (18.6) | 1122814 (10.5) | 25360 (6.4) | 56865 (1.7) | 94862 (16.1) | 268169 (8.7) | 218570 (26.2) | 797780 (18.9) | |
| 411640 (22.6) | 1787013 (16.7) | 46464 (11.8) | 254346 (7.5) | 136866 (23.2) | 570192 (18.6) | 228310 (27.4) | 962475 (22.8) | |
| 52631 (2.9) | 189166 (1.8) | 4545 (1.2) | 14014 (0.4) | 14310 (2.4) | 46704 (1.5) | 33776 (4.0) | 128448 (3.0) | |
| 13251 (0.7) | 61429 (0.6) | 33 (0.0) | 103 (0.0) | 1201 (0.2) | 4019 (0.1) | 12017 (1.4) | 57307 (1.4) | |
| 205963 (11.3) | 842286 (7.9) | 75367 (19.2) | 336385 (10.0) | 103197 (17.5) | 385645 (12.6) | 27399 (3.3) | 120256 (2.8) | |
| 145290 (8.0) | 571459 (5.3) | 3916 (1.0) | 12258 (0.4) | 36102 (6.1) | 130187 (4.2) | 105272 (12.6) | 429014 (10.1) | |
| 61676 (3.4) | 195902 (1.8) | 4806 (1.2) | 12327 (0.4) | 25220 (4.3) | 73063 (2.4) | 31650 (3.8) | 110512 (2.6) | |
| 361847 (19.9) | 3435596 (32.1) | 67578 (17.2) | 1078327 (32.0) | 123135 (20.8) | 1106734 (36.1) | 171134 (20.5) | 1250535 (29.6) | |
| 118733 (6.5) | 475282 (4.4) | 31012 (7.9) | 130252 (3.9) | 52953 (9.0) | 195538 (6.4) | 34768 (4.2) | 149492 (3.5) | |
| 85339 (4.7) | 300811 (2.8) | 13034 (3.3) | 51318 (1.5) | 48846 (8.3) | 164092 (5.3) | 23459 (2.8) | 85401 (2.0) | |
| 217345 (12.0) | 1067778 (10.0) | 41205 (10.5) | 206120 (6.1) | 83326 (14.1) | 400612 (13.1) | 92814 (11.1) | 461046 (10.9) | |
| 535823 (29.5) | 2320300 (21.7) | 45357 (11.5) | 179370 (5.3) | 190926 (32.3) | 814275 (26.5) | 299540 (35.9) | 1326655 (31.4) | |
| 22150 (1.2) | 72943 (0.7) | 1733 (0.4) | 5189 (0.2) | 6508 (1.1) | 20069 (0.7) | 13909 (1.7) | 47685 (1.1) | |
| 50860 (2.8) | 207446 (1.9) | 8605 (2.2) | 34240 (1.0) | 17590 (3.0) | 68934 (2.2) | 24665 (3.0) | 104272 (2.5) | |
| 123459 (6.8) | 422739 (3.9) | 13769 (3.5) | 43781 (1.3) | 39219 (6.6) | 120249 (3.9) | 70471 (8.4) | 258709 (6.1) | |
| 1739893 (95.7) | 9285190 (86.7) | 330369 (84.0) | 2061583 (61.2) | 580095 (98.2) | 2977234 (97.1) | 829429 (99.4) | 4246373 (100.0) | |
| 1346300 (74.1) | 6300096 (58.8) | 260212 (66.2) | 1358492 (40.3) | 441121 (74.7) | 1952554 (63.7) | 644967 (77.3) | 2989050 (70.7) | |
| 248737 (13.7) | 2715576 (25.3) | 60379 (15.4) | 1069400 (31.7) | 80905 (13.7) | 776147 (25.3) | 107453 (12.9) | 870029 (20.6) | |
| 1759254 (96.8) | 10259042 (95.7) | 379684 (96.6) | 3256070 (96.6) | 571339 (96.7) | 2920676 (95.2) | 808231 (96.9) | 4082296 (96.6) | |
| 1009941 (55.5) | 4758913 (44.4) | 58198 (14.8) | 185080 (5.5) | 189732 (32.1) | 710594 (23.2) | 762011 (91.4) | 3109170 (73.6) | |
