Literature DB >> 28698706

Personhood status of the human zygote, embryo, fetus.

John Janez Miklavcic1, Paul Flaman2.   

Abstract

The fields of biology, medicine, and embryology have described the developmental milestones of humans throughout gestation in great detail. It is less clear as to when humans are recognized as people, persons, or beings with rights that are protected by legislation. The practice of law is irrevocably intertwined with that of ethical conduct; and the time at which a human life is considered a person has implications that extend to health care, legislation on abortion, and autonomy of individuals. This article reviews the economical position that fertilization is the moment that personhood of the conceptus begins. Alternate positions proposing that personhood begins at other possible times after fertilization are presented and contrasted to the economical hypothesis. Summary: This article is an original work critically analyzing the various arguments for human personhood at fertilization and thereafter. The various positions on human personhood are compared and contrasted herein. The time of the human lifespan at which personhood is conferred has important implications for health care, legislation, and personal autonomy.

Entities:  

Keywords:  Capacity; Embryo; Fertilization; Fetus; Personhood; Zygote

Year:  2017        PMID: 28698706      PMCID: PMC5499222          DOI: 10.1080/00243639.2017.1299896

Source DB:  PubMed          Journal:  Linacre Q        ISSN: 0024-3639


  19 in total

Review 1.  Rewiring the brain with cell transplantation in Parkinson's disease.

Authors:  Afsaneh Gaillard; Mohamed Jaber
Journal:  Trends Neurosci       Date:  2011-03       Impact factor: 13.837

2.  A defense of the whole-brain concept of death.

Authors:  J L Bernat
Journal:  Hastings Cent Rep       Date:  1998 Mar-Apr       Impact factor: 2.683

3.  Developmental potential of zona pellucida-free oocytes obtained following mild in vitro fertilization.

Authors:  Satoshi Ueno; Daniel Bodri; Kazuo Uchiyama; Tadashi Okimura; Takashi Okuno; Tamotsu Kobayashi; Keiichi Kato
Journal:  Fertil Steril       Date:  2014-09-23       Impact factor: 7.329

4.  Reprogramming within hours following nuclear transfer into mouse but not human zygotes.

Authors:  Dieter Egli; Alice E Chen; Genevieve Saphier; Justin Ichida; Claire Fitzgerald; Kathryn J Go; Nicole Acevedo; Jay Patel; Manfred Baetscher; William G Kearns; Robin Goland; Rudolph L Leibel; Douglas A Melton; Kevin Eggan
Journal:  Nat Commun       Date:  2011-10-04       Impact factor: 14.919

Review 5.  Systematic review of patient-reported outcome instruments for gastroesophageal reflux disease symptoms.

Authors:  Nimish B Vakil; Katarina Halling; Anja Becher; Anna Rydén
Journal:  Eur J Gastroenterol Hepatol       Date:  2013-01       Impact factor: 2.566

6.  Endometrial differentiation in the peri-implantation phase of women with recurrent miscarriage: a morphological and immunohistochemical study.

Authors:  E Serle; J D Aplin; T C Li; M A Warren; R A Graham; M W Seif; I D Cooke
Journal:  Fertil Steril       Date:  1994-11       Impact factor: 7.329

7.  Personhood and neuroscience: naturalizing or nihilating?

Authors:  Martha J Farah; Andrea S Heberlein
Journal:  Am J Bioeth       Date:  2007-01       Impact factor: 11.229

Review 8.  Cancer chemoprevention and nutriepigenetics: state of the art and future challenges.

