Baptiste Pignon1, Franck Schürhoff2, Andrei Szöke2, Pierre A Geoffroy3, Renaud Jardri4, Jean-Luc Roelandt5, Benjamin Rolland6, Pierre Thomas7, Guillaume Vaiva7, Ali Amad7. 1. CHRU de Lille, Pôle de psychiatrie, Hôpital Fontan, Lille 59000, France; AP-HP, DHU PePSY, Hôpitaux Universitaires Henri-Mondor, Pôle de Psychiatrie, Créteil 94000, France; INSERM, U955, team 15, Créteil 94000, France; Fondation FondaMental, Créteil 94000, France; UPEC, Université Paris-Est, Faculté de Médecine, Créteil 94000, France. Electronic address: baptistepignon@yahoo.fr. 2. AP-HP, DHU PePSY, Hôpitaux Universitaires Henri-Mondor, Pôle de Psychiatrie, Créteil 94000, France; INSERM, U955, team 15, Créteil 94000, France; Fondation FondaMental, Créteil 94000, France; UPEC, Université Paris-Est, Faculté de Médecine, Créteil 94000, France. 3. Inserm, U1144, Paris F-75006, France; Université Paris Descartes, UMR-S 1144, Paris F-75006, France; Université Paris Diderot, Sorbonne Paris Cité, UMR-S 1144, Paris F-75013, France; AP-HP, GH Saint-Louis - Lariboisière - F. Widal, Département de Psychiatrie et de Médecine Addictologique, 75475 Paris Cedex 10, France. 4. CHRU de Lille, Pôle de psychiatrie, Hôpital Fontan, Lille 59000, France; Univ Lille, CNRS UMR-9193 (SCA-Lab) & CHU Lille, Hôpital Fontan (CURE), F-59000 Lille, France. 5. EPSM Lille Métropole, Centre Collaborateur de l'Organisation Mondiale de la Santé pour la Recherche et la Formation en Santé Mentale, Equipe Eceve Inserm UMR 1123, Lille, France. 6. CHRU de Lille, Pôle de psychiatrie, Hôpital Fontan, Lille 59000, France; Univ Lyon 1, CRNL, Inserm U1028 / CNRS UMR5292, CH Le Vinatier, Bron, F-69500, France. 7. CHRU de Lille, Pôle de psychiatrie, Hôpital Fontan, Lille 59000, France; Univ Lille, CNRS UMR-9193 (SCA-Lab) & CHU Lille, Hôpital Fontan (CURE), F-59000 Lille, France; Fédération Régionale de Recherche en Santé Mentale (F2RSM) Nord - Pas-de-Calais, F-59000 Lille, France.
Abstract
BACKGROUND: We aimed to explore the sociodemographic and psychiatric correlates of psychotic symptoms in a large general population sample. METHODS: The French Mental Health in the General Population cross-sectional survey interviewed 38,694 individuals using the Mini International Neuropsychiatric Interview. We looked for associations between the presence of lifetime psychotic symptoms, sociodemographic characteristics (including migrant status over three generations) and clinical characteristics. We then looked for associations regarding only hallucinations, delusional symptoms, and the co-occurrence of both hallucinations and delusional symptoms. To test the psychosis continuum hypothesis, associations with sociodemographic characteristics were compared with the characterized psychotic disorders' associations. RESULTS: We found that 22.3% of the population declared psychotic symptoms without psychotic disorders, including 5.7% who declared hallucinations, 20.5% delusional symptoms, 4.0% both hallucinations and delusional symptoms, and 2.8% characterized psychotic disorders. The presence of psychotic symptoms was associated with young age, migrant status (over three generations), secondary education level, low-income level and never-married and separated marital status. Hallucinations, delusional symptoms and the co-occurrence of both hallucinations and delusional symptoms showed the same correlates, and hallucinations were also associated with elementary education level. Characterized psychotic disorders showed the same correlates. Concerning clinical outcomes, the presence of psychotic symptoms, hallucinations and delusional symptoms was associated with all non-psychotic disorders, i.e., bipolar, depressive, alcohol use, generalized anxiety, social phobia, panic and post-traumatic stress disorders and dysthymia (except dysthymia, which was not associated with hallucinations). CONCLUSIONS: Our results indicate that psychotic symptoms are associated with broad psychopathologies and support the continuum model of psychosis.
