Literature DB >> 286328

Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies.

M Herlyn, Z Steplewski, D Herlyn, H Koprowski.   

Abstract

Fusion of P3 X 63 Ag8 mouse myeloma cells with splenocytes obtained from mice immunized with cells derived from human colorectal carcinomas resulted in the production of antibody-secreting hybridomas. Two hybridomas (1083-17 and 1116-56) and their clones secreted antibodies binding specifically to human colorectal carcinoma cells either grown in culture or obtained from patients, but did not bind to normal colonic mucosa or other normal and malignant human cells. The binding specificity was consistent in three assays: radioimmunoassay, mixed hemadsorption, and immunofluorescence. Adsorption of these antibodies to colorectal carcinoma cell lines totally eliminated their specific binding.

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Year:  1979        PMID： 286328      PMCID： PMC383267          DOI： 10.1073/pnas.76.3.1438

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  13 in total

1.  Detection of antigens in tissue culture with the aid of mixed hemadsorption.

Authors:  A ESPMARK; A FAGRAEUS
Journal:  Acta Pathol Microbiol Scand Suppl       Date:  1962

2.  Cloning of immunoglobulin-producing human leukemic and lymphoma cells in long-term cultures.

Authors:  Y Hinuma; J T Grace
Journal:  Proc Soc Exp Biol Med       Date:  1967-01

Review 3.  Oncofetal and other tumor-associated antigens of the human digestive system.

Authors:  D M Goldenberg
Journal:  Curr Top Pathol       Date:  1976

4.  Lymphocyte cytotoxicity against autologous tumour biopsy cells in humans.

Authors:  B M Vose; F Vanky; E Klein
Journal:  Int J Cancer       Date:  1977-10-15       Impact factor: 7.396

5.  Classification of human colorectal adenocarcinoma cell lines.

Authors:  A Leibovitz; J C Stinson; W B McCombs; C E McCoy; K C Mazur; N D Mabry
Journal:  Cancer Res       Date:  1976-12       Impact factor: 12.701

6.  Immunology and immunotherapy of colorectal cancer.

Authors:  P Gold
Journal:  Can J Surg       Date:  1978-05       Impact factor: 2.089

7.  Lymphoblastoid cell lines from patients with chronic lymphocytic leukemia: identification of tumor origin by idiotypic analysis.

Authors:  J N Hurley; S M Fu; H G Kunkel; G McKenna; M D Scharff
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

8.  Study of antibodies against human melanoma produced by somatic cell hybrids.

Authors:  H Koprowski; Z Steplewski; D Herlyn; M Herlyn
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

9.  Cell surface antigens of human malignant melanoma: mixed hemadsorption assays for humoral immunity to cultured autologous melanoma cells.

Authors:  T E Carey; T Takahashi; L A Resnick; H F Oettgen; L J Old
Journal:  Proc Natl Acad Sci U S A       Date:  1976-09       Impact factor: 11.205

10.  Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells.

Authors:  H Koprowski; W Gerhard; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205
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  160 in total

1.  Epidermal growth factor-like repeats mediate lateral and reciprocal interactions of Ep-CAM molecules in homophilic adhesions.

Authors:  M Balzar; I H Briaire-de Bruijn; H A Rees-Bakker; F A Prins; W Helfrich; L de Leij; G Riethmüller; S Alberti; S O Warnaar; G J Fleuren; S V Litvinov
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272

Review 2.  EpCAM and its potential role in tumor-initiating cells.

Authors:  Sannia Imrich; Matthias Hachmeister; Olivier Gires
Journal:  Cell Adh Migr       Date:  2012 Jan-Feb       Impact factor: 3.405

Review 3.  The detection and discovery of glycan motifs in biological samples using lectins and antibodies: new methods and opportunities.

Authors:  Huiyuan Tang; Peter Hsueh; Doron Kletter; Marshall Bern; Brian Haab
Journal:  Adv Cancer Res       Date:  2015-02-07       Impact factor: 6.242

4.  Normal colon of Sprague-Dawley rats. An immunohistochemical study.

Authors:  J D Shetye; C A Rubio; H T Mellstedt
Journal:  Anat Embryol (Berl)       Date:  1992

Review 5.  A comprehensive overview of radioguided surgery using gamma detection probe technology.

Authors:  Stephen P Povoski; Ryan L Neff; Cathy M Mojzisik; David M O'Malley; George H Hinkle; Nathan C Hall; Douglas A Murrey; Michael V Knopp; Edward W Martin
Journal:  World J Surg Oncol       Date:  2009-01-27       Impact factor: 2.754

6.  Ablation of human colon carcinoma in nude mice by 131I-labeled monoclonal anti-carcinoembryonic antigen antibody F(ab')2 fragments.

Authors:  F Buchegger; C Pfister; K Fournier; F Prevel; M Schreyer; S Carrel; J P Mach
Journal:  J Clin Invest       Date:  1989-05       Impact factor: 14.808

7.  Studies of mammalian ornithine decarboxylase using a monoclonal antibody.

Authors:  A E Pegg; J E Seely; L Persson; M Herlyn; K Ponsell; T G O'Brien
Journal:  Biochem J       Date:  1984-01-01       Impact factor: 3.857

8.  Monoclonal antibodies reactive with human myeloid leukaemia cells.

Authors:  E D Ball; M W Fanger
Journal:  Clin Exp Immunol       Date:  1982-06       Impact factor: 4.330

9.  Selecting binding and complement-mediated lysis of human hepatoma cells (PLC/PRF/5) in culture by monoclonal antibodies to hepatitis B surface antigen.

Authors:  D Shouval; J R Wands; V R Zurawski; K J Isselbacher; D A Shafritz
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

10.  Monoclonal antibody against ependymoma-derived cell line.

Authors:  Y Mihara; Y Matsukado; S Goto; Y Ushio; S Tokumitsu; K Takahashi
Journal:  J Neurooncol       Date:  1992-01       Impact factor: 4.130
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