Literature DB >> 28634646

The Role of Robotics in the Invasive Management of Bladder Cancer.

Pramit Khetrapal1,2, Wei Shen Tan3,4, Benjamin Lamb3, Melanie Tan3, Hilary Baker3, James Thompson3, Ashwin Sridhar3, John D Kelly3,4, Tim Briggs3.   

Abstract

Robot-assisted radical cystectomy (RARC) has been adopted widely in many centres, owed largely to the success of robot-assisted laparoscopic prostatectomy (RALP). It aims to replicate the oncological outcomes of open radical cystectomy (ORC), while providing a shorter recovery period. Despite this, previous RCTs have failed to show a benefit for RARC over ORC. These trials have compared extracorporeal RARC (eRARC) with ORC, which requires a further incision to mobilise the bowel for urinary reconstruction with an open technique. For intracorporeal RARC (iRARC), this urinary reconstruction is performed robotically without further incisions. There are theoretical benefits to this approach such as reduced recovery time for the bowel and reduced ileus rates, but no level 1 evidence currently exists to support this. While there has been an improvement in patient outcomes since the adoption of RARC, various other factors, such as enhanced recovery programmes and surgical learning curve, have made it difficult to attribute this solely to the robotic approach as many centres performing ORC have also shown similar improvements. In this review, we will discuss implementation of RARC as well as perioperative measures that have helped improve outcomes, offer a comparison of outcomes between ORC and RARC and highlight upcoming RCTs that may offer new evidence for or against a paradigm shift in the future of bladder cancer surgery.

Entities:  

Keywords:  Bladder cancer; Enhanced recovery; Extracorporeal; Intracorporeal; Robotic cystectomy

Mesh:

Year:  2017        PMID: 28634646     DOI: 10.1007/s11934-017-0706-7

Source DB:  PubMed          Journal:  Curr Urol Rep        ISSN: 1527-2737            Impact factor:   3.092


  49 in total

Review 1.  Insulin resistance: a marker of surgical stress.

Authors:  A Thorell; J Nygren; O Ljungqvist
Journal:  Curr Opin Clin Nutr Metab Care       Date:  1999-01       Impact factor: 4.294

Review 2.  Systematic review and cumulative analysis of oncologic and functional outcomes after robot-assisted radical cystectomy.

Authors:  Bertram Yuh; Timothy Wilson; Bernie Bochner; Kevin Chan; Joan Palou; Arnulf Stenzl; Francesco Montorsi; George Thalmann; Khurshid Guru; James W F Catto; Peter N Wiklund; Giacomo Novara
Journal:  Eur Urol       Date:  2015-01-02       Impact factor: 20.096

3.  Analysis of open and intracorporeal robotic assisted radical cystectomy shows no significant difference in recurrence patterns and oncological outcomes.

Authors:  Wei Shen Tan; Ashwin Sridhar; Gidon Ellis; Benjamin Lamb; Miles Goldstraw; Senthil Nathan; John Hines; Paul Cathcart; Tim Briggs; John Kelly
Journal:  Urol Oncol       Date:  2016-03-08       Impact factor: 3.498

4.  Health-related quality of life from a prospective randomised clinical trial of robot-assisted laparoscopic vs open radical cystectomy.

Authors:  Jamie C Messer; Sanoj Punnen; John Fitzgerald; Robert Svatek; Dipen J Parekh
Journal:  BJU Int       Date:  2014-08-13       Impact factor: 5.588

5.  Early oncological outcomes for bladder urothelial carcinoma patients treated with robotic-assisted radical cystectomy.

Authors:  Eric C Kauffman; Casey K Ng; Ming Ming Lee; Brandon J Otto; Gerald J Wang; Douglas S Scherr
Journal:  BJU Int       Date:  2010-09-30       Impact factor: 5.588

6.  Benefits of robotic cystectomy with intracorporeal diversion for patients with low cardiorespiratory fitness: A prospective cohort study.

Authors:  Benjamin Wilfrid Lamb; Wei Shen Tan; Philip Eneje; David Bruce; Amy Jones; Imran Ahmad; Ashwin Sridhar; Hilary Baker; Tim P Briggs; John E Hines; Senthil Nathan; Daniel Martin; Robert C Stephens; John D Kelly
Journal:  Urol Oncol       Date:  2016-05-16       Impact factor: 3.498

7.  Evolution of the Southampton Enhanced Recovery Programme for radical cystectomy and the aggregation of marginal gains.

Authors:  Julian Smith; Zhao Wu Meng; Richard Lockyer; Tim Dudderidge; John McGrath; Matthew Hayes; Brian Birch
Journal:  BJU Int       Date:  2014-07-27       Impact factor: 5.588

8.  Robotic-assisted laparoscopic intracorporeal urinary diversion.

Authors:  Raj S Pruthi; Jeff Nix; Dan McRackan; Adam Hickerson; Matthew E Nielsen; Matthew Raynor; Eric M Wallen
Journal:  Eur Urol       Date:  2010-01-09       Impact factor: 20.096

Review 9.  Complications of Radical Cystectomy and Orthotopic Reconstruction.

Authors:  Wei Shen Tan; Benjamin W Lamb; John D Kelly
Journal:  Adv Urol       Date:  2015-11-30

10.  Analysis of intracorporeal compared with extracorporeal urinary diversion after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium.

Authors:  Kamran Ahmed; Shahid A Khan; Matthew H Hayn; Piyush K Agarwal; Ketan K Badani; M Derya Balbay; Erik P Castle; Prokar Dasgupta; Reza Ghavamian; Khurshid A Guru; Ashok K Hemal; Brent K Hollenbeck; Adam S Kibel; Mani Menon; Alex Mottrie; Kenneth Nepple; John G Pattaras; James O Peabody; Vassilis Poulakis; Raj S Pruthi; Joan Palou Redorta; Koon-Ho Rha; Lee Richstone; Matthias Saar; Douglas S Scherr; Stefan Siemer; Michael Stoeckle; Eric M Wallen; Alon Z Weizer; Peter Wiklund; Timothy Wilson; Michael Woods; Muhammad Shamim Khan
Journal:  Eur Urol       Date:  2013-10-09       Impact factor: 20.096

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