BACKGROUND: We aimed to explore the sociodemographic and psychiatric correlates of psychotic symptoms in a large general population sample. METHODS: The French Mental Health in the General Population cross-sectional survey interviewed 38,694 individuals using the Mini International Neuropsychiatric Interview. We looked for associations between the presence of lifetime psychotic symptoms, sociodemographic characteristics (including migrant status over three generations) and clinical characteristics. We then looked for associations regarding only hallucinations, delusional symptoms, and the co-occurrence of both hallucinations and delusional symptoms. To test the psychosis continuum hypothesis, associations with sociodemographic characteristics were compared with the characterized psychotic disorders' associations. RESULTS: We found that 22.3% of the population declared psychotic symptoms without psychotic disorders, including 5.7% who declared hallucinations, 20.5% delusional symptoms, 4.0% both hallucinations and delusional symptoms, and 2.8% characterized psychotic disorders. The presence of psychotic symptoms was associated with young age, migrant status (over three generations), secondary education level, low-income level and never-married and separated marital status. Hallucinations, delusional symptoms and the co-occurrence of both hallucinations and delusional symptoms showed the same correlates, and hallucinations were also associated with elementary education level. Characterized psychotic disorders showed the same correlates. Concerning clinical outcomes, the presence of psychotic symptoms, hallucinations and delusional symptoms was associated with all non-psychotic disorders, i.e., bipolar, depressive, alcohol use, generalized anxiety, social phobia, panic and post-traumatic stress disorders and dysthymia (except dysthymia, which was not associated with hallucinations). CONCLUSIONS: Our results indicate that psychotic symptoms are associated with broad psychopathologies and support the continuum model of psychosis.
Authors: Baptiste Pignon; Franck Schürhoff; Grégoire Baudin; Andrea Tortelli; Aziz Ferchiou; Ghassen Saba; Jean-Romain Richard; Antoine Pelissolo; Marion Leboyer; Andrei Szöke Journal: Int J Methods Psychiatr Res Date: 2018-05-22 Impact factor: 4.035
Authors: Baptiste Pignon; Mohamed Lajnef; James B Kirkbride; Hugo Peyre; Aziz Ferchiou; Jean-Romain Richard; Grégoire Baudin; Sarah Tosato; Hannah Jongsma; Lieuwe de Haan; Ilaria Tarricone; Miguel Bernardo; Eva Velthorst; Mauro Braca; Celso Arango; Manuel Arrojo; Julio Bobes; Cristina Marta Del-Ben; Marta Di Forti; Charlotte Gayer-Anderson; Peter B Jones; Caterina La Cascia; Antonio Lasalvia; Paulo Rossi Menezes; Diego Quattrone; Julio Sanjuán; Jean-Paul Selten; Andrea Tortelli; Pierre-Michel Llorca; Jim van Os; Bart P F Rutten; Robin M Murray; Craig Morgan; Marion Leboyer; Andrei Szöke; Franck Schürhoff Journal: Schizophr Bull Date: 2021-10-21 Impact factor: 9.306
Authors: Sara Siddi; Susana Ochoa; Frank Laroi; Matteo Cella; Andrea Raballo; Sandra Saldivia; Yanet Quijada; Julien Laloyaux; Nuno Barbosa Rocha; Tania M Lincoln; Björn Schlier; Evangelos Ntouros; Vasileios P Bozikas; Lukasz Gaweda; Sergio Machado; Antonio E Nardi; Demián Rodante; Smita N Deshpande; Josep Maria Haro; Antonio Preti Journal: Schizophr Bull Date: 2019-02-01 Impact factor: 9.306
Authors: Maria Alice Brito; Ali Amad; Benjamin Rolland; Pierre A Geoffroy; Hugo Peyre; Jean-Luc Roelandt; Imane Benradia; Pierre Thomas; Guillaume Vaiva; Franck Schürhoff; Baptiste Pignon Journal: Eur Arch Psychiatry Clin Neurosci Date: 2021-02-10 Impact factor: 5.270