Literature DB >> 18469289

Amount and type of protein influences bone health.

Robert P Heaney1, Donald K Layman.   

Abstract

Many factors influence bone mass. Protein has been identified as being both detrimental and beneficial to bone health, depending on a variety of factors, including the level of protein in the diet, the protein source, calcium intake, weight loss, and the acid/base balance of the diet. This review aims to briefly describe these factors and their relation to bone health. Loss of bone mass (osteopenia) and loss of muscle mass (sarcopenia) that occur with age are closely related. Factors that affect muscle anabolism, including protein intake, also affect bone mass. Changes in bone mass, muscle mass, and strength track together over the life span. Bone health is a multifactorial musculoskeletal issue. Calcium and protein intake interact constructively to affect bone health. Intakes of both calcium and protein must be adequate to fully realize the benefit of each nutrient on bone. Optimal protein intake for bone health is likely higher than current recommended intakes, particularly in the elderly. Concerns about dietary protein increasing urinary calcium appear to be offset by increases in absorption. Likewise, concerns about the impact of protein on acid production appear to be minor compared with the alkalinizing effects of fruits and vegetables. Perhaps more concern should be focused on increasing fruit and vegetable intake rather than reducing protein sources. The issue for public health professionals is whether recommended protein intakes should be increased, given the prevalence of osteoporosis and sarcopenia.

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Year:  2008        PMID: 18469289     DOI: 10.1093/ajcn/87.5.1567S

Source DB:  PubMed          Journal:  Am J Clin Nutr        ISSN: 0002-9165            Impact factor:   7.045


  58 in total

Review 1.  The interaction between dietary protein and bone health.

Authors:  David Jesudason; Peter Clifton
Journal:  J Bone Miner Metab       Date:  2010-10-26       Impact factor: 2.626

2.  Effect of a hypocaloric, nutritionally complete, higher-protein meal plan on bone density and quality in older adults with obesity: a randomized trial.

Authors:  Ashley A Weaver; Denise K Houston; Sue A Shapses; Mary F Lyles; Rebecca M Henderson; Daniel P Beavers; Arlynn C Baker; Kristen M Beavers
Journal:  Am J Clin Nutr       Date:  2019-02-01       Impact factor: 7.045

Review 3.  A look behind the scenes: the risk and pathogenesis of primary osteoporosis.

Authors:  Gretl Hendrickx; Eveline Boudin; Wim Van Hul
Journal:  Nat Rev Rheumatol       Date:  2015-04-21       Impact factor: 20.543

4.  Nutrition and Bone Density in Boys with Autism Spectrum Disorder.

Authors:  Ann M Neumeyer; Natalia Cano Sokoloff; Erin I McDonnell; Eric A Macklin; Christopher J McDougle; Tara M Holmes; Jane L Hubbard; Madhusmita Misra
Journal:  J Acad Nutr Diet       Date:  2018-03-02       Impact factor: 4.910

Review 5.  Dietary Approaches for Bone Health: Lessons from the Framingham Osteoporosis Study.

Authors:  Shivani Sahni; Kelsey M Mangano; Robert R McLean; Marian T Hannan; Douglas P Kiel
Journal:  Curr Osteoporos Rep       Date:  2015-08       Impact factor: 5.096

6.  Protein intake and incident frailty in the Women's Health Initiative observational study.

Authors:  Jeannette M Beasley; Andrea Z LaCroix; Marian L Neuhouser; Ying Huang; Lesley Tinker; Nancy Woods; Yvonne Michael; J David Curb; Ross L Prentice
Journal:  J Am Geriatr Soc       Date:  2010-05-07       Impact factor: 5.562

7.  Biomarker-calibrated protein intake and bone health in the Women's Health Initiative clinical trials and observational study.

Authors:  Jeannette M Beasley; Andrea Z LaCroix; Joseph C Larson; Ying Huang; Marian L Neuhouser; Lesley F Tinker; Rebecca Jackson; Linda Snetselaar; Karen C Johnson; Charles B Eaton; Ross L Prentice
Journal:  Am J Clin Nutr       Date:  2014-02-19       Impact factor: 7.045

8.  Increased Consumption of Plant Foods Is Associated with Increased Bone Mineral Density.

Authors:  J Berg; N Seyedsadjadi; R Grant
Journal:  J Nutr Health Aging       Date:  2020       Impact factor: 4.075

9.  Dietary protein in relation to bone stiffness index and fat-free mass in a population consuming relatively low protein diets.

Authors:  Sun Min Oh; Hyeon Chang Kim; Yumie Rhee; Seon-Joo Park; Hae-Jeung Lee; Il Suh; Diane Feskanich
Journal:  J Bone Miner Metab       Date:  2013-02-19       Impact factor: 2.626

10.  Dietary protein safety and resistance exercise: what do we really know?

Authors:  Lonnie M Lowery; Lorena Devia
Journal:  J Int Soc Sports Nutr       Date:  2009-01-12       Impact factor: 5.150

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