Literature DB >> 28674746

The relationship between protein quantity, BMD and fractures in older adults.

J M G Curneen1, M Casey2, E Laird3.   

Abstract

BACKGROUND: Previously, no large-scale literature reviews have focussed on the relationship between dietary protein and its impact on bone mineral density (BMD) and fracture risk-as measures of bone health-in older adults and its potential impact as a primary prevention tool. AIMS: The aim of this study was to assess the impact of varying dietary protein levels on bone health.
METHODS: A literature review of trials concerning older adults' (>50 years of age) and animals' varying protein intake in the diet and its effect on BMD (human and animal) and fracture risk (human only) was carried out. Additionally, a review of dietary assessment tools used in these studies was also analysed.
RESULTS: Ten out of fourteen trials assessing BMD and dietary protein quantity in humans and 3/4 in animal trials found a positive relationship between these two parameters. Four out of seven trials investigating the relationship between dietary protein quantity and fracture risk displayed a positive, protective effect of dietary protein levels on fracture risk. Sixty-two percent of studies used the Food-Frequency Questionnaire assessment method. DISCUSSION: Increased protein intake in the diet is beneficial to bone health and reduces morbidity and mortality. The importance of using dietary protein, along with calcium and vitamin D, as a primary preventative strategy should be stressed, given the health and cost benefits that this would deliver, with a possible need for a higher level of protein in the diet of an elderly person than what is currently recommended.

Entities:  

Keywords:  BMD; Elderly; Fracture; Nutrition; Protein

Mesh:

Substances:

Year:  2017        PMID: 28674746     DOI: 10.1007/s11845-017-1642-8

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  84 in total

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Authors:  S Bourrin; A Toromanoff; P Ammann; J P Bonjour; R Rizzoli
Journal:  J Bone Miner Res       Date:  2000-08       Impact factor: 6.741

Review 3.  Osteoporosis and its management.

Authors:  Kenneth E S Poole; Juliet E Compston
Journal:  BMJ       Date:  2006-12-16

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Authors:  Janet R Hunt; Luann K Johnson; Z K Fariba Roughead
Journal:  Am J Clin Nutr       Date:  2009-03-11       Impact factor: 7.045

5.  Mortality after all major types of osteoporotic fracture in men and women: an observational study.

Authors:  J R Center; T V Nguyen; D Schneider; P N Sambrook; J A Eisman
Journal:  Lancet       Date:  1999-03-13       Impact factor: 79.321

6.  Human bone collagen synthesis is a rapid, nutritionally modulated process.

Authors:  John A Babraj; Kenneth Smith; Daniel J R Cuthbertson; Peter Rickhuss; James S Dorling; Michael J Rennie
Journal:  J Bone Miner Res       Date:  2005-02-14       Impact factor: 6.741

7.  Economic consequences of falls and fractures among older people.

Authors:  B Gannon; E O'Shea; E Hudson
Journal:  Ir Med J       Date:  2008-06

8.  Benefits of oral protein supplementation in elderly patients with fracture of the proximal femur.

Authors:  L Tkatch; C H Rapin; R Rizzoli; D Slosman; V Nydegger; H Vasey; J P Bonjour
Journal:  J Am Coll Nutr       Date:  1992-10       Impact factor: 3.169

Review 9.  Amount and type of protein influences bone health.

Authors:  Robert P Heaney; Donald K Layman
Journal:  Am J Clin Nutr       Date:  2008-05       Impact factor: 7.045

10.  Protective effect of high protein and calcium intake on the risk of hip fracture in the Framingham offspring cohort.

Authors:  Shivani Sahni; L Adrienne Cupples; Robert R McLean; Katherine L Tucker; Kerry E Broe; Douglas P Kiel; Marian T Hannan
Journal:  J Bone Miner Res       Date:  2010-07-26       Impact factor: 6.741

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