Literature DB >> 28686069

Heterocyclic thioglycosides in carbohydrate research: Synthesis of thiophene thioglycosides.

Galal H Elgemeie1, Mamdouh A Abu-Zaied2.   

Abstract

A novel synthesis of thiophene thioglycosides is carried out via a one-pot reaction of sodium thiophenethiolates with α-halogeno sugars. The sodium thiophenethiolate salts were prepared using sodium cyanoethylene thiolate salts. The structures of the reaction products were established on the basis of their elemental analysis and spectral data (IR, 1H NMR, MS, and 13C NMR).

Entities:  

Keywords:  Mercaptothiophenes; antimetabolites; glycosides; ketene dithioacetals; sodium thiophenethiolates; thiophene thioglycosides

Mesh:

Substances:

Year:  2017        PMID: 28686069     DOI: 10.1080/15257770.2017.1332371

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN: 1525-7770            Impact factor:   1.381


  4 in total

1.  Synthesis, characterization, and antimicrobial evaluation of novel 5-benzoyl-N-substituted amino- and 5-benzoyl-N-sulfonylamino-4-alkylsulfanyl-2-pyridones.

Authors:  Galal Elgemeie; Farag Altalbawy; Mohammed Alfaidi; Rania Azab; Atef Hassan
Journal:  Drug Des Devel Ther       Date:  2017-11-28       Impact factor: 4.162

2.  Novel purine thioglycoside analogs: synthesis, nanoformulation and biological evaluation in in vitro human liver and breast cancer models.

Authors:  Mamdouh A Abu-Zaied; Samah A Loutfy; Ashraf E Hassan; Galal H Elgemeie
Journal:  Drug Des Devel Ther       Date:  2019-07-26       Impact factor: 4.319

3.  Crystal structure of racemic 2-[(β-arabino-pyran-osyl)-sulfanyl]-4,6-diphenylpyridine-3-carbo-nitrile.

Authors:  Sherif F Hammad; Doaa M Masoud; Galal H Elgemeie; Peter G Jones
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2018-05-25

4.  Design, synthesis, docking, and antimicrobial evaluation of some novel pyrazolo[1,5-a] pyrimidines and their corresponding cycloalkane ring-fused derivatives as purine analogs.

Authors:  Amira E M Abdallah; Galal H Elgemeie
Journal:  Drug Des Devel Ther       Date:  2018-06-20       Impact factor: 4.162

  4 in total

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