Authors:  Clarissa Gerhauser
Journal:  Top Curr Chem       Date:  2013

9.  Identification of common variants associated with human hippocampal and intracranial volumes.

Authors:  Jason L Stein; Sarah E Medland; Alejandro Arias Vasquez; Derrek P Hibar; Rudy E Senstad; Anderson M Winkler; Roberto Toro; Katja Appel; Richard Bartecek; Ørjan Bergmann; Manon Bernard; Andrew A Brown; Dara M Cannon; M Mallar Chakravarty; Andrea Christoforou; Martin Domin; Oliver Grimm; Marisa Hollinshead; Avram J Holmes; Georg Homuth; Jouke-Jan Hottenga; Camilla Langan; Lorna M Lopez; Narelle K Hansell; Kristy S Hwang; Sungeun Kim; Gonzalo Laje; Phil H Lee; Xinmin Liu; Eva Loth; Anbarasu Lourdusamy; Morten Mattingsdal; Sebastian Mohnke; Susana Muñoz Maniega; Kwangsik Nho; Allison C Nugent; Carol O'Brien; Martina Papmeyer; Benno Pütz; Adaikalavan Ramasamy; Jerod Rasmussen; Mark Rijpkema; Shannon L Risacher; J Cooper Roddey; Emma J Rose; Mina Ryten; Li Shen; Emma Sprooten; Eric Strengman; Alexander Teumer; Daniah Trabzuni; Jessica Turner; Kristel van Eijk; Theo G M van Erp; Marie-Jose van Tol; Katharina Wittfeld; Christiane Wolf; Saskia Woudstra; Andre Aleman; Saud Alhusaini; Laura Almasy; Elisabeth B Binder; David G Brohawn; Rita M Cantor; Melanie A Carless; Aiden Corvin; Michael Czisch; Joanne E Curran; Gail Davies; Marcio A A de Almeida; Norman Delanty; Chantal Depondt; Ravi Duggirala; Thomas D Dyer; Susanne Erk; Jesen Fagerness; Peter T Fox; Nelson B Freimer; Michael Gill; Harald H H Göring; Donald J Hagler; David Hoehn; Florian Holsboer; Martine Hoogman; Norbert Hosten; Neda Jahanshad; Matthew P Johnson; Dalia Kasperaviciute; Jack W Kent; Peter Kochunov; Jack L Lancaster; Stephen M Lawrie; David C Liewald; René Mandl; Mar Matarin; Manuel Mattheisen; Eva Meisenzahl; Ingrid Melle; Eric K Moses; Thomas W Mühleisen; Matthias Nauck; Markus M Nöthen; Rene L Olvera; Massimo Pandolfo; G Bruce Pike; Ralf Puls; Ivar Reinvang; Miguel E Rentería; Marcella Rietschel; Joshua L Roffman; Natalie A Royle; Dan Rujescu; Jonathan Savitz; Hugo G Schnack; Knut Schnell; Nina Seiferth; Colin Smith; Vidar M Steen; Maria C Valdés Hernández; Martijn Van den Heuvel; Nic J van der Wee; Neeltje E M Van Haren; Joris A Veltman; Henry Völzke; Robert Walker; Lars T Westlye; Christopher D Whelan; Ingrid Agartz; Dorret I Boomsma; Gianpiero L Cavalleri; Anders M Dale; Srdjan Djurovic; Wayne C Drevets; Peter Hagoort; Jeremy Hall; Andreas Heinz; Clifford R Jack; Tatiana M Foroud; Stephanie Le Hellard; Fabio Macciardi; Grant W Montgomery; Jean Baptiste Poline; David J Porteous; Sanjay M Sisodiya; John M Starr; Jessika Sussmann; Arthur W Toga; Dick J Veltman; Henrik Walter; Michael W Weiner; Joshua C Bis; M Arfan Ikram; Albert V Smith; Vilmundur Gudnason; Christophe Tzourio; Meike W Vernooij; Lenore J Launer; Charles DeCarli; Sudha Seshadri; Ole A Andreassen; Liana G Apostolova; Mark E Bastin; John Blangero; Han G Brunner; Randy L Buckner; Sven Cichon; Giovanni Coppola; Greig I de Zubicaray; Ian J Deary; Gary Donohoe; Eco J C de Geus; Thomas Espeseth; Guillén Fernández; David C Glahn; Hans J Grabe; John Hardy; Hilleke E Hulshoff Pol; Mark Jenkinson; René S Kahn; Colm McDonald; Andrew M McIntosh; Francis J McMahon; Katie L McMahon; Andreas Meyer-Lindenberg; Derek W Morris; Bertram Müller-Myhsok; Thomas E Nichols; Roel A Ophoff; Tomas Paus; Zdenka Pausova; Brenda W Penninx; Steven G Potkin; Philipp G Sämann; Andrew J Saykin; Gunter Schumann; Jordan W Smoller; Joanna M Wardlaw; Michael E Weale; Nicholas G Martin; Barbara Franke; Margaret J Wright; Paul M Thompson
Journal:  Nat Genet       Date:  2012-04-15       Impact factor: 38.330

10.  The zinc spark is an inorganic signature of human egg activation.

Authors:  Francesca E Duncan; Emily L Que; Nan Zhang; Eve C Feinberg; Thomas V O'Halloran; Teresa K Woodruff
Journal:  Sci Rep       Date:  2016-04-26       Impact factor: 4.379

View more
  6 in total

1.  Will CRISPR Germline Engineering Close the Door to an Open Future?

Authors:  Rachel L Mintz; John D Loike; Ruth L Fischbach
Journal:  Sci Eng Ethics       Date:  2018-10-24       Impact factor: 3.525

2.  Discarding IVF embryos: reporting on global practices.

Authors:  M Simopoulou; K Sfakianoudis; P Giannelou; A Rapani; E Maziotis; P Tsioulou; S Grigoriadis; E Simopoulos; D Mantas; M Lambropoulou; M Koutsilieris; K Pantos; J C Harper
Journal:  J Assist Reprod Genet       Date:  2019-12-01       Impact factor: 3.412

Review 3.  CRISPR-Cas and Its Wide-Ranging Applications: From Human Genome Editing to Environmental Implications, Technical Limitations, Hazards and Bioethical Issues.

Authors:  Roberto Piergentili; Alessandro Del Rio; Fabrizio Signore; Federica Umani Ronchi; Enrico Marinelli; Simona Zaami
Journal:  Cells       Date:  2021-04-21       Impact factor: 7.666

Review 4.  CRISPR Ethics: Moral Considerations for Applications of a Powerful Tool.

Authors:  Carolyn Brokowski; Mazhar Adli
Journal:  J Mol Biol       Date:  2018-06-07       Impact factor: 6.151

Review 5.  Posthumous reproduction in Iranian law.

Authors:  Elaheh Mohseni; Mahmoud Abbasi
Journal:  Reprod Biomed Soc Online       Date:  2021-01-15

Review 6.  CRISPR/Cas9 system: a reliable and facile genome editing tool in modern biology.

Authors:  Darakhshan Javaid; Shahid Yousuf Ganie; Younis Ahmad Hajam; Mohd Salim Reshi
Journal:  Mol Biol Rep       Date:  2022-08-28       Impact factor: 2.742

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.