Jaclyn A Stephens1,2, Cynthia F Salorio1,2, Anita D Barber3, Sarah R Risen4, Stewart H Mostofsky1,5,6, Stacy J Suskauer1,2,5. 1. a Kennedy Krieger Institute , Johns Hopkins School of Medicine , Baltimore , MD , USA. 2. b Department of Physical Medicine and Rehabilitation , Johns Hopkins School of Medicine , Baltimore , MD , USA. 3. c Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research , Manhasset, NY, USA. 4. d Department of Pediatric Neurology , Baylor College of Medicine , Texas Children's Hospital, Houston TX , USA. 5. e Department of Pediatrics , Johns Hopkins School of Medicine , Baltimore , MD , USA. 6. f Department of Neurology , Johns Hopkins School of Medicine , Baltimore , MD , USA.
Abstract
PURPOSE AND METHOD: This study examined functional connectivity of the default mode network (DMN) and examined brain-behavior relationships in a pilot cohort of children with chronic mild to moderate traumatic brain injury (TBI). RESULTS: Compared to uninjured peers, children with TBI demonstrated less anti-correlated functional connectivity between DMN and right Brodmann Area 40 (BA 40). In children with TBI, more anomalous less anti-correlated) connectivity between DMN and right BA 40 was linked to poorer performance on response inhibition tasks. CONCLUSION: Collectively, these preliminary findings suggest that functional connectivity between DMN and BA 40 may relate to longterm functional outcomes in chronic pediatric TBI.
PURPOSE AND METHOD: This study examined functional connectivity of the default mode network (DMN) and examined brain-behavior relationships in a pilot cohort of children with chronic mild to moderate traumatic brain injury (TBI). RESULTS: Compared to uninjured peers, children with TBI demonstrated less anti-correlated functional connectivity between DMN and right Brodmann Area 40 (BA 40). In children with TBI, more anomalous less anti-correlated) connectivity between DMN and right BA 40 was linked to poorer performance on response inhibition tasks. CONCLUSION: Collectively, these preliminary findings suggest that functional connectivity between DMN and BA 40 may relate to longterm functional outcomes in chronic pediatric TBI.
Authors: Nikolaus Kriegeskorte; Martin A Lindquist; Thomas E Nichols; Russell A Poldrack; Edward Vul Journal: J Cereb Blood Flow Metab Date: 2010-06-23 Impact factor: 6.200
Authors: Kristen E Robinson; Stephanie Fountain-Zaragoza; Maureen Dennis; H Gerry Taylor; Erin D Bigler; Kenneth Rubin; Kathryn Vannatta; Cynthia A Gerhardt; Terry Stancin; Keith Owen Yeates Journal: J Neurotrauma Date: 2014-09-24 Impact factor: 5.269
Authors: Kausar Abbas; Trey E Shenk; Victoria N Poole; Evan L Breedlove; Larry J Leverenz; Eric A Nauman; Thomas M Talavage; Meghan E Robinson Journal: Brain Connect Date: 2014-10-21
Authors: Cordell M Baker; Joshua D Burks; Robert G Briggs; Jordan Stafford; Andrew K Conner; Chad A Glenn; Goksel Sali; Tressie M McCoy; James D Battiste; Daniel L O'Donoghue; Michael E Sughrue Journal: Oper Neurosurg (Hagerstown) Date: 2018-12-01 Impact factor: 2.703
Authors: Cordell M Baker; Joshua D Burks; Robert G Briggs; Andrew K Conner; Chad A Glenn; Krishna Manohar; Camille K Milton; Goksel Sali; Tressie M McCoy; James D Battiste; Daniel L O'Donoghue; Michael E Sughrue Journal: Oper Neurosurg (Hagerstown) Date: 2018-12-01 Impact factor: 2.703
Authors: Emily L Dennis; Talin Babikian; Christopher C Giza; Paul M Thompson; Robert F Asarnow Journal: Neuroscientist Date: 2018-02-28 Impact factor: 7.519
Authors: Naomi S Sta Maria; Saman Sargolzaei; Mayumi L Prins; Emily L Dennis; Robert F Asarnow; David A Hovda; Neil G Harris; Christopher C Giza Journal: Exp Neurol Date: 2019-05-02 Impact factor: 5.620
Authors: David Gabrieli; Samantha N Schumm; Nicholas F Vigilante; Brandon Parvesse; David F Meaney Journal: PLoS One Date: 2020-09-23 Impact factor: 3.240
Authors: Emily L Dennis; Karen Caeyenberghs; Robert F Asarnow; Talin Babikian; Brenda Bartnik-Olson; Erin D Bigler; Anthony Figaji; Christopher C Giza; Naomi J Goodrich-Hunsaker; Cooper B Hodges; Kristen R Hoskinson; Marsh Königs; Harvey S Levin; Hannah M Lindsey; Abigail Livny; Jeffrey E Max; Tricia L Merkley; Mary R Newsome; Alexander Olsen; Nicholas P Ryan; Matthew S Spruiell; Stacy J Suskauer; Sophia I Thomopoulos; Ashley L Ware; Christopher G Watson; Anne L Wheeler; Keith Owen Yeates; Brandon A Zielinski; Paul M Thompson; David F Tate; Elisabeth A Wilde Journal: Brain Imaging Behav Date: 2021-04 Impact factor: 3.978