Amy E Wright1, Cameron Davis1, Yessenia Gomez1, Joseph Posner1, Christopher Rorden2, Argye E Hillis3, Donna C Tippett4. 1. Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, MD. 2. Center for Aphasia Research and Rehabilitation, University of South Carolina, Columbia, SC. 3. Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, MD. Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD. Department of Cognitive Science, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD. 4. Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, MD. Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD. Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Abstract
PURPOSE: We aimed to: (a) review existing data on the neural basis of affective prosody;(b) test the hypothesis that there are double dissociations in impairments of expression and recognition of affective prosody; and (c) identify areas of infarct associated with impaired expression and/or recognition of affective prosody after acute right hemisphere (RH) ischemic stroke. METHODS: Participants were tested on recognition of emotional prosody in content-neutral sentences. Expression was evaluated by measuring variability in fundamental frequency. Voxel-based symptom mapping was used to identify areas associated with severity of expressive deficits. RESULTS: We found that 9/23 patients had expressive prosody impairments; 5/9 of these patients also had impaired recognition of affective prosody; 2/9 had selective deficits in expressive prosody; recognition was not tested in 2/9. Another 6/23 patients had selective impairment in recognition of affective prosody. Severity of expressive deficits was associated with lesions in right temporal pole; patients with temporal pole lesions had deficits in expression and recognition. CONCLUSIONS: Expression and recognition of prosody can be selectively impaired. Damage to right anterior temporal pole is associated with impairment of both, indicating a role of this structure in a mechanism shared by expression and production of affective prosody.
PURPOSE: We aimed to: (a) review existing data on the neural basis of affective prosody;(b) test the hypothesis that there are double dissociations in impairments of expression and recognition of affective prosody; and (c) identify areas of infarct associated with impaired expression and/or recognition of affective prosody after acute right hemisphere (RH) ischemic stroke. METHODS:Participants were tested on recognition of emotional prosody in content-neutral sentences. Expression was evaluated by measuring variability in fundamental frequency. Voxel-based symptom mapping was used to identify areas associated with severity of expressive deficits. RESULTS: We found that 9/23 patients had expressive prosody impairments; 5/9 of these patients also had impaired recognition of affective prosody; 2/9 had selective deficits in expressive prosody; recognition was not tested in 2/9. Another 6/23 patients had selective impairment in recognition of affective prosody. Severity of expressive deficits was associated with lesions in right temporal pole; patients with temporal pole lesions had deficits in expression and recognition. CONCLUSIONS: Expression and recognition of prosody can be selectively impaired. Damage to right anterior temporal pole is associated with impairment of both, indicating a role of this structure in a mechanism shared by expression and production of affective prosody.
Authors: E D Ross; D M Orbelo; J Cartwright; S Hansel; M Burgard; J A Testa; R Buck Journal: J Neurol Neurosurg Psychiatry Date: 2001-05 Impact factor: 10.154
Authors: Julius Fridriksson; Dana Moser; Jack Ryalls; Leonardo Bonilha; Chris Rorden; Gordon Baylis Journal: J Speech Lang Hear Res Date: 2008-10-31 Impact factor: 2.297
Authors: James R Bateman; Christopher M Filley; Elliott D Ross; Brianne M Bettcher; H Isabel Hubbard; Miranda Babiak; Peter S Pressman Journal: Neurocase Date: 2019-07-23 Impact factor: 0.881
Authors: Shannon M Sheppard; Erin L Meier; Alexandra Zezinka Durfee; Alex Walker; Jennifer Shea; Argye E Hillis Journal: Cortex Date: 2021-04-24 Impact factor: 4.644
Authors: Sona Patel; Kenichi Oishi; Amy Wright; Harry Sutherland-Foggio; Sadhvi Saxena; Shannon M Sheppard; Argye E Hillis Journal: Front Neurol Date: 2018-04-06 Impact factor: 4.003
Authors: Shannon M Sheppard; Lynsey M Keator; Bonnie L Breining; Amy E Wright; Sadhvi Saxena; Donna C Tippett; Argye E Hillis Journal: Neurology Date: 2019-12-31 Impact factor: 9.910