| 312019 (17.2) | 1775009 (16.6) | 147526 (37.5) | 1172608 (34.8) | 149891 (25.4) | 537878 (17.5) | 14602 (1.8) | 57295 (1.4) | |
| 87464 (4.8) | 536813 (5.0) | 45216 (11.5) | 278943 (8.3) | 39736 (6.7) | 244394 (8.0) | 2512 (0.3) | 13476 (0.3) | |
| 332589 (18.3) | 3119955 (29.1) | 114103 (29.0) | 1515916 (45.0) | 173041 (29.3) | 1323934 (43.2) | 45445 (5.4) | 45445 (6.6) | |
| 76080 (4.2) | 524768 (4.9) | 28148 (7.2) | 218608 (6.4) | 38485 (6.5) | 250474 (8.1) | 9447 (1.1) | 1001543 (18.1) |
aAll p-values for comparisons are < 0.001 and two-tailed. Categorical variables are expressed as counts and percentages and continuous variables as means and standard deviations.
Abbreviations: y = years. SD = standard deviation.
Adjusted odds of 30-day readmission by age category and payer group.
| Age Group | |||
|---|---|---|---|
| Payer | 18–44 | 45–64 | 65+ |
| 1.39 (1.37–1.41) | 1.07 (1.06–1.08) | 0.96 (0.92–1.00) | |
| 1.52 (1.52–1.53) | 1.67 (1.66–1.69) | 1.12 (1.10–1.14) | |
| 1.99 (1.96–2.01) | 1.56 (1.55–1.57) | Ref | |
| Ref | Ref | 0.87 (0.86–0.88) |
aEffect estimates are expressed as adjusted odds ratios and 95% confidence intervals by age and payer category.
Covariates included in Table A in .
Most common discharge diagnoses for the index admission for patients readmitted within 30 days stratified by payer and rates of readmission.
| 1 | Schizophrenic Disorders | 295.xx | 14,574 | 25.67 | 1 | Heart Failure | 428.xx | 63,814 | 23.04 |
| 2 | Episodic Mood Disorders | 296.xx | 13,353 | 19.86 | 2 | Septicemia | 038.xx | 60,117 | 19.02 |
| 3 | Diabetes Mellitus | 250.xx | 11,964 | 22.74 | 3 | Chronic bronchitis | 491.xx | 36,916 | 20.64 |
| 4 | Septicemia | 038.xx | 10,498 | 20.57 | 4 | Cardiac dysrhythmias | 427.xx | 35,526 | 17.38 |
| 5 | Heart Failure | 428.xx | 9,368 | 28.64 | 5 | Pneumonia | 486.xx | 33,630 | 16.73 |
| 1 | Septicemia | 038.xx | 10,560 | 14.21 | 1 | Diabetes Mellitus | 250.xx | 3,967 | 17.04 |
| 2 | Cardiac dysrhythmias | 427.xx | 7,817 | 13.08 | 2 | Episodic Mood Disorders | 296.xx | 3,925 | 14.89 |
| 3 | Episodic Mood Disorders | 296.xx | 7,767 | 11.81 | 3 | Respiratory or Chest Symptoms | 786.xx | 3,634 | 21.44 |
| 4 | Respiratory or Chest Symptoms | 786.xx | 7,273 | 15.9 | 4 | Diseases of Pancreas | 577.xx | 2,510 | 16.08 |
| 5 | Diabetes Mellitus | 250.xx | 6,914 | 15.74 | 5 | Alcohol-induced Mental Disorder | 291.xx | 2,471 | 16.85 |