Literature DB >> 28695223

A Journey in Science: Cell-Cycle Control.

Paul Nurse1.   

Abstract

Real innovations in medicine and science are historic and singular; the stories behind each occurrence are precious. At Molecular Medicine we have established the Anthony Cerami Award in Translational Medicine to document and preserve these histories. The monographs recount the seminal events as told in the voice of the original investigators who provided the crucial early insight. These essays capture the essence of discovery, chronicling the birth of ideas that created new fields of research; and launched trajectories that persisted and ultimately influenced how disease is prevented, diagnosed, and treated. In this volume, the Cerami Award Monograph is by Paul Nurse, Director, The Francis Crick Institute in London, UK. A visionary in the field of cell biology, this is the story of Dr. Nurse's scientific journey.

Keywords:  Cancer invasion and metastasis; cell biology; cell death; endothelial cell; molecular biology

Mesh:

Substances:

Year:  2017        PMID: 28695223      PMCID: PMC5469718          DOI: 10.2119/molmed.2016.00189

Source DB:  PubMed          Journal:  Mol Med        ISSN: 1076-1551            Impact factor:   6.354


  29 in total

1.  Genetic control of cell size at cell division in yeast.

Authors:  P Nurse
Journal:  Nature       Date:  1975-08-14       Impact factor: 49.962

2.  Control of cell size at division in fission yeast by a growth-modulated size control over nuclear division.

Authors:  P Fantes; P Nurse
Journal:  Exp Cell Res       Date:  1977-07       Impact factor: 3.905

3.  Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog.

Authors:  P Russell; P Nurse
Journal:  Cell       Date:  1987-05-22       Impact factor: 41.582

4.  Genetic control of the cell division cycle in yeast. II. Genes controlling DNA replication and its initiation.

Authors:  L H Hartwell
Journal:  J Mol Biol       Date:  1971-07-14       Impact factor: 5.469

5.  Isolation of genes by complementation in yeast: molecular cloning of a cell-cycle gene.

Authors:  K A Nasmyth; S I Reed
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

6.  The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function.

Authors:  J Hayles; D Beach; B Durkacz; P Nurse
Journal:  Mol Gen Genet       Date:  1986-02

7.  Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2.

Authors:  M G Lee; P Nurse
Journal:  Nature       Date:  1987 May 7-13       Impact factor: 49.962

8.  Sequence of the cell division gene CDC2 from Schizosaccharomyces pombe; patterns of splicing and homology to protein kinases.

Authors:  J Hindley; G A Phear
Journal:  Gene       Date:  1984-11       Impact factor: 3.688

9.  Functionally homologous cell cycle control genes in budding and fission yeast.

Authors:  D Beach; B Durkacz; P Nurse
Journal:  Nature       Date:  1982-12-23       Impact factor: 49.962

10.  A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Authors:  Jacqueline Hayles; Valerie Wood; Linda Jeffery; Kwang-Lae Hoe; Dong-Uk Kim; Han-Oh Park; Silvia Salas-Pino; Christian Heichinger; Paul Nurse
Journal:  Open Biol       Date:  2013-05-22       Impact factor: 6.411

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  4 in total

Review 1.  How to turn an organism into a model organism in 10 'easy' steps.

Authors:  Benjamin J Matthews; Leslie B Vosshall
Journal:  J Exp Biol       Date:  2020-02-07       Impact factor: 3.312

Review 2.  Recent advances with cyclin-dependent kinase inhibitors: therapeutic agents for breast cancer and their role in immuno-oncology.

Authors:  Gabriele Di Sante; Jessica Pagé; Xuanmao Jiao; Omar Nawab; Massimo Cristofanilli; Emmanuel Skordalakes; Richard G Pestell
Journal:  Expert Rev Anticancer Ther       Date:  2019-06-20       Impact factor: 4.512

Review 3.  The palette of techniques for cell cycle analysis.

Authors:  Anna E Eastman; Shangqin Guo
Journal:  FEBS Lett       Date:  2020-05-22       Impact factor: 3.864

4.  Chemopreventive targeted treatment of head and neck precancer by Wee1 inhibition.

Authors:  Anne M van Harten; D Vicky de Boer; Sanne R Martens-de Kemp; Marijke Buijze; Sonja H Ganzevles; Keith D Hunter; C René Leemans; Victor W van Beusechem; Rob M F Wolthuis; Renée X de Menezes; Ruud H Brakenhoff
Journal:  Sci Rep       Date:  2020-02-11       Impact factor: 4.379

  4 in total

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