Literature DB >> 286321

DNA fragments of the Mus musculus beta globin haplotypes Hbbs and Hbbd.

S Weaver, N L Haigwood, C A Hutchison, M H Edgell.   

Abstract

Two alternative haplotypes at the complex locus controlling hemoglobin beta chain synthesis in Mus musculus were compared at the DNA level. As expected, Hbbd homozygotes--which as adults synthesize two species of beta chain--have two genes for beta globin. Adult mice homozygous for the Hbbs haplotype make only a single type of beta polypeptide, yet they also have two beta globin genes. Apparently the two Hbbs genes encode identical proteins, or one of the two genes is not detectably expressed. The Hbbs and Hbbd haplotypes are thus more similar at the DNA level than studies of their polypeptide products have indicated.

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Year:  1979        PMID: 286321      PMCID: PMC383256          DOI: 10.1073/pnas.76.3.1385

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  20 in total

1.  Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.

Authors:  S M Tilghman; D C Tiemeier; F Polsky; M H Edgell; J G Seidman; A Leder; L W Enquist; B Norman; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

2.  Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.

Authors:  S M Tilghman; D C Tiemeier; J G Seidman; B M Peterlin; M Sullivan; J V Maizel; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1978-02       Impact factor: 11.205

3.  The cloning of mouse globin and surrounding gene sequences in bacteriophage lambda.

Authors:  P Leder; S M Tilghman; D C Tiemeier; F I Polsky; J G Seidman; M H Edgell; L W Enquist; A Leder; B Norman
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1978

4.  A comparison of two cloned mouse beta-globin genes and their surrounding and intervening sequences.

Authors:  D C Tiemeier; S M Tilghman; F I Polsky; J G Seidman; A Leder; M H Edgell; P Leder
Journal:  Cell       Date:  1978-06       Impact factor: 41.582

5.  High capacity gel preparative electrophoresis for purification of fragments of genomic DNA.

Authors:  F Polsky; M H Edgell; J G Seidman; P Leder
Journal:  Anal Biochem       Date:  1978-07-01       Impact factor: 3.365

6.  X-ray intensifying screens greatly enhance the detection by autoradiography of the radioactive isotopes 32P and 125I.

Authors:  R Swanstrom; P R Shank
Journal:  Anal Biochem       Date:  1978-05       Impact factor: 3.365

7.  The rabbit beta-globin gene contains a large large insert in the coding sequence.

Authors:  A J Jeffreys; R A Flavell
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

8.  Differential control of the synthesis of two hemoglobin beta chains in normal mice.

Authors:  J B Whitney
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

9.  Cloning and amplification of alpha and beta mouse globin gene sequences synthesised in vitro.

Authors:  F Rougeon; B Mach
Journal:  Gene       Date:  1977-05       Impact factor: 3.688

10.  Changes in restricted human cellular DNA fragments containing globin gene sequences in thalassemias and related disorders.

Authors:  J G Mears; F Ramirez; D Leibowitz; F Nakamura; A Bloom; F Konotey-Ahulu; A Bank
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

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  9 in total

1.  Retrovirus-mediated transfer and expression of the interleukin-3 gene in mouse hematopoietic cells result in a myeloproliferative disorder.

Authors:  P M Wong; S W Chung; C E Dunbar; D M Bodine; S Ruscetti; A W Nienhuis
Journal:  Mol Cell Biol       Date:  1989-02       Impact factor: 4.272

2.  beta-globin transcript found in induced murine erythroleukemia cells is homologous to the beta h0 and beta h1 genes.

Authors:  B A Brown; R W Padgett; S C Hardies; C A Hutchison; M H Edgell
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

3.  Analysis of a mouse alpha-globin gene mutation induced by ethylnitrosourea.

Authors:  R A Popp; E G Bailiff; L C Skow; F M Johnson; S E Lewis
Journal:  Genetics       Date:  1983-09       Impact factor: 4.562

4.  Evolutionary conservation of linkage groups: additional evidence from murid and cricetid rodents.

Authors:  L R Snyder
Journal:  Biochem Genet       Date:  1980-04       Impact factor: 1.890

5.  Silent delta-globin gene in Old World monkeys.

Authors:  S L Martin; E A Zimmer; Y W Kan; A C Wilson
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

6.  A mutation in the beta-globin gene detected in the progeny of a female mouse treated with ethylnitrosourea.

Authors:  S E Lewis; F M Johnson; L C Skow; D Popp; L B Barnett; R A Popp
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

7.  Number and location of mouse mammary tumor virus proviral DNA in mouse DNA of normal tissue and of mammary tumors.

Authors:  B Groner; N E Hynes
Journal:  J Virol       Date:  1980-03       Impact factor: 5.103

8.  Three mouse models of human thalassemia.

Authors:  J Martinell; J B Whitney; R A Popp; L B Russell; W F Anderson
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

9.  Replication of alpha and beta globin DNA sequences occurs during early S phase in murine erythroleukemia cells.

Authors:  E Epner; R A Rifkind; P A Marks
Journal:  Proc Natl Acad Sci U S A       Date:  1981-05       Impact factor: 11.205

  9 in total

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