Heike Daldrup-Link1,2. 1. Department of Radiology, Lucile Packard Children's Hospital, and Pediatric Molecular Imaging Program (@PedsMIPS) in the Molecular Imaging Program at Stanford (MIPS), Stanford University. 2. Department of Pediatrics, Stanford University.
Abstract
PURPOSE: To review how PET/MR technology could add value for pediatric cancer patients. RECENT FINDINGS: Since many primary tumors in children are evaluated with MRI and metastases are detected with PET/CT, integrated PET/MR can be a time-efficient and convenient solution for pediatric cancer staging. 18F-FDG PET/MR can assess primary tumors and the whole body in one imaging session, avoid repetitive anesthesia and reduce radiation exposure compared to 18F-FDG PET/CT. This article lists 10 action points, which might improve the clinical value of PET/MR for children with cancer. However, even if PET/MR proves valuable, it cannot enter mainstream applications if it is not accessible to the majority of pediatric cancer patients. Therefore, innovations are needed to make PET/MR scanners affordable and increase patient throughput. SUMMARY: PET/MR offers opportunities for more efficient, accurate and safe diagnoses of pediatric cancer patients. The impact on patient management and outcomes has to be substantiated by large-scale prospective clinical trials.
PURPOSE: To review how PET/MR technology could add value for pediatric cancerpatients. RECENT FINDINGS: Since many primary tumors in children are evaluated with MRI and metastases are detected with PET/CT, integrated PET/MR can be a time-efficient and convenient solution for pediatric cancer staging. 18F-FDG PET/MR can assess primary tumors and the whole body in one imaging session, avoid repetitive anesthesia and reduce radiation exposure compared to 18F-FDG PET/CT. This article lists 10 action points, which might improve the clinical value of PET/MR for children with cancer. However, even if PET/MR proves valuable, it cannot enter mainstream applications if it is not accessible to the majority of pediatric cancerpatients. Therefore, innovations are needed to make PET/MR scanners affordable and increase patient throughput. SUMMARY: PET/MR offers opportunities for more efficient, accurate and safe diagnoses of pediatric cancerpatients. The impact on patient management and outcomes has to be substantiated by large-scale prospective clinical trials.
Authors: F A Hoffer; A Y Nikanorov; W E Reddick; S M Bodner; X Xiong; D Jones-Wallace; S A Gronemeyer; B N Rao; W M Kauffman; T Laor Journal: Pediatr Radiol Date: 2000-05
Authors: H E Daldrup-Link; C Franzius; T M Link; D Laukamp; J Sciuk; H Jürgens; O Schober; E J Rummeny Journal: AJR Am J Roentgenol Date: 2001-07 Impact factor: 3.959
Authors: Heike E Daldrup-Link; Ernst J Rummeny; Bettina Ihssen; Joachim Kienast; Thomas M Link Journal: Eur Radiol Date: 2002-02-05 Impact factor: 5.315
Authors: David J Brenner; Richard Doll; Dudley T Goodhead; Eric J Hall; Charles E Land; John B Little; Jay H Lubin; Dale L Preston; R Julian Preston; Jerome S Puskin; Elaine Ron; Rainer K Sachs; Jonathan M Samet; Richard B Setlow; Marco Zaider Journal: Proc Natl Acad Sci U S A Date: 2003-11-10 Impact factor: 11.205
Authors: F Montravers; D McNamara; J Landman-Parker; D Grahek; K Kerrou; N Younsi; M Wioland; G Leverger; J N Talbot Journal: Eur J Nucl Med Mol Imaging Date: 2002-06-25 Impact factor: 9.236
Authors: Anuj Pareek; Anne M Muehe; Ashok J Theruvath; Praveen K Gulaka; Sheri L Spunt; Heike E Daldrup-Link Journal: J Vis Exp Date: 2017-12-19 Impact factor: 1.355