Hee Joon Kim1, Jong Seung Kim2,3. 1. Department of Radiology, Presbyterian Medical Center, Jeonju, Republic of Korea. 2. Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Chonbuk National University, Jeonju, Republic of Korea. 3. Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Republic of Korea.
Abstract
OBJECTIVES/HYPOTHESIS: Core needle biopsy is an effective diagnostic tool widely used in many oncological diagnostic approaches. It provides an adequate tissue sample for histological evaluation of architecture, which allows tumor grading and classification of malignant and benign tumors. This study aimed to provide an updated meta-analysis and systematic review of core needle biopsy in the salivary glands. STUDY DESIGN: A literature search using PubMed, Embase, and the Cochrane Library through December 2016. METHODS: Data on true positives, true negatives, false positives, and false negatives were extracted from the relevant articles. Methodological quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 tool. We calculated accuracy, sensitivity, and specificity with 95% confidence intervals (CIs) using random-effects models that considered both within- and between-study variations. RESULTS: Our search included 10 observational studies. For core needle biopsy, the sensitivity and specificity for the diagnosis of salivary glands were 0.94 (95% CI: 0.92-0.96, I2 = 18.7%, χ2 P = .27) and 0.98 (95% CI: 0.97-0.99, I2 = 79.6%, χ2 P = .00), respectively. The area under the summary receiver operating characteristic curve was 0.98 (95% CI: 0.97-0.99). Seven hematomas, one case of temporary facial paralysis caused by local anesthesia, and no tumor seeding were reported from a total of 1,315 procedures. CONCLUSIONS: Ultrasound core needle biopsy of salivary glands is an excellent diagnostic tool in terms of accuracy, technical performance, and safety profile. LEVEL OF EVIDENCE: NA. Laryngoscope, 128:118-125, 2018.
OBJECTIVES/HYPOTHESIS: Core needle biopsy is an effective diagnostic tool widely used in many oncological diagnostic approaches. It provides an adequate tissue sample for histological evaluation of architecture, which allows tumor grading and classification of malignant and benign tumors. This study aimed to provide an updated meta-analysis and systematic review of core needle biopsy in the salivary glands. STUDY DESIGN: A literature search using PubMed, Embase, and the Cochrane Library through December 2016. METHODS: Data on true positives, true negatives, false positives, and false negatives were extracted from the relevant articles. Methodological quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 tool. We calculated accuracy, sensitivity, and specificity with 95% confidence intervals (CIs) using random-effects models that considered both within- and between-study variations. RESULTS: Our search included 10 observational studies. For core needle biopsy, the sensitivity and specificity for the diagnosis of salivary glands were 0.94 (95% CI: 0.92-0.96, I2 = 18.7%, χ2 P = .27) and 0.98 (95% CI: 0.97-0.99, I2 = 79.6%, χ2 P = .00), respectively. The area under the summary receiver operating characteristic curve was 0.98 (95% CI: 0.97-0.99). Seven hematomas, one case of temporary facial paralysis caused by local anesthesia, and no tumor seeding were reported from a total of 1,315 procedures. CONCLUSIONS: Ultrasound core needle biopsy of salivary glands is an excellent diagnostic tool in terms of accuracy, technical performance, and safety profile. LEVEL OF EVIDENCE: NA. Laryngoscope, 128:118-125, 2018.
Authors: Katharine Julia Hurry; Dilhara Karunaratne; Suzanne Westley; Alessandra Booth; Keith C R B Ramesar; Ting Ting Zhang; Michael Williams; David C Howlett Journal: Br J Radiol Date: 2021-12-03 Impact factor: 3.039
Authors: Antonio Matrone; Luigi De Napoli; Liborio Torregrossa; Aleksandr Aghababyan; Piermarco Papini; Carlo Enrico Ambrosini; Rosa Cervelli; Clara Ugolini; Fulvio Basolo; Eleonora Molinaro; Rossella Elisei; Gabriele Materazzi Journal: Front Oncol Date: 2022-04-05 Impact factor: 5.738